4-phenylbutyric acid has been researched along with Calcinosis in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Calcinosis: Pathologic deposition of calcium salts in tissues.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, Z | 1 |
| Li, F | 1 |
| Gong, W | 1 |
| Liu, W | 1 |
| Duan, Q | 1 |
| Chen, C | 1 |
| Ni, L | 1 |
| Xia, Y | 1 |
| Cianflone, K | 1 |
| Dong, N | 1 |
| Wang, DW | 1 |
| Pomozi, V | 1 |
| Brampton, C | 1 |
| Szeri, F | 1 |
| Dedinszki, D | 1 |
| Kozák, E | 1 |
| van de Wetering, K | 1 |
| Hopkins, H | 1 |
| Martin, L | 1 |
| Váradi, A | 1 |
| Le Saux, O | 1 |
2 other studies available for 4-phenylbutyric acid and Calcinosis
| Article | Year |
|---|---|
Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals.
Topics: Aged; Animals; Aortic Valve; Aortic Valve Stenosis; Apolipoproteins E; Calcinosis; Calcium; Cell Dif | 2013 |
Functional Rescue of ABCC6 Deficiency by 4-Phenylbutyrate Therapy Reduces Dystrophic Calcification in Abcc6
Topics: Alleles; Animals; ATP-Binding Cassette Transporters; Calcinosis; Cell Membrane; Female; HEK293 Cells | 2017 |