4-nitroquinoline-1-oxide has been researched along with Malignant Melanoma in 8 studies
4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this study, we performed both assays in 16 established lymphoblastoid cell lines derived from patients with xeroderma pigmentosum (n = 3), ataxia telangiectasia (n = 2), head and neck cancer (n = 3), and melanoma (n = 2), and from normal human subjects (n = 6) using UV light, 4-nitroquinoline-1-oxide (4-NQO; an UV-mimetic agent), and gamma-irradiation as the test agents." | 3.69 | DNA repair capacity correlates with mutagen sensitivity in lymphoblastoid cell lines. ( Cheng, L; Gu, J; Hsu, TC; Kripke, ML; Spitz, MR; Strom, SS; Wei, Q; Xu, X, 1996) |
| "Lymphoblastoid cell lines established from three unrelated kindreds with familial melanoma (FM) were cytogenetically analyzed for spontaneous and 4-nitroquinoline-1-oxide (4NQO)-induced chromosome aberrations." | 3.67 | Spontaneous and 4-nitroquinoline 1-oxide-induced G2 chromosome aberrations in lymphoblasts from familial melanoma patients. ( Hayward, NK; Lu, GH; Stanley, WS, 1989) |
| " Dose-response relationships were evident in both studies when the data were categorized by quartiles of breaks/cell in the controls, with highest risk estimates being in the top quartile of induced breaks." | 1.29 | Mutagen sensitivity exhibits a dose-response relationship in case-control studies. ( Hsu, TC; Spitz, MR; Wu, X, 1996) |
| "The dysplastic nevus syndrome (DNS) is a preneoplastic melanocyte abnormality which occurs in families affected by hereditary cutaneous malignant melanoma (HCMM)." | 1.27 | Abnormal responses to the carcinogen 4-nitroquinoline 1-oxide of cultured fibroblasts from patients with dysplastic nevus syndrome and hereditary cutaneous malignant melanoma. ( Adams, D; Greene, MH; Paterson, MC; Smith, PJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, LE | 1 |
| Li, C | 1 |
| Xiong, P | 1 |
| Gershenwald, JE | 1 |
| Prieto, VG | 1 |
| Duvic, M | 1 |
| Lee, JE | 1 |
| Grimm, EA | 1 |
| Hsu, TC | 3 |
| Wei, Q | 2 |
| Lobikin, M | 1 |
| Chernet, B | 1 |
| Lobo, D | 1 |
| Levin, M | 1 |
| Smith, PJ | 1 |
| Greene, MH | 3 |
| Adams, D | 1 |
| Paterson, MC | 1 |
| Howell, JN | 2 |
| Corner, RC | 1 |
| Maher, VM | 2 |
| McCormick, JJ | 2 |
| Wu, X | 1 |
| Spitz, MR | 2 |
| Gu, J | 1 |
| Cheng, L | 1 |
| Xu, X | 1 |
| Strom, SS | 1 |
| Kripke, ML | 1 |
| Lu, GH | 1 |
| Hayward, NK | 1 |
| Stanley, WS | 1 |
| Sato, K | 1 |
8 other studies available for 4-nitroquinoline-1-oxide and Malignant Melanoma
| Article | Year |
|---|---|
4-nitroquinoline-1-oxide-induced mutagen sensitivity and risk of cutaneous melanoma: a case-control analysis.
Topics: 4-Nitroquinoline-1-oxide; Adult; Case-Control Studies; Dose-Response Relationship, Drug; Female; Hum | 2016 |
Resting potential, oncogene-induced tumorigenesis, and metastasis: the bioelectric basis of cancer in vivo.
Topics: 4-Nitroquinoline-1-oxide; Animals; Blood Vessels; Body Patterning; Carcinogens; Cell Transformation, | 2012 |
Abnormal responses to the carcinogen 4-nitroquinoline 1-oxide of cultured fibroblasts from patients with dysplastic nevus syndrome and hereditary cutaneous malignant melanoma.
Topics: 4-Nitroquinoline-1-oxide; Cell Line; Cell Survival; Cells, Cultured; DNA Repair; DNA Replication; Fi | 1983 |
Fibroblasts from patients with hereditary cutaneous malignant melanoma are abnormally sensitive to the mutagenic effect of simulated sunlight and 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Adult; Cells, Cultured; Dose-Response Relationship, Radiation; Female; Fib | 1984 |
Mutagen sensitivity exhibits a dose-response relationship in case-control studies.
Topics: 4-Nitroquinoline-1-oxide; Antibiotics, Antineoplastic; Bleomycin; Case-Control Studies; Cell Culture | 1996 |
DNA repair capacity correlates with mutagen sensitivity in lymphoblastoid cell lines.
Topics: 4-Nitroquinoline-1-oxide; Ataxia Telangiectasia; Biomarkers; Carcinogens; Cell Line; Chromatids; Chr | 1996 |
Spontaneous and 4-nitroquinoline 1-oxide-induced G2 chromosome aberrations in lymphoblasts from familial melanoma patients.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Aberrations; Humans; Interphase; Lymphocytes; Melanoma; Neoplas | 1989 |
Relationship between sensitivity of cells from patients with hereditary cutaneous malignant melanoma to killing and mutations by 4-nitroquinoline 1-oxide and adduct formation.
Topics: 4-Nitroquinoline-1-oxide; Cell Line; Cell Survival; Dysplastic Nevus Syndrome; Humans; Male; Melanom | 1988 |