4-phenylbutyric acid has been researched along with Asthma in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Asthma: A form of bronchial disorder with three distinct components: airway hyper-responsiveness (RESPIRATORY HYPERSENSITIVITY), airway INFLAMMATION, and intermittent AIRWAY OBSTRUCTION. It is characterized by spasmodic contraction of airway smooth muscle, WHEEZING, and dyspnea (DYSPNEA, PAROXYSMAL).
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Delmotte, P | 1 |
| Yap, JQ | 1 |
| Dasgupta, D | 1 |
| Sieck, GC | 1 |
| Makhija, L | 1 |
| Krishnan, V | 1 |
| Rehman, R | 1 |
| Chakraborty, S | 1 |
| Maity, S | 1 |
| Mabalirajan, U | 1 |
| Chakraborty, K | 1 |
| Ghosh, B | 1 |
| Agrawal, A | 1 |
2 other studies available for 4-phenylbutyric acid and Asthma
| Article | Year |
|---|---|
Chemical Chaperone 4-PBA Mitigates Tumor Necrosis Factor Alpha-Induced Endoplasmic Reticulum Stress in Human Airway Smooth Muscle.
Topics: Asthma; Endoplasmic Reticulum Stress; Endoribonucleases; Humans; Molecular Chaperones; Muscle, Smoot | 2023 |
Chemical chaperones mitigate experimental asthma by attenuating endoplasmic reticulum stress.
Topics: Airway Remodeling; Animals; Asthma; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Glycerol; I | 2014 |