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4-nitroquinoline-1-oxide and Hepatocellular Carcinoma

4-nitroquinoline-1-oxide has been researched along with Hepatocellular Carcinoma in 4 studies

4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.

Research Excerpts

ExcerptRelevanceReference
"Among eight ascites hepatoma cell lines, AH-13 was extremely sensitive both to in vivo antitumor and to in vitro lethal action of the agent, whereas AH-44 was resistant in both cases."1.26Suggestive evidence for relationship between sensitivity and repair capability in rat ascites hepatoma cells treated with the antitumor agent, 1-(gamma-chloropropyl)-2-chloromethylpiperidine hydrobromide. ( Fukuda, S; Hatano, M; Koshiura, R; Miyamoto, K, 1977)
"among rat liver cells untreated, hepatoma cells produced by back-transplantation of rat liver cells after the treatment with a chemical carcinogen in tissue culture, and the hepatoma cells passaged serially through rats."1.25Carcinogenesis in tissue culture 24: tumorigenicity and aggregate-forming capacity of mammalian cells in culture. ( Akatsuka, T; Katsuta, H; Takaoka, T, 1975)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Valentin-Severin, I1
Le Hegarat, L1
Lhuguenot, JC1
Le Bon, AM1
Chagnon, MC1
Morrow, CS1
Smitherman, PK1
Townsend, AJ1
Takaoka, T1
Katsuta, H1
Akatsuka, T1
Fukuda, S1
Koshiura, R1
Miyamoto, K1
Hatano, M1

Other Studies

4 other studies available for 4-nitroquinoline-1-oxide and Hepatocellular Carcinoma

ArticleYear
Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays.
    Mutation research, 2003, Apr-20, Volume: 536, Issue:1-2

    Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Carcinoma, Hepatocellular; Comet As

2003
Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cells.
    Molecular carcinogenesis, 2000, Volume: 29, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; ATP Binding Cassette Transporter, Subfamily B; Carcinogens; Carcinoma, Hep

2000
Carcinogenesis in tissue culture 24: tumorigenicity and aggregate-forming capacity of mammalian cells in culture.
    The Japanese journal of experimental medicine, 1975, Volume: 45, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Hepatocellular; Cell Aggregation; Cell Nucleolus; Cell

1975
Suggestive evidence for relationship between sensitivity and repair capability in rat ascites hepatoma cells treated with the antitumor agent, 1-(gamma-chloropropyl)-2-chloromethylpiperidine hydrobromide.
    Gan, 1977, Volume: 68, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Hepatocellular; Cell Line; DNA Repair; DNA, Bacterial;

1977