4-nitroquinoline-1-oxide has been researched along with Cancer of Skin in 30 studies
4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lymphoblastoid cell lines established from three unrelated kindreds with familial melanoma (FM) were cytogenetically analyzed for spontaneous and 4-nitroquinoline-1-oxide (4NQO)-induced chromosome aberrations." | 3.67 | Spontaneous and 4-nitroquinoline 1-oxide-induced G2 chromosome aberrations in lymphoblasts from familial melanoma patients. ( Hayward, NK; Lu, GH; Stanley, WS, 1989) |
| " Dose-response relationships were evident in both studies when the data were categorized by quartiles of breaks/cell in the controls, with highest risk estimates being in the top quartile of induced breaks." | 1.29 | Mutagen sensitivity exhibits a dose-response relationship in case-control studies. ( Hsu, TC; Spitz, MR; Wu, X, 1996) |
| "The papillomas are heterogeneous in their potential for progression to carcinomas, a property apparently induced at the time of initiation." | 1.28 | Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin. ( Hennings, H, 1991) |
| "The dysplastic nevus syndrome (DNS) is a preneoplastic melanocyte abnormality which occurs in families affected by hereditary cutaneous malignant melanoma (HCMM)." | 1.27 | Abnormal responses to the carcinogen 4-nitroquinoline 1-oxide of cultured fibroblasts from patients with dysplastic nevus syndrome and hereditary cutaneous malignant melanoma. ( Adams, D; Greene, MH; Paterson, MC; Smith, PJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (63.33) | 18.7374 |
| 1990's | 6 (20.00) | 18.2507 |
| 2000's | 3 (10.00) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, LE | 2 |
| Li, C | 1 |
| Xiong, P | 2 |
| Gershenwald, JE | 1 |
| Prieto, VG | 1 |
| Duvic, M | 2 |
| Lee, JE | 1 |
| Grimm, EA | 1 |
| Hsu, TC | 3 |
| Wei, Q | 2 |
| Zhong, R | 1 |
| Bao, R | 1 |
| Faber, PW | 1 |
| Bindokas, VP | 1 |
| Bechill, J | 1 |
| Lingen, MW | 1 |
| Spiotto, MT | 1 |
| TAKAYAMA, S | 3 |
| OOTA, K | 1 |
| SEARLE, CE | 2 |
| WOODHOUSE, DL | 2 |
| HAYASHI, Y | 1 |
| Strom, SS | 1 |
| Clayman, GL | 1 |
| Weber, RS | 1 |
| Lippman, SM | 1 |
| Goldberg, LH | 1 |
| Smith, PJ | 1 |
| Greene, MH | 3 |
| Adams, D | 1 |
| Paterson, MC | 1 |
| Howell, JN | 2 |
| Corner, RC | 1 |
| Maher, VM | 2 |
| McCormick, JJ | 2 |
| Ito, N | 1 |
| Wu, X | 1 |
| Spitz, MR | 1 |
| Takasaki, M | 3 |
| Tokuda, H | 4 |
| Nishino, H | 4 |
| Konoshima, T | 3 |
| Etoh, H | 1 |
| Pal Singh, I | 1 |
| Komatsu, K | 1 |
| Takebe, H | 1 |
| Klaer, HW | 1 |
| Glavind, J | 1 |
| Arffmann, E | 1 |
| Ahlström, U | 1 |
| Mark, J | 1 |
| Hoshino, H | 1 |
| Tanooka, H | 1 |
| Yamaguchi, Z | 1 |
| Murakoshi, M | 1 |
| Satomi, Y | 1 |
| Takayasu, J | 1 |
| Hasegawa, T | 1 |
| Iwashima, A | 1 |
| Okuzumi, J | 1 |
| Okabe, H | 1 |
| Kitano, H | 1 |
| Miller, JA | 1 |
| Hennings, H | 2 |
| Shores, R | 1 |
| Balaschak, M | 1 |
| Yuspa, SH | 1 |
| Rhim, JS | 1 |
| Fujita, J | 1 |
| Arnstein, P | 1 |
| Aaronson, SA | 1 |
| Lu, GH | 1 |
| Hayward, NK | 1 |
| Stanley, WS | 1 |
| Sugimura, T | 1 |
| Chu, KC | 1 |
| Brown, CC | 1 |
| Tarone, RE | 1 |
| Tan, WY | 1 |
| Sato, K | 1 |
2 reviews available for 4-nitroquinoline-1-oxide and Cancer of Skin
| Article | Year |
|---|---|
In vivo carcinogenesis of 4-nitroquinoline 1-oxide and related compounds.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Esophageal Neoplasms; Intestinal Neoplasms; Liver Ne | 1981 |
[DNA repair and carcinogenesis (author's transl)].
Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Animals; Cell Survival; Child; Deoxyribodipyrimidine Ph | 1978 |
28 other studies available for 4-nitroquinoline-1-oxide and Cancer of Skin
| Article | Year |
|---|---|
4-nitroquinoline-1-oxide-induced mutagen sensitivity and risk of cutaneous melanoma: a case-control analysis.
Topics: 4-Nitroquinoline-1-oxide; Adult; Case-Control Studies; Dose-Response Relationship, Drug; Female; Hum | 2016 |
Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Breast Neoplasms; Carcinogens; | 2015 |
Effect of 4-nitroquinoline N-oxide painting on azo dye hepatocarcinogenesis in rats, with note on induction of skin fibrosarcoma.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azo Compounds; Carcinogens; Coloring Agents; Fibrosarcoma; Liver | 1961 |
Skin carcinogenesis with a single painting of 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogenesis; Carcinogens; Neoplasms, Experimental; Oxides; Pai | 1960 |
Correlative histochemical and autoradiographical studies on the mouse skin after the painting with tritium labeled 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Autoradiography; Carcinogens; Mice; Neoplasms, Experimental; Oxid | 1961 |
THE CARCINOGENICITY AND REACTIVITY TO TISSUE CONSTITUENTS OF 4-NITROQUINOLINE-N-OXIDE.
Topics: 4-Nitroquinoline-1-oxide; Animals; Benzopyrenes; Guinea Pigs; Liver; Metabolism; Mice; Neoplasms; Ne | 1963 |
4-NITROQUINOLINE N-OXIDE: AN INHIBITOR OF BENZPYRENE CARCINOGENESIS OF MOUSE SKIN.
Topics: 4-Nitroquinoline-1-oxide; Animals; Benzopyrenes; Carcinogenesis; Carcinogens; Mice; Neoplasms; Neopl | 1964 |
Histological and histochemical study of the early lesions of mouse skin after a single application of 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Mice; Neoplasms, Experimental; Oxides; Quinolines; S | 1959 |
4-Nitroquinoline-1-oxide-induced mutagen sensitivity and risk of nonmelanoma skin cancer: a case-control analysis.
Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Aged, 80 and over; Carcinoma, Basal Cell; Carcinoma, Squamous | 2007 |
Abnormal responses to the carcinogen 4-nitroquinoline 1-oxide of cultured fibroblasts from patients with dysplastic nevus syndrome and hereditary cutaneous malignant melanoma.
Topics: 4-Nitroquinoline-1-oxide; Cell Line; Cell Survival; Cells, Cultured; DNA Repair; DNA Replication; Fi | 1983 |
Fibroblasts from patients with hereditary cutaneous malignant melanoma are abnormally sensitive to the mutagenic effect of simulated sunlight and 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Adult; Cells, Cultured; Dose-Response Relationship, Radiation; Female; Fib | 1984 |
Mutagen sensitivity exhibits a dose-response relationship in case-control studies.
Topics: 4-Nitroquinoline-1-oxide; Antibiotics, Antineoplastic; Bleomycin; Case-Control Studies; Cell Culture | 1996 |
Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antineoplastic Agents, Phytogenic; Antiviral Agents; Carcinogens; | 1999 |
Cancer chemopreventive activity of euglobal-G1 from leaves of Eucalyptus grandis.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Antivi | 2000 |
Anti-tumor-promoting activity of lignans from the aerial part of Saussurea medusa.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Administration, To | 2000 |
Carcinogenicity in mice of some fatty acid methyl esters. 2. Peroral and subcutaneous application.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Carcinoge | 1975 |
Cytogenetic analysis of oral and cutaneous squamous cell carcinomas in the rat.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell | 1975 |
Interval effect of beta-irradiation and subsequent 4-nitroquinoline 1-oxide painting on skin tumor induction in mice.
Topics: 4-Nitroquinoline-1-oxide; Administration, Topical; Animals; Female; Mice; Mice, Inbred ICR; Neoplasm | 1975 |
[Study of experimental skin carcinogenesis (author's transl)].
Topics: 4-Nitroquinoline-1-oxide; Animals; Anthracenes; Female; Male; Methylcholanthrene; Mice; Neoplasms, E | 1976 |
Potent preventive action of alpha-carotene against carcinogenesis: spontaneous liver carcinogenesis and promoting stage of lung and skin carcinogenesis in mice are suppressed more effectively by alpha-carotene than by beta-carotene.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; beta Caro | 1992 |
4-Nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinoma, Squamous Cell; Humans; Mutagens; Skin Neoplasms | 1991 |
Malignant conversion, the first stage in progression, is distinct from phorbol ester promotion in mouse skin.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acetone; Animals; Carcinoma, Squamous Ce | 1991 |
Sensitivity of subpopulations of mouse skin papillomas to malignant conversion by urethane or 4-nitroquinoline N-oxide.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma; Cocarcinogenesis; Mi | 1990 |
Neoplastic conversion of human keratinocytes by adenovirus 12-SV40 virus and chemical carcinogens.
Topics: 4-Nitroquinoline-1-oxide; Adenoviruses, Human; Animals; Cell Line; Cell Transformation, Neoplastic; | 1986 |
Spontaneous and 4-nitroquinoline 1-oxide-induced G2 chromosome aberrations in lymphoblasts from familial melanoma patients.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Aberrations; Humans; Interphase; Lymphocytes; Melanoma; Neoplas | 1989 |
Historical background of studies on environmental chemical carcinogenesis in Japan and recent progress in toxicology of carcinogens.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Coal Tar; Diet; En | 1986 |
Differentiating among proposed mechanisms for tumor promotion in mouse skin with the use of the multievent model for cancer.
Topics: 4-Nitroquinoline-1-oxide; Acetone; Animals; Cell Transformation, Neoplastic; Mathematics; Mice; Mode | 1987 |
Relationship between sensitivity of cells from patients with hereditary cutaneous malignant melanoma to killing and mutations by 4-nitroquinoline 1-oxide and adduct formation.
Topics: 4-Nitroquinoline-1-oxide; Cell Line; Cell Survival; Dysplastic Nevus Syndrome; Humans; Male; Melanom | 1988 |