4-phenylbutyric acid has been researched along with Arthritis, Degenerative in 4 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 1 |
| Zhu, H | 1 |
| Yan, X | 1 |
| Gu, H | 1 |
| Gu, Z | 1 |
| Liu, F | 2 |
| Tang, YH | 1 |
| Yue, ZS | 1 |
| Zheng, WJ | 1 |
| Shen, HF | 1 |
| Zeng, LR | 1 |
| Hu, ZQ | 1 |
| Xiong, ZF | 1 |
| Mallik, A | 1 |
| Yammani, RR | 1 |
| Weng, X | 1 |
| Lin, P | 1 |
| Zheng, C | 1 |
| Xu, H | 1 |
| Liu, X | 1 |
| Ye, H | 1 |
| Li, X | 1 |
4 other studies available for 4-phenylbutyric acid and Arthritis, Degenerative
| Article | Year |
|---|---|
Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritis chondrocytes.
Topics: ADAMTS5 Protein; Apoptosis; beta-Galactosidase; Cartilage, Articular; Cell Survival; Cellular Senesc | 2017 |
4-Phenylbutyric acid presents therapeutic effect on osteoarthritis via inhibiting cell apoptosis and inflammatory response induced by endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Endoplasmic Reticulum Stress; Inflammation; Male; Osteoarthritis; Phenylbutyrate | 2018 |
Saturated fatty acid palmitate negatively regulates autophagy by promoting ATG5 protein degradation in meniscus cells.
Topics: Animals; Autophagy; Autophagy-Related Protein 5; Cells, Cultured; Down-Regulation; Endoplasmic Retic | 2018 |
Duhuo Jisheng decoction inhibits endoplasmic reticulum stress in chondrocytes induced by tunicamycin through the downregulation of miR-34a.
Topics: Animals; Apoptosis; Chondrocytes; Down-Regulation; Drugs, Chinese Herbal; Endoplasmic Reticulum Stre | 2015 |