4-phenylbutyric acid has been researched along with Aortic Aneurysm in 1 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
Aortic Aneurysm: An abnormal balloon- or sac-like dilatation in the wall of AORTA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Spinal cord ischemia was induced in rabbits by direct aortic cross-clamping (below the renal artery and above the bifurcation) for 15 minutes at normothermia." | 1.36 | Sodium 4-phenylbutyrate protects against spinal cord ischemia by inhibition of endoplasmic reticulum stress. ( Hamaishi, M; Herlambang, B; Mizukami, T; Okada, K; Orihashi, K; Sueda, T; Takahashi, S, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mizukami, T | 1 |
| Orihashi, K | 1 |
| Herlambang, B | 1 |
| Takahashi, S | 1 |
| Hamaishi, M | 1 |
| Okada, K | 1 |
| Sueda, T | 1 |
1 other study available for 4-phenylbutyric acid and Aortic Aneurysm
| Article | Year |
|---|---|
Sodium 4-phenylbutyrate protects against spinal cord ischemia by inhibition of endoplasmic reticulum stress.
Topics: Animals; Aorta, Abdominal; Aortic Aneurysm; Apoptosis; Caspase 12; Constriction; Endoplasmic Reticul | 2010 |