4-phenylbutyric acid has been researched along with Acute Kidney Failure in 3 studies
4-phenylbutyric acid: RN refers to the parent cpd
4-phenylbutyric acid : A monocarboxylic acid the structure of which is that of butyric acid substituted with a phenyl group at C-4. It is a histone deacetylase inhibitor that displays anticancer activity. It inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. It also inhibits protein isoprenylation, depletes plasma glutamine, increases production of foetal haemoglobin through transcriptional activation of the gamma-globin gene and affects hPPARgamma activation.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| He, W | 1 |
| Qin, D | 1 |
| Li, B | 1 |
| Zhang, H | 1 |
| Cheng, X | 1 |
| Sun, J | 1 |
| Hua, J | 1 |
| Peng, S | 1 |
| Gu, Y | 1 |
| Huang, F | 1 |
| Wang, Y | 1 |
| Chen, C | 1 |
| Wu, S | 1 |
| Zhou, S | 1 |
| Hei, Z | 1 |
| Yuan, D | 1 |
| Carlisle, RE | 1 |
| Brimble, E | 1 |
| Werner, KE | 1 |
| Cruz, GL | 1 |
| Ask, K | 1 |
| Ingram, AJ | 1 |
| Dickhout, JG | 1 |
1 trial available for 4-phenylbutyric acid and Acute Kidney Failure
| Article | Year |
|---|---|
Immortalized canine adipose-derived mesenchymal stem cells alleviate gentamicin-induced acute kidney injury by inhibiting endoplasmic reticulum stress in mice and dogs.
Topics: Acute Kidney Injury; Animals; Apoptosis; Butylamines; Cells, Cultured; Culture Media; Dog Diseases; | 2021 |
2 other studies available for 4-phenylbutyric acid and Acute Kidney Failure
| Article | Year |
|---|---|
Connexin32 plays a crucial role in ROS-mediated endoplasmic reticulum stress apoptosis signaling pathway in ischemia reperfusion-induced acute kidney injury.
Topics: Acetylcysteine; Acute Kidney Injury; Animals; Apoptosis; Connexins; Endoplasmic Reticulum Chaperone | 2018 |
4-Phenylbutyrate inhibits tunicamycin-induced acute kidney injury via CHOP/GADD153 repression.
Topics: Acute Kidney Injury; Animals; Cell Line; Cytoprotection; Down-Regulation; Endoplasmic Reticulum Chap | 2014 |