Page last updated: 2024-11-02

4-phenylbutyric acid and Aortic Diseases

4-phenylbutyric acid has been researched along with Aortic Diseases in 1 studies

4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.

Aortic Diseases: Pathological processes involving any part of the AORTA.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Zhu, Q1
Guo, R1
Liu, C1
Fu, D1
Liu, F1
Hu, J1
Jiang, H1

Other Studies

1 other study available for 4-phenylbutyric acid and Aortic Diseases

ArticleYear
Endoplasmic Reticulum Stress-Mediated Apoptosis Contributing to High Glucose-Induced Vascular Smooth Muscle Cell Calcification.
    Journal of vascular research, 2015, Volume: 52, Issue:5

    Topics: Alkaline Phosphatase; Animals; Aorta; Aortic Diseases; Apoptosis; Cell Differentiation; Cells, Cultu

2015