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4-phenylbutyric acid and Blindness

4-phenylbutyric acid has been researched along with Blindness in 1 studies

4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

Blindness: The inability to see or the loss or absence of perception of visual stimuli. This condition may be the result of EYE DISEASES; OPTIC NERVE DISEASES; OPTIC CHIASM diseases; or BRAIN DISEASES affecting the VISUAL PATHWAYS or OCCIPITAL LOBE.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Li, S1
Samardzija, M1
Yang, Z1
Grimm, C1
Jin, M1

Other Studies

1 other study available for 4-phenylbutyric acid and Blindness

ArticleYear
Pharmacological Amelioration of Cone Survival and Vision in a Mouse Model for Leber Congenital Amaurosis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 05-25, Volume: 36, Issue:21

    Topics: Animals; Blindness; Cell Survival; cis-trans-Isomerases; Dose-Response Relationship, Drug; Female; L

2016