4-phenylbutyric acid has been researched along with Anaplastic Astrocytoma in 2 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bose, A | 1 |
| Kasle, G | 1 |
| Jana, R | 1 |
| Maulik, M | 1 |
| Thomas, D | 1 |
| Mulchandani, V | 1 |
| Mukherjee, P | 1 |
| Koval, M | 1 |
| Das Sarma, J | 1 |
| Qaisiya, M | 1 |
| Brischetto, C | 1 |
| Jašprová, J | 1 |
| Vitek, L | 1 |
| Tiribelli, C | 1 |
| Bellarosa, C | 1 |
2 other studies available for 4-phenylbutyric acid and Anaplastic Astrocytoma
| Article | Year |
|---|---|
Regulatory role of endoplasmic reticulum resident chaperone protein ERp29 in anti-murine β-coronavirus host cell response.
Topics: Animals; Astrocytoma; Brain Neoplasms; Cell Communication; Cell Line, Tumor; Connexin 43; Disease Su | 2023 |
Bilirubin-induced ER stress contributes to the inflammatory response and apoptosis in neuronal cells.
Topics: Animals; Apoptosis; Astrocytoma; Bilirubin; Caspase 3; Cell Differentiation; Cell Line, Tumor; Cell | 2017 |