4-nitroquinoline-1-oxide has been researched along with Genetic Predisposition in 14 studies
4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Susceptibly to the induction of rat tongue cancer (TC) by oral 4-nitroquinoline 1-oxide (4NQO) exposure is a polygenic trait." | 1.40 | Pthlh, a promising cancer modifier gene in rat tongue carcinogenesis. ( Ehara, M; Hiai, H; Hirano, M; Kawarada, K; Kitano, M; Muraki, T; Nagayama, M; Shisa, H; Sugimoto, M; Sugiyama, A; Suwa, H; Tanuma, J, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 9 (64.29) | 29.6817 |
| 2010's | 4 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suwa, H | 1 |
| Hirano, M | 4 |
| Kawarada, K | 1 |
| Nagayama, M | 1 |
| Ehara, M | 1 |
| Muraki, T | 1 |
| Shisa, H | 4 |
| Sugiyama, A | 1 |
| Sugimoto, M | 1 |
| Hiai, H | 3 |
| Kitano, M | 5 |
| Tanuma, J | 3 |
| Wu, X | 2 |
| Zheng, YL | 1 |
| Hsu, TC | 2 |
| Li, C | 1 |
| Wang, LE | 1 |
| Wei, Q | 1 |
| Wilkey, JF | 1 |
| Buchberger, G | 1 |
| Saucier, K | 1 |
| Patel, SM | 1 |
| Eisenberg, E | 1 |
| Nakagawa, H | 1 |
| Michaylira, CZ | 1 |
| Rustgi, AK | 1 |
| Mallya, SM | 1 |
| Morrison, BH | 1 |
| Haney, R | 1 |
| Lamarre, E | 1 |
| Drazba, J | 1 |
| Prestwich, GD | 1 |
| Lindner, DJ | 1 |
| Naoi, K | 1 |
| Sunagawa, N | 1 |
| Yoshida, I | 1 |
| Morioka, T | 1 |
| Nakashima, M | 1 |
| Ishihara, M | 1 |
| Fukamachi, K | 1 |
| Itoh, Y | 1 |
| Tsuda, H | 1 |
| Yoshimi, N | 1 |
| Suzui, M | 1 |
| Park, JW | 1 |
| Pitot, HC | 1 |
| Strati, K | 1 |
| Spardy, N | 1 |
| Duensing, S | 1 |
| Grompe, M | 1 |
| Lambert, PF | 1 |
| Hirayama, Y | 2 |
| Ohyama, M | 1 |
| Semba, I | 2 |
| Wakusawa, S | 1 |
| Ogawa, K | 1 |
| Fong, LY | 1 |
| Jiang, Y | 1 |
| Farber, JL | 1 |
| Zhang, Z | 1 |
| Wang, Y | 1 |
| Yao, R | 1 |
| Li, J | 1 |
| Lubet, RA | 1 |
| You, M | 1 |
| Gu, J | 1 |
| Bondy, ML | 1 |
| Sigurdson, A | 1 |
| Spitz, MR | 1 |
| Tanuma, JI | 1 |
| Fujii, K | 1 |
| Matsuuchi, H | 1 |
2 reviews available for 4-nitroquinoline-1-oxide and Genetic Predisposition
| Article | Year |
|---|---|
DNA repair phenotype and cancer susceptibility--a mini review.
Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; DNA Adducts; DNA Repai | 2009 |
Host genes controlling the susceptibility and resistance to squamous cell carcinoma of the tongue in a rat model.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Carcinoma, Squamous Cell; Chromosome Mapping; Geneti | 2000 |
12 other studies available for 4-nitroquinoline-1-oxide and Genetic Predisposition
| Article | Year |
|---|---|
Pthlh, a promising cancer modifier gene in rat tongue carcinogenesis.
Topics: 4-Nitroquinoline-1-oxide; Animals; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Gene | 2014 |
Mutagen sensitivity as measured by induced chromatid breakage as a marker of cancer risk.
Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bleomycin; Cells, Cult | 2014 |
Cyclin D1 overexpression increases susceptibility to 4-nitroquinoline-1-oxide-induced dysplasia and neoplasia in murine squamous oral epithelium.
Topics: 4-Nitroquinoline-1-oxide; Animals; Blotting, Northern; Carcinogens; Cell Differentiation; Cell Proli | 2009 |
Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma.
Topics: 4-Nitroquinoline-1-oxide; Animals; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; Esophageal Neop | 2009 |
Enhancement of tongue carcinogenesis in Hras128 transgenic rats treated with 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Drug S | 2010 |
Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer.
Topics: 4-Nitroquinoline-1-oxide; Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; DNA Damage; Fanconi | 2010 |
A speed congenic rat strain bearing the tongue cancer susceptibility locus Tscc1 from Dark-Agouti rats.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Carcinoma, Squamous Cell; Chromosomes; Female; Genet | 2006 |
Selective loss of resistant alleles at p15INK4B and p16INK4A genes in chemically-induced rat tongue cancers.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Cyclin-Dependent Kinase Inhibitor p15; DNA Methylati | 2006 |
Zinc deficiency potentiates induction and progression of lingual and esophageal tumors in p53-deficient mice.
Topics: 4-Nitroquinoline-1-oxide; Animals; Biomarkers, Tumor; Carcinogens; Cyclooxygenase 2; Disease Models, | 2006 |
p53 Transgenic mice are highly susceptible to 4-nitroquinoline-1-oxide-induced oral cancer.
Topics: 4-Nitroquinoline-1-oxide; Animals; Apoptosis; Carcinogens; Carcinoma, Squamous Cell; Cell Cycle; Dis | 2006 |
Three measures of mutagen sensitivity in a cancer-free population.
Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Bleomycin | 1999 |
Five quantitative trait loci affecting 4-nitroquinoline 1-oxide-induced tongue cancer in the rat.
Topics: 4-Nitroquinoline-1-oxide; Alleles; Animals; Carcinogens; Chromosome Mapping; Female; Genetic Predisp | 2001 |