4-phenylbutyric acid has been researched along with Autoimmune Diseases in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Autoimmune Diseases: Disorders that are characterized by the production of antibodies that react with host tissues or immune effector cells that are autoreactive to endogenous peptides.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, M | 1 |
| Zhang, Q | 1 |
| Joe, Y | 1 |
| Lee, BH | 1 |
| Ryu, DG | 1 |
| Kwon, KB | 1 |
| Ryter, SW | 1 |
| Chung, HT | 1 |
1 other study available for 4-phenylbutyric acid and Autoimmune Diseases
| Article | Year |
|---|---|
Curcumin induces apoptotic cell death of activated human CD4+ T cells via increasing endoplasmic reticulum stress and mitochondrial dysfunction.
Topics: Apoptosis; Autoimmune Diseases; CD4-Positive T-Lymphocytes; Curcumin; DNA-Binding Proteins; eIF-2 Ki | 2013 |