4-phenylbutyric acid has been researched along with BCKD Deficiency in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zubarioglu, T | 1 |
| Dede, E | 1 |
| Cigdem, H | 1 |
| Kiykim, E | 1 |
| Cansever, MS | 1 |
| Aktuglu-Zeybek, C | 1 |
1 trial available for 4-phenylbutyric acid and BCKD Deficiency
| Article | Year |
|---|---|
Impact of sodium phenylbutyrate treatment in acute management of maple syrup urine disease attacks: a single-center experience.
Topics: Antineoplastic Agents; Child; Child, Preschool; Disease Management; Female; Follow-Up Studies; Human | 2021 |