4-phenylbutyric acid has been researched along with Asymmetric Diabetic Proximal Motor Neuropathy in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Inceoglu, B | 1 |
| Bettaieb, A | 1 |
| Trindade da Silva, CA | 1 |
| Lee, KS | 1 |
| Haj, FG | 1 |
| Hammock, BD | 1 |
| Lupachyk, S | 1 |
| Watcho, P | 1 |
| Stavniichuk, R | 1 |
| Shevalye, H | 1 |
| Obrosova, IG | 1 |
2 other studies available for 4-phenylbutyric acid and Asymmetric Diabetic Proximal Motor Neuropathy
| Article | Year |
|---|---|
Endoplasmic reticulum stress in the peripheral nervous system is a significant driver of neuropathic pain.
Topics: Animals; Apoptosis; Autophagy; Blood Glucose; Blotting, Western; Diabetes Mellitus, Experimental; Di | 2015 |
Endoplasmic reticulum stress plays a key role in the pathogenesis of diabetic peripheral neuropathy.
Topics: Animals; CCAAT-Enhancer-Binding Proteins; Diabetic Neuropathies; Endoplasmic Reticulum Stress; Epide | 2013 |