4-phenylbutyric acid has been researched along with Atrial Fibrillation in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Atrial Fibrillation: Abnormal cardiac rhythm that is characterized by rapid, uncoordinated firing of electrical impulses in the upper chambers of the heart (HEART ATRIA). In such case, blood cannot be effectively pumped into the lower chambers of the heart (HEART VENTRICLES). It is caused by abnormal impulse generation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wiersma, M | 1 |
| Meijering, RAM | 1 |
| Qi, XY | 1 |
| Zhang, D | 1 |
| Liu, T | 1 |
| Hoogstra-Berends, F | 1 |
| Sibon, OCM | 1 |
| Henning, RH | 1 |
| Nattel, S | 1 |
| Brundel, BJJM | 1 |
1 other study available for 4-phenylbutyric acid and Atrial Fibrillation
| Article | Year |
|---|---|
Endoplasmic Reticulum Stress Is Associated With Autophagy and Cardiomyocyte Remodeling in Experimental and Human Atrial Fibrillation.
Topics: Animals; Atrial Fibrillation; Atrial Remodeling; Autophagy; Calcium Channels, L-Type; Calcium Signal | 2017 |