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4-nitroquinoline-1-oxide and Esophageal Squamous Cell Carcinoma

4-nitroquinoline-1-oxide has been researched along with Esophageal Squamous Cell Carcinoma in 11 studies

4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.

Esophageal Squamous Cell Carcinoma: A carcinoma that originates usually from cells on the surface of the middle and lower third of the ESOPHAGUS. Tumor cells exhibit typical squamous morphology and form large polypoid lesions. Mutations in RNF6, LZTS1, TGFBR2, DEC1, and WWOX1 genes are associated with this cancer.

Research Excerpts

ExcerptRelevanceReference
" We used the 4-nitroquinoline-1-oxide (4-NQO) murine model of oral carcinogenesis and the Meadows-Cook model of alcohol abuse to assess changes in the expression of molecular markers during the initial stages of ESCC."7.81Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model. ( Gudas, LJ; Osei-Sarfo, K; Scognamiglio, T; Tang, XH; Urvalek, AM, 2015)
" We used the 4-nitroquinoline-1-oxide (4-NQO) murine model of oral carcinogenesis and the Meadows-Cook model of alcohol abuse to assess changes in the expression of molecular markers during the initial stages of ESCC."3.81Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model. ( Gudas, LJ; Osei-Sarfo, K; Scognamiglio, T; Tang, XH; Urvalek, AM, 2015)
"Esophageal cancer occurs as either squamous cell carcinoma (ESCC) or adenocarcinoma."1.48Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence. ( Cimperman, KA; Ehrman, LA; Guasch, G; Haas, SR; Komurov, K; Lane, A; Matrka, MC; Waclaw, RR; Wells, SI; Wikenheiser-Brokamp, KA, 2018)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (63.64)24.3611
2020's4 (36.36)2.80

Authors

AuthorsStudies
He, Y1
Rivera, J1
Diossy, M1
Duan, H1
Bowman-Colin, C1
Reed, R1
Jennings, R1
Novak, J1
Tran, SV1
Cohen, EF1
Szuts, D1
Giobbie-Hurder, A1
Bronson, RT1
Bass, AJ1
Signoretti, S1
Szallasi, Z1
Livingston, DM1
Pathania, S1
Luo, Y1
Du, L1
Yao, Z1
Liu, F1
Li, K1
Li, F1
Zhu, J1
Coppes, RP1
Zhang, D1
Pan, Y1
Gao, S1
Zhang, H1
Aziz, Z1
Washington, MK1
Jacobse, J1
Choksi, Y1
Han, L1
Gao, QL1
Zhou, XM1
Shi, C1
Chen, GY1
Song, YP1
Yao, YJ1
Zhao, YM1
Wen, XY1
Liu, SL1
Qi, YM1
Gao, YF1
Matrka, MC1
Cimperman, KA1
Haas, SR1
Guasch, G1
Ehrman, LA1
Waclaw, RR1
Komurov, K1
Lane, A1
Wikenheiser-Brokamp, KA1
Wells, SI1
Zhao, L1
Ma, M1
Wu, H1
Zhang, C1
Dai, S1
Dong, P1
Huo, B1
Shan, B1
Chen, MF1
Kuan, FC1
Yen, TC1
Lu, MS1
Lin, PY1
Chung, YH1
Chen, WC1
Lee, KD1
Wang, S2
Du, Z1
Luo, J1
Wang, X1
Li, H1
Liu, Y1
Zhang, Y1
Ma, J1
Xiao, W1
Wang, Y1
Zhong, X1
Osei-Sarfo, K1
Urvalek, AM1
Tang, XH1
Scognamiglio, T1
Gudas, LJ1
Wang, L1
Cao, NN1
Man, HW1
Li, PF1
Shan, BE1
Chen, CH1
Lu, HI1
Wang, YM1
Chen, YH1
Lo, CM1
Huang, WT1
Li, SH1

Other Studies

11 other studies available for 4-nitroquinoline-1-oxide and Esophageal Squamous Cell Carcinoma

ArticleYear
    Proceedings of the National Academy of Sciences of the United States of America, 2021, 10-12, Volume: 118, Issue:41

    Topics: 4-Nitroquinoline-1-oxide; Animals; BRCA1 Protein; Cell Line, Tumor; Cell Transformation, Neoplastic;

2021
Generation and Application of Inducible Chimeric RNA
    Cells, 2022, 01-14, Volume: 11, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Body Weight; Carcinogens; Disease Models, Animal; Esophageal Neop

2022
A method for scoring 4-nitroquinoline 1-oxide-induced murine esophageal squamous neoplasia.
    Veterinary pathology, 2023, Volume: 60, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Carcinoma; Esophageal Neoplasms; Esophageal Squamous

2023
Characterization of CD103
    Cancer immunology, immunotherapy : CII, 2020, Volume: 69, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Animals; Antibodies, Monoclonal; Antigens, CD; Biomarkers, Tu

2020
Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence.
    PLoS genetics, 2018, Volume: 14, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; DNA-Binding Proteins; Epithelium; Esoph

2018
p-Hydroxylcinnamaldehyde slows the progression of 4NQO-induced oesophageal tumourigenesis via the RhoA-MAPK signaling pathway.
    Molecular carcinogenesis, 2018, Volume: 57, Issue:10

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogenesis; Cinnamates; Disease Progression; Esophageal Neopl

2018
IL-6-stimulated CD11b+ CD14+ HLA-DR- myeloid-derived suppressor cells, are associated with progression and poor prognosis in squamous cell carcinoma of the esophagus.
    Oncotarget, 2014, Sep-30, Volume: 5, Issue:18

    Topics: 4-Nitroquinoline-1-oxide; Animals; Arginase; Carcinoma, Squamous Cell; Case-Control Studies; CD11b A

2014
Inhibition of heat shock protein 90 suppresses squamous carcinogenic progression in a mouse model of esophageal cancer.
    Journal of cancer research and clinical oncology, 2015, Volume: 141, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Carcinoma, Squamous Cell; Cell Proliferation; Cell T

2015
Initiation of esophageal squamous cell carcinoma (ESCC) in a murine 4-nitroquinoline-1-oxide and alcohol carcinogenesis model.
    Oncotarget, 2015, Mar-20, Volume: 6, Issue:8

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogenesis; Carcinogens; Carcinoma, Squamous Cell; Cell Proli

2015
Roles of coinhibitory molecules B7-H3 and B7-H4 in esophageal squamous cell carcinoma.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Animals; B7 Antigens; Carcinoma, Squamous Cell; Cell Line, Tu

2016
Areca nut is associated with younger age of diagnosis, poor chemoradiotherapy response, and shorter overall survival in esophageal squamous cell carcinoma.
    PloS one, 2017, Volume: 12, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Aged, 80 and over; Animals; Antineoplastic Agents; Areca; Are

2017