4-nitroquinoline-1-oxide has been researched along with Carcinoma, Hepatocellular in 4 studies
4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.
Carcinoma, Hepatocellular: A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among eight ascites hepatoma cell lines, AH-13 was extremely sensitive both to in vivo antitumor and to in vitro lethal action of the agent, whereas AH-44 was resistant in both cases." | 1.26 | Suggestive evidence for relationship between sensitivity and repair capability in rat ascites hepatoma cells treated with the antitumor agent, 1-(gamma-chloropropyl)-2-chloromethylpiperidine hydrobromide. ( Fukuda, S; Hatano, M; Koshiura, R; Miyamoto, K, 1977) |
| "among rat liver cells untreated, hepatoma cells produced by back-transplantation of rat liver cells after the treatment with a chemical carcinogen in tissue culture, and the hepatoma cells passaged serially through rats." | 1.25 | Carcinogenesis in tissue culture 24: tumorigenicity and aggregate-forming capacity of mammalian cells in culture. ( Akatsuka, T; Katsuta, H; Takaoka, T, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Valentin-Severin, I | 1 |
| Le Hegarat, L | 1 |
| Lhuguenot, JC | 1 |
| Le Bon, AM | 1 |
| Chagnon, MC | 1 |
| Morrow, CS | 1 |
| Smitherman, PK | 1 |
| Townsend, AJ | 1 |
| Takaoka, T | 1 |
| Katsuta, H | 1 |
| Akatsuka, T | 1 |
| Fukuda, S | 1 |
| Koshiura, R | 1 |
| Miyamoto, K | 1 |
| Hatano, M | 1 |
4 other studies available for 4-nitroquinoline-1-oxide and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Benzo(a)pyrene; Carcinoma, Hepatocellular; Comet As | 2003 |
Role of multidrug-resistance protein 2 in glutathione S-transferase P1-1-mediated resistance to 4-nitroquinoline 1-oxide toxicities in HepG2 cells.
Topics: 4-Nitroquinoline-1-oxide; ATP Binding Cassette Transporter, Subfamily B; Carcinogens; Carcinoma, Hep | 2000 |
Carcinogenesis in tissue culture 24: tumorigenicity and aggregate-forming capacity of mammalian cells in culture.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Hepatocellular; Cell Aggregation; Cell Nucleolus; Cell | 1975 |
Suggestive evidence for relationship between sensitivity and repair capability in rat ascites hepatoma cells treated with the antitumor agent, 1-(gamma-chloropropyl)-2-chloromethylpiperidine hydrobromide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Hepatocellular; Cell Line; DNA Repair; DNA, Bacterial; | 1977 |