4-phenylbutyric acid, sodium salt has been researched along with Muscular Atrophy, Spinal in 1 studies
sodium phenylbutyrate : The organic sodium salt of 4-phenylbutyric acid. A prodrug for phenylacetate, it is used to treat urea cycle disorders.
Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Xiao, J | 1 |
Marugan, JJ | 1 |
Zheng, W | 1 |
Titus, S | 1 |
Southall, N | 1 |
Cherry, JJ | 1 |
Evans, M | 1 |
Androphy, EJ | 1 |
Austin, CP | 1 |
1 other study available for 4-phenylbutyric acid, sodium salt and Muscular Atrophy, Spinal
Article | Year |
---|---|
Discovery, synthesis, and biological evaluation of novel SMN protein modulators.
Topics: Alternative Splicing; Caco-2 Cells; Cell Membrane Permeability; Drug Design; Exons; Fibroblasts; Gen | 2011 |