4-phenyl-3-furoxancarbonitrile has been researched along with Schistosomiasis in 1 studies
4-phenyl-3-furoxancarbonitrile: structure given in first source
4-phenyl-3-furoxancarbonitrile : A 1,2,5-oxadiazole substituted by an oxido, cyano and phenyl groups at positions 2, 3 and 4, respectively. It is a vasodilator and inhibitor of platelet aggregation.
Schistosomiasis: Infection with flukes (trematodes) of the genus SCHISTOSOMA. Three species produce the most frequent clinical diseases: SCHISTOSOMA HAEMATOBIUM (endemic in Africa and the Middle East), SCHISTOSOMA MANSONI (in Egypt, northern and southern Africa, some West Indies islands, northern 2/3 of South America), and SCHISTOSOMA JAPONICUM (in Japan, China, the Philippines, Celebes, Thailand, Laos). S. mansoni is often seen in Puerto Ricans living in the United States.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Schistosomiasis is a chronic parasitic disease affecting hundreds of millions of individuals worldwide." | 1.35 | Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis. ( Arnér, ES; Austin, CP; Chakrapani, H; Inglese, J; Jadhav, A; Keefer, L; Lea, WA; Leister, W; Luecke, HF; Maloney, DJ; Prast-Nielsen, S; Rai, G; Sayed, AA; Shen, M; Simeonov, A; Thomas, CJ; Williams, DL, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rai, G | 1 |
| Sayed, AA | 1 |
| Lea, WA | 1 |
| Luecke, HF | 1 |
| Chakrapani, H | 1 |
| Prast-Nielsen, S | 1 |
| Jadhav, A | 1 |
| Leister, W | 1 |
| Shen, M | 1 |
| Inglese, J | 1 |
| Austin, CP | 1 |
| Keefer, L | 1 |
| Arnér, ES | 1 |
| Simeonov, A | 1 |
| Maloney, DJ | 1 |
| Williams, DL | 1 |
| Thomas, CJ | 1 |
1 other study available for 4-phenyl-3-furoxancarbonitrile and Schistosomiasis
| Article | Year |
|---|---|
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis.
Topics: Animals; Biological Availability; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentratio | 2009 |