4-oxo-4-(3-pyridyl)butanoic acid and Poliomyelitis

4-oxo-4-(3-pyridyl)butanoic acid has been researched along with Poliomyelitis in 1 studies

4-oxo-4-(3-pyridyl)butanoic acid: structure in first source
4-oxo-4-(pyridin-3-yl)butanoic acid : A monocarboxylic acid that is succinic acid in which the hydroxy group of one of the carboxy groups is replaced by a pyridin-3-yl group. A byproduct of tobacco-specific N-nitrosamines generated by cytochrome P-450 which catalyzes methylnitrosaminopyridylbutanone hydroxylation, this nicotine metabolite is commonly found in the urine of smokers.

Poliomyelitis: An acute infectious disease of humans, particularly children, caused by any of three serotypes of human poliovirus (POLIOVIRUS). Usually the infection is limited to the gastrointestinal tract and nasopharynx, and is often asymptomatic. The central nervous system, primarily the spinal cord, may be affected, leading to rapidly progressive paralysis, coarse FASCICULATION and hyporeflexia. Motor neurons are primarily affected. Encephalitis may also occur. The virus replicates in the nervous system, and may cause significant neuronal loss, most notably in the spinal cord. A rare related condition, nonpoliovirus poliomyelitis, may result from infections with nonpoliovirus enteroviruses. (From Adams et al., Principles of Neurology, 6th ed, pp764-5)

Research

Studies (1)

Authors

Other Studies

1 other study available for 4-oxo-4-(3-pyridyl)butanoic acid and Poliomyelitis