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4-phenylbutyric acid, sodium salt and Muscular Atrophy, Spinal

4-phenylbutyric acid, sodium salt has been researched along with Muscular Atrophy, Spinal in 1 studies

sodium phenylbutyrate : The organic sodium salt of 4-phenylbutyric acid. A prodrug for phenylacetate, it is used to treat urea cycle disorders.

Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Xiao, J1
Marugan, JJ1
Zheng, W1
Titus, S1
Southall, N1
Cherry, JJ1
Evans, M1
Androphy, EJ1
Austin, CP1

Other Studies

1 other study available for 4-phenylbutyric acid, sodium salt and Muscular Atrophy, Spinal

ArticleYear
Discovery, synthesis, and biological evaluation of novel SMN protein modulators.
    Journal of medicinal chemistry, 2011, Sep-22, Volume: 54, Issue:18

    Topics: Alternative Splicing; Caco-2 Cells; Cell Membrane Permeability; Drug Design; Exons; Fibroblasts; Gen

2011