4-nitroquinoline-1-oxide has been researched along with Experimental Neoplasms in 85 studies
4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| " One week after starting propranolol treatment, all rats were submitted to chemical induction of oral carcinogenesis with 4-nitroquinoline-1-oxide (4NQO)." | 3.96 | Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion. ( Bernabé, DG; Biasoli, ÉR; Cecilio, HP; Furuse, C; Kayahara, GM; Miyahara, GI; Oliveira, SHP; Pereira, KM; Valente, VB, 2020) |
| "The mutant mouse lymphoma cell Q31, which is sensitive to 4-nitroquinoline 1-oxide and ultraviolet radiation (UV), was compared with the parental L5178Y cell for the effect of caffeine and mutation induction after UV irradiation." | 3.66 | Mutation induction in a mouse lymphoma cell mutant sensitive to 4-nitroquinoline 1-oxide and ultraviolet radiation. ( Hieda, N; Sato, K, 1980) |
| "The role of CD44 in progression of head and neck squamous cell carcinoma (HNSCC) has been controversial." | 1.51 | CD44(+) tumor cells promote early angiogenesis in head and neck squamous cell carcinoma. ( Azambuja, JH; Dolg, L; Gellrich, NC; Gluszko, A; Kampmann, A; Ludwig, N; Szafarowski, T; Szczepanski, MJ; Whiteside, TL; Zimmerer, RM, 2019) |
| "This carcinogenesis model was quantitatively evaluated by FI." | 1.51 | Method for diagnosing neoplastic lesions by quantitative fluorescence value. ( Kasahara, M; Kosugi, A; Mori, T; Nakamura-Takahashi, A; Shibahara, T; Yang, L, 2019) |
| "Advanced oral squamous cell carcinomas (OSCC) have limited therapeutic options." | 1.51 | Impact of combination immunochemotherapies on progression of 4NQO-induced murine oral squamous cell carcinoma. ( Chelvanambi, M; Fabian, KPL; Hong, CS; Lang, S; Ludwig, S; Razzo, BM; Storkus, WJ; Whiteside, TL, 2019) |
| "The majority of cases of oral squamous cell carcinoma (OSCC) develop from oral potentially malignant disorders, which have been confirmed to be involved in chronic oxidative stimulation." | 1.48 | Proteomics-based investigation of multiple stages of OSCC development indicates that the inhibition of Trx-1 delays oral malignant transformation. ( Chen, X; Cheng, B; Hu, Q; Wang, C; Wu, T; Xia, J; Yang, L, 2018) |
| "The incidence of extraoral neoplasms was significantly lower (16%) in the younger cohort." | 1.48 | Impact of Age on Disease Progression and Microenvironment in Oral Cancer. ( DeJong, H; Hershberger, PA; Merzianu, M; Patti, A; Rich, LJ; Seshadri, M; Vincent-Chong, VK, 2018) |
| "The incidence of animals developing squamous cell carcinomas was similar in both groups, but tumour development was significantly earlier in iron-deficient animals (mean 183 days) compared to controls (mean 229 days)." | 1.27 | The effect of iron deficiency on experimental oral carcinogenesis in the rat. ( MacDonald, DG; Prime, SS; Rennie, JS, 1983) |
| "Oral epithelial atypia and squamous cell carcinoma were observed with increasing prevalence as the period of carcinogen exposure was increased." | 1.27 | Experimental induction of oral squamous cell carcinomas in mice with 4-nitroquinolone-1-oxide. ( Reade, PC; Steidler, NE, 1984) |
| "Invasive carcinomas were either endophytic or exophytic." | 1.27 | Experimental tongue carcinoma of rats induced by oral administration of 4-nitroquinoline 1-oxide (4NQO) in drinking water. ( Ohne, M; Satoh, T; Takai, H; Yamada, S, 1985) |
| "The clinical development of oral cancer differed significantly among the three groups (P less than 0." | 1.26 | Effect of different levels of dietary zinc on development of chemically induced oral cancer in rats. ( Abdulla, M; Mathur, A; Wallenius, K, 1979) |
| "Among eight ascites hepatoma cell lines, AH-13 was extremely sensitive both to in vivo antitumor and to in vitro lethal action of the agent, whereas AH-44 was resistant in both cases." | 1.26 | Suggestive evidence for relationship between sensitivity and repair capability in rat ascites hepatoma cells treated with the antitumor agent, 1-(gamma-chloropropyl)-2-chloromethylpiperidine hydrobromide. ( Fukuda, S; Hatano, M; Koshiura, R; Miyamoto, K, 1977) |
| "Xerostomia was induced in 15 rats and 4NQO was applied to the palate 3 times a week." | 1.26 | Experimental oral cancer in rats with xerostomia. ( Lekholm, U; Wallenius, K, 1976) |
| "Two were classified as squamous cell carcinoma, one was as a leiomyosarcoma and the other two were undifferentiated sarcoma." | 1.26 | Electron microscopic studies of placental and uterine tumors induced in rats. ( Kakudo, K; Miyaji, T; Onishi, S; Sugaya, T, 1976) |
| "among rat liver cells untreated, hepatoma cells produced by back-transplantation of rat liver cells after the treatment with a chemical carcinogen in tissue culture, and the hepatoma cells passaged serially through rats." | 1.25 | Carcinogenesis in tissue culture 24: tumorigenicity and aggregate-forming capacity of mammalian cells in culture. ( Akatsuka, T; Katsuta, H; Takaoka, T, 1975) |
| "A high incidence of squamous cell carcinomas of the forestomach was found in groups 4 and 5." | 1.25 | Effects in rats of sodium chloride on experimental gastric cancers induced by N-methyl-N-nitro-N-nitrosoguanidine or 4-nitroquinoline-1-oxide. ( Fukushima, S; Hananouchi, M; Shirai, T; Takahashi, M; Tatematsu, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 64 (75.29) | 18.7374 |
| 1990's | 7 (8.24) | 18.2507 |
| 2000's | 4 (4.71) | 29.6817 |
| 2010's | 8 (9.41) | 24.3611 |
| 2020's | 2 (2.35) | 2.80 |
| Authors | Studies |
|---|---|
| Li, JH | 1 |
| Forghani, R | 1 |
| Bure, L | 1 |
| Wojtkiewicz, GR | 1 |
| Wu, Y | 1 |
| Iwamoto, Y | 1 |
| Ali, M | 1 |
| Li, A | 1 |
| Wang, C | 2 |
| Jalali Motlagh, N | 1 |
| Papadakis, AI | 1 |
| Pusztaszeri, MP | 1 |
| Spatz, A | 1 |
| Curtin, H | 1 |
| Cheng, YS | 1 |
| Chen, JW | 1 |
| Ludwig, N | 1 |
| Szczepanski, MJ | 1 |
| Gluszko, A | 1 |
| Szafarowski, T | 1 |
| Azambuja, JH | 1 |
| Dolg, L | 1 |
| Gellrich, NC | 1 |
| Kampmann, A | 1 |
| Whiteside, TL | 2 |
| Zimmerer, RM | 1 |
| Cecilio, HP | 1 |
| Valente, VB | 1 |
| Pereira, KM | 1 |
| Kayahara, GM | 1 |
| Furuse, C | 1 |
| Biasoli, ÉR | 1 |
| Miyahara, GI | 1 |
| Oliveira, SHP | 1 |
| Bernabé, DG | 1 |
| Mohan, S | 1 |
| Thiagarajan, K | 1 |
| Chandrasekaran, R | 1 |
| Chen, X | 2 |
| Hu, Q | 1 |
| Wu, T | 1 |
| Xia, J | 1 |
| Yang, L | 2 |
| Cheng, B | 1 |
| Vincent-Chong, VK | 1 |
| DeJong, H | 1 |
| Rich, LJ | 1 |
| Patti, A | 1 |
| Merzianu, M | 1 |
| Hershberger, PA | 1 |
| Seshadri, M | 1 |
| Kosugi, A | 1 |
| Kasahara, M | 1 |
| Nakamura-Takahashi, A | 1 |
| Shibahara, T | 1 |
| Mori, T | 1 |
| Ludwig, S | 1 |
| Hong, CS | 1 |
| Razzo, BM | 1 |
| Fabian, KPL | 1 |
| Chelvanambi, M | 1 |
| Lang, S | 1 |
| Storkus, WJ | 1 |
| Chen, YF | 1 |
| Chang, KW | 1 |
| Yang, IT | 1 |
| Tu, HF | 1 |
| Lin, SC | 1 |
| Fracalossi, AC | 1 |
| Comparini, L | 1 |
| Funabashi, K | 1 |
| Godoy, C | 1 |
| Iwamura, ES | 1 |
| Nascimento, FD | 1 |
| Nader, HB | 1 |
| Oshima, CT | 1 |
| Ribeiro, DA | 1 |
| TAKAYAMA, S | 5 |
| ENDO, H | 1 |
| AOKI, M | 1 |
| AOYAMA, Y | 1 |
| OOTA, K | 1 |
| SHIRASU, Y | 1 |
| SEARLE, CE | 2 |
| WOODHOUSE, DL | 2 |
| MORI, K | 5 |
| HIRAFUKU, I | 1 |
| AZUMA, N | 1 |
| DAN, R | 1 |
| KABAYAMA, M | 1 |
| KODAMA, K | 1 |
| IKENOUE, K | 1 |
| NISHIZUKA, Y | 1 |
| NAKAKUKI, K | 1 |
| SAKAKURA, T | 1 |
| HISAMATSU, T | 1 |
| OKAMOTO, K | 1 |
| HAYASHI, Y | 2 |
| MOORE, PR | 1 |
| MANNERING, GJ | 1 |
| TEPLY, LJ | 1 |
| KLINE, BE | 1 |
| Nomura, T | 6 |
| Nakajima, H | 1 |
| Ryo, H | 1 |
| Li, LY | 1 |
| Fukudome, Y | 1 |
| Adachi, S | 1 |
| Gotoh, H | 2 |
| Tanaka, H | 2 |
| Choi, Y | 1 |
| Kim, SY | 1 |
| Park, K | 1 |
| Yang, J | 1 |
| Cho, KJ | 1 |
| Kwon, HJ | 1 |
| Byun, Y | 1 |
| Kokubo, T | 1 |
| Takahashi, M | 3 |
| Kurokawa, Y | 1 |
| Miyahara, M | 1 |
| Furihata, C | 1 |
| Matsushima, T | 2 |
| Prime, SS | 2 |
| MacDonald, DG | 1 |
| Rennie, JS | 1 |
| Philipsen, HP | 2 |
| Fisker, AV | 3 |
| Hama-Inaba, H | 1 |
| Hieda-Shiomi, N | 1 |
| Shiomi, T | 1 |
| Sato, K | 4 |
| Mitani, H | 1 |
| Kondo, S | 1 |
| Wong, PN | 1 |
| Wilson, DF | 1 |
| Steidler, NE | 1 |
| Reade, PC | 1 |
| Hieda, N | 2 |
| Ito, N | 2 |
| Jones, RT | 1 |
| Hudson, EA | 1 |
| Resau, JH | 1 |
| Ohne, M | 3 |
| Takaki, T | 2 |
| Sekigawa, K | 2 |
| Mochizuki, A | 2 |
| Sakurada, Y | 2 |
| Kobayashi, A | 2 |
| Omori, K | 2 |
| Tachikawa, T | 2 |
| Muramatsu, H | 2 |
| Nagai, Y | 2 |
| Kojo, U | 2 |
| Kuboyama, N | 1 |
| Fujii, A | 1 |
| Tamura, T | 1 |
| Eveson, JW | 2 |
| Smith, BL | 1 |
| Sager, R | 1 |
| Hirao, F | 2 |
| Yoshimoto, T | 2 |
| Namba, M | 2 |
| Svensson, S | 1 |
| Heyden, G | 2 |
| Okamoto, E | 1 |
| Namba, T | 1 |
| Sakamoto, Y | 1 |
| Yamamoto, S | 1 |
| Mitsumori, K | 1 |
| Kodama, Y | 1 |
| Matsunuma, N | 1 |
| Manabe, S | 1 |
| Okamiya, H | 1 |
| Suzuki, H | 1 |
| Fukuda, T | 1 |
| Sakamaki, Y | 1 |
| Sunaga, M | 1 |
| Nomura, G | 1 |
| Hioki, K | 1 |
| Wakana, S | 1 |
| Tanaka, T | 3 |
| Makita, H | 2 |
| Ohnishi, M | 1 |
| Mori, H | 2 |
| Satoh, K | 1 |
| Hara, A | 1 |
| Sumida, T | 1 |
| Fukutani, K | 1 |
| Ogawa, H | 1 |
| Kawabata, K | 1 |
| El-Bayoumy, K | 1 |
| Kino, K | 1 |
| Fushimi, K | 1 |
| Gao, C | 1 |
| Shima, T | 1 |
| Mihara, K | 1 |
| Takasaki, M | 1 |
| Konoshima, T | 1 |
| Etoh, H | 1 |
| Pal Singh, I | 1 |
| Tokuda, H | 1 |
| Nishino, H | 1 |
| Robinson, CM | 1 |
| Huntley, S | 1 |
| Stone, AM | 1 |
| Davies, M | 1 |
| Paterson, IC | 1 |
| Altanerová, V | 1 |
| Higuchi, M | 1 |
| Ghosh, BC | 1 |
| Ghosh, L | 1 |
| Newson, BL | 1 |
| Das Gupta, TK | 1 |
| Nishikawa, H | 1 |
| Yasaki, S | 1 |
| Ogura, T | 1 |
| Azuma, I | 1 |
| Taniyama, T | 1 |
| Kishimoto, S | 1 |
| Yamamura, Y | 1 |
| Takahashi, K | 1 |
| Kawazoe, Y | 1 |
| Tada, M | 2 |
| Okada, M | 1 |
| Wallenius, K | 4 |
| Mathur, A | 2 |
| Abdulla, M | 2 |
| Takaoka, T | 1 |
| Katsuta, H | 1 |
| Akatsuka, T | 1 |
| Fukuda, S | 1 |
| Koshiura, R | 1 |
| Miyamoto, K | 1 |
| Hatano, M | 1 |
| Kakunaga, T | 1 |
| Lekholm, U | 2 |
| Horikoshi, T | 1 |
| Tatematsu, M | 2 |
| Fukushima, S | 1 |
| Hananouchi, M | 2 |
| Shirai, T | 1 |
| Klaer, HW | 1 |
| Glavind, J | 1 |
| Arffmann, E | 1 |
| Hoshino, H | 1 |
| Tanooka, H | 1 |
| Stein, GH | 1 |
| Nagao, M | 1 |
| Sugimura, T | 1 |
| Yamaguchi, Z | 1 |
| Hirose, M | 1 |
| Kinoshita, H | 1 |
| Kakudo, K | 1 |
| Sugaya, T | 1 |
| Onishi, S | 1 |
| Miyaji, T | 1 |
| Katoh, Y | 1 |
| Johansson, SL | 1 |
| Hirsch, JM | 1 |
| Larsson, PA | 1 |
| Saidi, J | 1 |
| Osterdahl, BG | 1 |
| West, MJ | 1 |
| Andersen, AH | 1 |
| Satoh, T | 1 |
| Yamada, S | 1 |
| Takai, H | 1 |
7 reviews available for 4-nitroquinoline-1-oxide and Experimental Neoplasms
| Article | Year |
|---|---|
Transgenerational transmission of radiation- and chemically induced tumors and congenital anomalies in mice: studies of their possible relationship to induced chromosomal and molecular changes.
Topics: 4-Nitroquinoline-1-oxide; Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Ca | 2004 |
In vivo carcinogenesis of 4-nitroquinoline 1-oxide and related compounds.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Esophageal Neoplasms; Intestinal Neoplasms; Liver Ne | 1981 |
A review of in vitro and in vivo culture techniques for the study of pancreatic carcinogenesis.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Cattle; Cells, Cultured; Cricetinae; Culture Media; | 1981 |
Animal models of intra-oral chemical carcinogenesis: a review.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animal Nutritional Physiological Phenome | 1981 |
[In vivo fate of environmental carcinogens (author's transl)].
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Animals; Benzopyrenes; Carcinogens, Environmental; | 1978 |
Molecular biology of the carcinogen, 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Animals; Bacteria; Bacteriophages; Base Sequence; Carcinogens; Ce | 1976 |
Experimental oral carcinogenesis. A basic rat model for the study of oral carcinogenesis using the carcinogen 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Disease Models, Animal; Dose-Re | 1990 |
78 other studies available for 4-nitroquinoline-1-oxide and Experimental Neoplasms
| Article | Year |
|---|---|
Molecular immuno-imaging improves tumor detection in head and neck cancer.
Topics: 4-Nitroquinoline-1-oxide; Animals; Biomarkers, Tumor; Cell Line, Tumor; Female; Head and Neck Neopla | 2022 |
CD44(+) tumor cells promote early angiogenesis in head and neck squamous cell carcinoma.
Topics: 4-Nitroquinoline-1-oxide; Animals; Case-Control Studies; Cell Line, Tumor; Female; Gene Expression P | 2019 |
Beta-adrenergic blocker inhibits oral carcinogenesis and reduces tumor invasion.
Topics: 4-Nitroquinoline-1-oxide; Adrenergic beta-Antagonists; Animals; Carcinogenesis; Carcinogens; Cytokin | 2020 |
Evaluation of ethyl gallate for its antioxidant and anticancer properties against chemical-induced tongue carcinogenesis in mice.
Topics: 4-Nitroquinoline-1-oxide; Acacia; Animals; Antineoplastic Agents, Phytogenic; Antioxidants; Carcinom | 2017 |
Proteomics-based investigation of multiple stages of OSCC development indicates that the inhibition of Trx-1 delays oral malignant transformation.
Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Animals; Apoptosis; Biomarkers, Tumor; Carcinogenesis; Carcin | 2018 |
Impact of Age on Disease Progression and Microenvironment in Oral Cancer.
Topics: 4-Nitroquinoline-1-oxide; Age Factors; Animals; Carcinoma, Squamous Cell; Disease Progression; Femal | 2018 |
Method for diagnosing neoplastic lesions by quantitative fluorescence value.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Disease Pr | 2019 |
Impact of combination immunochemotherapies on progression of 4NQO-induced murine oral squamous cell carcinoma.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; | 2019 |
Establishment of syngeneic murine model for oral cancer therapy.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents; B7-H1 Antigen; Carcinogenesis; Carcinogens | 2019 |
Ras gene mutation is not related to tumour invasion during rat tongue carcinogenesis induced by 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Actins; Animals; Cell Transformation, Neoplastic; Genes, ras; Ki-67 Antige | 2011 |
Effect of 4-nitroquinoline N-oxide painting on azo dye hepatocarcinogenesis in rats, with note on induction of skin fibrosarcoma.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azo Compounds; Carcinogens; Coloring Agents; Fibrosarcoma; Liver | 1961 |
Formation of nuclear inclusion bodies in tissue culture cells by 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Intranuclear Inclusion Bodies; Neoplasms, Experiment | 1959 |
Skin carcinogenesis with a single painting of 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogenesis; Carcinogens; Neoplasms, Experimental; Oxides; Pai | 1960 |
Correlative histochemical and autoradiographical studies on the mouse skin after the painting with tritium labeled 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Autoradiography; Carcinogens; Mice; Neoplasms, Experimental; Oxid | 1961 |
Carcinogenic action of 6-chloro-4-nitroquinoline 1-oxide on the rat skin.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Neoplasms, Experimental; Oxides; Quinolines; Rats | 1962 |
A carcinogenic experiment with 4-nitroquinoline 1-oxide in guinea pig.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Guinea Pigs; Neoplasms; Neoplasms, Experimental; Oxi | 1962 |
THE CARCINOGENICITY AND REACTIVITY TO TISSUE CONSTITUENTS OF 4-NITROQUINOLINE-N-OXIDE.
Topics: 4-Nitroquinoline-1-oxide; Animals; Benzopyrenes; Guinea Pigs; Liver; Metabolism; Mice; Neoplasms; Ne | 1963 |
4-NITROQUINOLINE N-OXIDE: AN INHIBITOR OF BENZPYRENE CARCINOGENESIS OF MOUSE SKIN.
Topics: 4-Nitroquinoline-1-oxide; Animals; Benzopyrenes; Carcinogenesis; Carcinogens; Mice; Neoplasms; Neopl | 1964 |
HISTOGENESIS OF LUNG CARCINOMA IN MICE INDUCED BY 4-NITROQUINOLINE 1-OXIDE: CARCINOMA ARISING FROM AREAS OF ADENOMA.
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Adenoma; Animals; Carcinogens; Carcinoma; Lung Neoplasms; | 1964 |
INDUCTION OF PULMONARY AND UTERINE TUMORS IN RATS BY SUBCUTANEOUS INJECTIONS OF 4-NITROQUINOLINE 1-OXIDE.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Female; Humans; Injections, Subcutaneous; Lung Neopl | 1964 |
FURTHER STUDIES ON THE HISTOGENESIS OF PULMONARY TUMORS IN MICE INDUCED BY 4-NITROQUINOLINE 1-OXIDE.
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Adenoma; Carcinogens; Lung Neoplasms; Mice; Neoplasms; Neo | 1964 |
[FORMATION OF EXPERIMENTAL BONE NEOPLASMS BY A CHEMICAL SUBSTANCE, 4-NITROQUINOLINE-N-OXIDE].
Topics: 4-Nitroquinoline-1-oxide; Animals; Bone Neoplasms; Femur; Neoplasms, Experimental; Pathology; Quinol | 1964 |
INDUCTION OF PULMONARY TUMOR AND LEUKEMIA BY A SINGLE INJECTION OF 4-NITROQUINOLINE 1-OXIDE TO NEWBORN AND INFANT MICE.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Leukemia; Leukemia, Experimental; Lung Neoplasms; Ne | 1964 |
PULMONARY CARCINOMA INDUCED BY A SINGLE SUBCUTANEOUS INJECTION OF 4-NITROQUINOLINE 1-OXIDE INTO NEW-BORN MICE.
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Animals, Newborn; Carcinogens; Injections, Subcut | 1965 |
Histological and histochemical study of the early lesions of mouse skin after a single application of 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Mice; Neoplasms, Experimental; Oxides; Quinolines; S | 1959 |
The effect of 4-nitroquinoline N-oxide on transplanted tumors.
Topics: 4-Nitroquinoline-1-oxide; Animals; Neoplasm Transplantation; Neoplasms, Experimental; Oxides; Quinol | 1960 |
Preliminary note on adenocarcinoma of the lung in mice induced with 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Carcinogens; Lung Neoplasms; Mice; Neoplasms, Exp | 1961 |
Chemopreventive efficacy of all-trans-retinoic acid in biodegradable microspheres against epithelial cancers: results in a 4-nitroquinoline 1-oxide-induced oral carcinogenesis model.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Transformat | 2006 |
Preservation of gastric gland character in transplantable gastric adenocarcinoma (SG2B) of rats.
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Animals, Newborn; Female; gamma-Glutamyltransfera | 1981 |
The effect of iron deficiency on experimental oral carcinogenesis in the rat.
Topics: 4-Nitroquinoline-1-oxide; Anemia, Hypochromic; Animals; Body Weight; Carcinoma, Squamous Cell; Diet; | 1983 |
Focal acantholytic dyskeratosis in experimental oral carcinogenesis in rats.
Topics: 4-Nitroquinoline-1-oxide; Acantholysis; Animals; Keratosis; Leukoplakia, Oral; Mouth Diseases; Mouth | 1983 |
Isolation and characterization of mitomycin-C-sensitive mouse lymphoma cell mutants.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cross-Linking Reagents; DNA Repair; Genetic Complementation Test; | 1983 |
Lethal and mutagenic effects of radiation and chemicals on cultured fish cells derived from the erythrophoroma of goldfish (Carassius auratus).
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cell Survival; Cyprinidae; Drug Resistance; Gamma Rays | 1983 |
Carcinogenesis in relation to the stem-cell-mutation hypothesis.
Topics: 4-Nitroquinoline-1-oxide; Aging; Animals; Cell Differentiation; Fetus; Humans; Mutation; Neoplasms; | 1983 |
4 Nitroquinoline 1-oxide-induced carcinogenesis in the rat palate.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Papillary; Disease Models, Animal; Neoplasms, Experime | 1983 |
Experimental induction of oral squamous cell carcinomas in mice with 4-nitroquinolone-1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Male; Mice; Mice, Inbred CBA; Mouth Muc | 1984 |
Timing of chemically induced neoplasia in mice revealed by the antineoplastic action of caffeine.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; DNA Repair; Ethylnitrosourea; Female; Hydroxamic Acids; | 1980 |
Mutation induction in a mouse lymphoma cell mutant sensitive to 4-nitroquinoline 1-oxide and ultraviolet radiation.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; Cell Line; Dose-Response Relationship, Drug; Dose-Respo | 1980 |
[Induction of squamous cell carcinoma of the oral cavity by administration of 4-nitroquinoline 1-oxide in the drinking water (author's transl)].
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Male; Mouth Neoplasms; Neoplasms, Exper | 1981 |
[Antitumor activities of bamboo leaf extracts (BLE) and its lignin (BLL)].
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents, Phytogenic; Benzopyrenes; Body Weight; Fem | 1981 |
Induction of squamous cell carcinoma in the oral cavity of rats by oral administration of 4-nitroquinoline-1-oxide (4NQO) in drinking water. A preliminary report.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Male; Mouth Neoplasms; Neoplasms, Exper | 1981 |
Multistep origin of tumor-forming ability in Chinese hamster embryo fibroblast cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Cricetulu | 1982 |
[Experimental lung cancer in rabbits, mice and rats induced by chemical carcinogens (author's transl)].
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Benzopyrenes; Carcinoma; Carcinoma, Squamous Cell | 1981 |
Experimental induction of irreversible precancerous changes in the palatal epithelium of the rat.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female | 1982 |
Diminution of chemically induced lung neoplasia in mice by phenobarbital pre-treatment.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Lung Neoplasms; Mice; Mice, Inb | 1982 |
Rapid induction of more malignant tumors by various genotoxic carcinogens in transgenic mice harboring a human prototype c-Ha-ras gene than in control non-transgenic mice.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogenicity Tests; Carcinogens; Cocarcinogenesis; Cyclophosph | 1996 |
Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination.
Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Body Weight; Carcinogens; Carcinoma, Squ | 1997 |
1,4-phenylenebis(methylene)selenocyanate exerts exceptional chemopreventive activity in rat tongue carcinogenesis.
Topics: 4-Nitroquinoline-1-oxide; Animals; Anticarcinogenic Agents; Biomarkers; Carcinogens; Carcinoma, Squa | 1997 |
Immortalization of mutant p53-transfected human fibroblasts by treatment with either 4-nitroquinoline 1-oxide or X-rays.
Topics: 4-Nitroquinoline-1-oxide; Animals; Blotting, Southern; Blotting, Western; Cell Line, Transformed; Ce | 1997 |
Cancer chemopreventive activity of euglobal-G1 from leaves of Eucalyptus grandis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antivi | 2000 |
Overexpression of JunB in undifferentiated malignant rat oral keratinocytes enhances the malignant phenotype in vitro without altering cellular differentiation.
Topics: 3T3 Cells; 4-Nitroquinoline-1-oxide; Animals; Bacterial Proteins; Blotting, Northern; Blotting, West | 2001 |
Transformation of BHK 21/13 cells by chemical carcinogens and mutagens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azacitidine; Benzopyrenes; Carcinogens; Cell Line; Cell Transform | 1975 |
On the significance of sex hormones in producing experimental prostate tumor in the rat.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Male; Methylcholanthrene; Neoplasm Meta | 1977 |
Histochemical and ultrastructural study of lactic dehydrogenase in chemically induced lung cancer.
Topics: 4-Nitroquinoline-1-oxide; Animals; Animals, Newborn; Embryo, Mammalian; Female; Histocytochemistry; | 1978 |
Effect of oil-attached BCG cell-wall skeleton and thymectomy on the incidence of lung cancer and amyloidosis induced by chemical carcinogens in rabbits.
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Amyloidosis; Animals; BCG Vaccine; Carcinoma, Squamous Cel | 1978 |
Carcinogenicity of 4-nitrosoquinoline 1-oxide and its possible role in carcinogenesis by 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; DNA, Bacterial; Escherichia coli; Female; Fibrosarcoma; Mice; Mut | 1978 |
Effect of different levels of dietary zinc on development of chemically induced oral cancer in rats.
Topics: 4-Nitroquinoline-1-oxide; Animals; Female; Mouth Neoplasms; Neoplasms, Experimental; Rats; Zinc | 1979 |
Isolation of a mammalian cell mutant sensitive to 4-nitroquinoline-1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cell Survival; Cells, Cultured; DNA Repair; DNA, Neopl | 1979 |
Influence of zinc on onset and progression of oral carcinogenesis in rats.
Topics: 4-Nitroquinoline-1-oxide; Animals; Copper; Female; Male; Mouth Mucosa; Mouth Neoplasms; Neoplasms, E | 1979 |
Carcinogenesis in tissue culture 24: tumorigenicity and aggregate-forming capacity of mammalian cells in culture.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Hepatocellular; Cell Aggregation; Cell Nucleolus; Cell | 1975 |
Suggestive evidence for relationship between sensitivity and repair capability in rat ascites hepatoma cells treated with the antitumor agent, 1-(gamma-chloropropyl)-2-chloromethylpiperidine hydrobromide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Hepatocellular; Cell Line; DNA Repair; DNA, Bacterial; | 1977 |
Similarity of the mechanism of chemical carcinogen-initiated teratogenesis and carcinogenesis in mice.
Topics: 4-Nitroquinoline-1-oxide; Abnormalities, Drug-Induced; Animals; Caffeine; Carcinogens; Congenital Ab | 1977 |
Neoplastic transformation of human diploid fibroblast cells by chemical carcinogens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Cell | 1978 |
Alterations in the lipid content of rat palatal epithelium during carcinogenesis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma in Situ; Carcinoma, S | 1975 |
Experimental production of osteogenic sarcoma of the mandible in rabbits with 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Chondrosarcoma; Female; Fibrosarcoma; Liver Neoplasms; Lung Neopl | 1975 |
Effects in rats of sodium chloride on experimental gastric cancers induced by N-methyl-N-nitro-N-nitrosoguanidine or 4-nitroquinoline-1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Carcinoma, Squamous Cell; Drug Synergism; Gastric | 1975 |
Carcinogenicity in mice of some fatty acid methyl esters. 2. Peroral and subcutaneous application.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinoge | 1975 |
Interval effect of beta-irradiation and subsequent 4-nitroquinoline 1-oxide painting on skin tumor induction in mice.
Topics: 4-Nitroquinoline-1-oxide; Administration, Topical; Animals; Female; Mice; Mice, Inbred ICR; Neoplasm | 1975 |
Differences in DNA-binding proteins isolate from normal and transformed human cells.
Topics: 4-Nitroquinoline-1-oxide; Cell Division; Cell Line; Cell Transformation, Neoplastic; Contact Inhibit | 1976 |
Diminution of tumorigenesis initiated by 4-nitroquinoline-1-oxide by post-treatment with caffeine in mice.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; DNA Repair; Female; Lung Neoplasms; Male; Mice; Mice, I | 1976 |
Experimental oral cancer in rats with xerostomia.
Topics: 4-Nitroquinoline-1-oxide; Animals; Chemical Phenomena; Chemistry, Physical; Lipids; Mucus; Neoplasms | 1976 |
[Study of experimental skin carcinogenesis (author's transl)].
Topics: 4-Nitroquinoline-1-oxide; Animals; Anthracenes; Female; Male; Methylcholanthrene; Mice; Neoplasms, E | 1976 |
Transplantation of chemically induced gastric cancer in Wistar rats.
Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Animals, Newborn; Lung Neoplasms; Male; Methylnit | 1976 |
Electron microscopic studies of placental and uterine tumors induced in rats.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Chori | 1976 |
In vitro transformation of hamster chondrocytes by 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cartilage; Cell Transformation, Neoplastic; Cells, Cultured; Cric | 1976 |
Lack of promoting ability of snuff in rats initiated with 4-nitroquinoline-N-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Male; Neoplasms, Experimental; Plants, Toxic; Rats; Rats, Inbred | 1991 |
Quantification of oral epithelial hyperplasia in rats after topical application of the carcinogen 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Epithelium; Hyperplasia; Mouth Mucosa; Neoplasms, Experimental; P | 1990 |
Experimental tongue carcinoma of rats induced by oral administration of 4-nitroquinoline 1-oxide (4NQO) in drinking water.
Topics: 4-Nitroquinoline-1-oxide; Administration, Oral; Animals; Carcinoma; Carcinoma in Situ; Male; Neoplas | 1985 |