4-phenylbutyric acid has been researched along with Aortic Valve Stenosis in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Aortic Valve Stenosis: A pathological constriction that can occur above (supravalvular stenosis), below (subvalvular stenosis), or at the AORTIC VALVE. It is characterized by restricted outflow from the LEFT VENTRICLE into the AORTA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cai, Z | 1 |
| Li, F | 1 |
| Gong, W | 1 |
| Liu, W | 1 |
| Duan, Q | 1 |
| Chen, C | 1 |
| Ni, L | 1 |
| Xia, Y | 1 |
| Cianflone, K | 1 |
| Dong, N | 1 |
| Wang, DW | 1 |
1 other study available for 4-phenylbutyric acid and Aortic Valve Stenosis
| Article | Year |
|---|---|
Endoplasmic reticulum stress participates in aortic valve calcification in hypercholesterolemic animals.
Topics: Aged; Animals; Aortic Valve; Aortic Valve Stenosis; Apolipoproteins E; Calcinosis; Calcium; Cell Dif | 2013 |