4-nitroquinoline-1-oxide has been researched along with Fanconi Anemia in 5 studies
4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.
Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In order to develop the usefulness of Fanconi's anemia (FA) lymphoblast lines for biochemical and genetic studies, we have determined their sensitivity to a variety of DNA-damaging chemicals." | 1.26 | Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents. ( Buchwald, M; Ishida, R, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Park, JW | 1 |
| Pitot, HC | 1 |
| Strati, K | 1 |
| Spardy, N | 1 |
| Duensing, S | 1 |
| Grompe, M | 1 |
| Lambert, PF | 1 |
| Morimoto, K | 1 |
| Miura, K | 1 |
| Kaneko, T | 1 |
| Iijima, K | 1 |
| Sato, M | 1 |
| Koizumi, A | 1 |
| Ishida, R | 1 |
| Buchwald, M | 1 |
| Jones, NJ | 1 |
| Ellard, S | 1 |
| Waters, R | 1 |
| Parry, EM | 1 |
| Gebhart, E | 1 |
| Kysela, D | 1 |
| Matthee, H | 1 |
| Nikol, M | 1 |
5 other studies available for 4-nitroquinoline-1-oxide and Fanconi Anemia
| Article | Year |
|---|---|
Deficiencies in the Fanconi anemia DNA damage response pathway increase sensitivity to HPV-associated head and neck cancer.
Topics: 4-Nitroquinoline-1-oxide; Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell; DNA Damage; Fanconi | 2010 |
Human health situation and chromosome alterations: sister chromatid exchange frequency in lymphocytes from passive smokers and patients with hereditary diseases.
Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Alzheimer Disease; Anemia, Aplastic; Cell Cycle; Cells, | 1984 |
Susceptibility of Fanconi's anemia lymphoblasts to DNA-cross-linking and alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Anemia, Aplastic; Antibiotics, Antineoplastic; Carcinog | 1982 |
Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: phenotypic similarities to ataxia telangiectasia and Fanconi's anaemia cells.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Animals; Ataxia Telangiectasia; Cell Line; Cell Surviva | 1993 |
Cytogenetic analyses utilizing various clastogens in two sibs with Fanconi anemia, their relatives, and control individuals.
Topics: 4-Nitroquinoline-1-oxide; Adult; Anemia, Aplastic; Bromodeoxyuridine; Cells, Cultured; Child; Child, | 1985 |