Page last updated: 2024-11-02

4-phenylbutyric acid and Atheroma

4-phenylbutyric acid has been researched along with Atheroma in 3 studies

4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Di, M1
Wang, L1
Li, M1
Zhang, Y2
Liu, X1
Zeng, R1
Wang, H1
Chen, Y1
Chen, W1
Zhang, M1
Espada, S1
Stavik, B1
Holm, S1
Sagen, EL1
Bjerkeli, V1
Skjelland, M1
Dahl, TB1
Espevik, T1
Kanse, S1
Sandset, PM1
Skretting, G1
Halvorsen, B1
Ying, R1
Li, SW1
Chen, JY1
Zhang, HF1
Yang, Y1
Gu, ZJ1
Chen, YX1
Wang, JF1

Other Studies

3 other studies available for 4-phenylbutyric acid and Atheroma

ArticleYear
Dickkopf1 destabilizes atherosclerotic plaques and promotes plaque formation by inducing apoptosis of endothelial cells through activation of ER stress.
    Cell death & disease, 2017, 07-13, Volume: 8, Issue:7

    Topics: Animals; Aorta; Apolipoproteins E; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cytokines; Endo

2017
Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages.
    Biochemical and biophysical research communications, 2017, 09-16, Volume: 491, Issue:2

    Topics: Atherosclerosis; Carotid Arteries; Cholesterol; Crystallization; Endarterectomy, Carotid; Endoplasmi

2017
Endoplasmic reticulum stress in perivascular adipose tissue promotes destabilization of atherosclerotic plaque by regulating GM-CSF paracrine.
    Journal of translational medicine, 2018, 04-18, Volume: 16, Issue:1

    Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Aorta; Cell Movement; Culture Media, Conditioned;

2018