4-phenylbutyric acid has been researched along with Arteriosclerosis in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Arteriosclerosis: Thickening and loss of elasticity of the walls of ARTERIES of all sizes. There are many forms classified by the types of lesions and arteries involved, such as ATHEROSCLEROSIS with fatty lesions in the ARTERIAL INTIMA of medium and large muscular arteries.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KRITCHEVSKY, D | 1 |
| MOYER, AW | 1 |
| TESAR, WC | 1 |
| MCCANDLESS, RF | 1 |
| LOGAN, JB | 1 |
| BROWN, RA | 1 |
| ENGLERT, M | 1 |
| ZENI, G | 1 |
2 other studies available for 4-phenylbutyric acid and Arteriosclerosis
| Article | Year |
|---|---|
The effect of sodium 2-phenylbutyrate in experimental atherosclerosis.
Topics: Arteriosclerosis; Atherosclerosis; Butyrates; Phenylbutyrates; Sodium | 1956 |
[Sodium phenylbutyrate in the treatment of arteriosclerotic disease].
Topics: Arteriosclerosis; Humans; Phenylacetates; Phenylbutyrates; Sodium | 1958 |