Compounds > 4-nitroquinoline-1-oxide
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4-nitroquinoline-1-oxide and Benign Neoplasms

4-nitroquinoline-1-oxide has been researched along with Benign Neoplasms in 28 studies

4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.

Research Excerpts

ExcerptRelevanceReference
"Post-treatment with caffeine greatly diminishes the yields by 4NQO of mutants in E."2.36A test for mutation theory of cancer: carcinogenesis by misrepair of DNA damaged by 4-nitroquinoline 1-oxide. ( Kondo, S, 1977)
"Moreover, chemical carcinogenesis can promote stressor-like effects with hormonal changes in the tissue microenvironment, which may be associated to tumor progression."1.48Stress hormones concentrations in the normal microenvironment predict risk for chemically induced cancer in rats. ( Bernabé, DG; Biasoli, ÉR; de Andrade, M; de Oliveira, SHP; Dos Santos, PSP; Ferreira, JZ; Lopes, FYK; Miyahara, GI; Soubhia, AMP; Sundefeld, MLMM; Valente, VB; Verza, FA, 2018)
"Head and neck squamous cell carcinoma (HNSCC) development is a multistage process includes the normal, dysplasia and squamous cell carcinoma (SCC) stages."1.43Modulation of IL-1β reprogrammes the tumor microenvironment to interrupt oral carcinogenesis. ( Cheng, B; Hong, Y; Hu, Q; Jia, L; Wang, J; Wu, J; Wu, T; Xia, J, 2016)
"Three in 10 patients with stomach cancer and 4 in 16 patients with other cancers were sensitive to induction of SCE by methyl methanesulfonate."1.27Novel responses of peripheral lymphocytes of cancer patients to chemical induction of sister chromatid exchanges. ( Horaguchi, K; Kikuchi, J; Nakada, T; Oikawa, A; Sugawara, R; Takahashi, K; Tohda, H; Wakui, A; Yamauchi, A, 1986)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199020 (71.43)18.7374
1990's2 (7.14)18.2507
2000's2 (7.14)29.6817
2010's4 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Viarisio, D1
Robitaille, A1
Müller-Decker, K1
Flechtenmacher, C1
Gissmann, L1
Tommasino, M1
Valente, VB1
Verza, FA1
Lopes, FYK1
Ferreira, JZ1
Dos Santos, PSP1
Sundefeld, MLMM1
Biasoli, ÉR1
Miyahara, GI1
Soubhia, AMP1
de Andrade, M1
de Oliveira, SHP1
Bernabé, DG1
Wu, X2
Zheng, YL1
Hsu, TC2
Wu, T1
Hong, Y1
Jia, L1
Wu, J1
Xia, J1
Wang, J1
Hu, Q1
Cheng, B1
Li, C1
Wang, LE1
Wei, Q1
Kaleeswaran, S1
Sriram, P1
Prabhu, D1
Mathuram, LN1
FUKUOKA, F2
SUGIMURA, T1
ONO, T1
OHASHI, M1
NISHIMURA, S1
SHIRASU, Y2
SEARLE, CE2
WOODHOUSE, DL2
MORI, K3
NISHIZUKA, Y1
NAKAKUKI, K1
SAKAKURA, T1
HISAMATSU, T1
OKAMOTO, K1
Kondo, S2
Watanabe, M1
Kuroki, T1
Tsonis, PA1
Eguchi, G1
Townsend, AJ1
Fields, WR1
Haynes, RL1
Doss, AJ1
Li, Y1
Doehmer, J1
Morrow, CS1
Gu, J1
Bondy, ML1
Sigurdson, A1
Spitz, MR1
Hadler, HI1
Cao, TM1
Takebe, H2
Namba, M1
Nishitani, K1
Kimoto, T1
Ikenaga, M1
Ishii, Y1
Tada, M1
Kakunaga, T1
Oikawa, A1
Horaguchi, K1
Sugawara, R1
Kikuchi, J1
Tohda, H1
Takahashi, K1
Wakui, A1
Yamauchi, A1
Nakada, T1

Reviews

5 reviews available for 4-nitroquinoline-1-oxide and Benign Neoplasms

ArticleYear
DNA repair phenotype and cancer susceptibility--a mini review.
    International journal of cancer, 2009, Mar-01, Volume: 124, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; DNA Adducts; DNA Repai

2009
[In Search of the mechanism of neoplastic cell transformation--the current confused state].
    Radioisotopes, 1983, Volume: 32, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA;

1983
In vitro carcinogenesis by 4-nitroquinoline 1-oxide and related compounds.
    Carcinogenesis; a comprehensive survey, 1981, Volume: 6

    Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; Carcinogens; Cell Cycle; Cell Transformation, Neoplasti

1981
[DNA repair and carcinogenesis (author's transl)].
    Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme, 1978, Volume: 23, Issue:6

    Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Animals; Cell Survival; Child; Deoxyribodipyrimidine Ph

1978
A test for mutation theory of cancer: carcinogenesis by misrepair of DNA damaged by 4-nitroquinoline 1-oxide.
    British journal of cancer, 1977, Volume: 35, Issue:5

    Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; Cell Transformation, Neoplastic; DNA; DNA Repair; DNA,

1977

Other Studies

23 other studies available for 4-nitroquinoline-1-oxide and Benign Neoplasms

ArticleYear
Cancer susceptibility of beta HPV49 E6 and E7 transgenic mice to 4-nitroquinoline 1-oxide treatment correlates with mutational signatures of tobacco exposure.
    Virology, 2019, Volume: 538

    Topics: 4-Nitroquinoline-1-oxide; Animals; Betapapillomavirus; Disease Susceptibility; Female; Humans; Mice;

2019
Stress hormones concentrations in the normal microenvironment predict risk for chemically induced cancer in rats.
    Psychoneuroendocrinology, 2018, Volume: 89

    Topics: 4-Nitroquinoline-1-oxide; Adrenocorticotropic Hormone; Animals; Biomarkers, Tumor; Brain-Derived Neu

2018
Mutagen sensitivity as measured by induced chromatid breakage as a marker of cancer risk.
    Methods in molecular biology (Clifton, N.J.), 2014, Volume: 1105

    Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Bleomycin; Cells, Cult

2014
Modulation of IL-1β reprogrammes the tumor microenvironment to interrupt oral carcinogenesis.
    Scientific reports, 2016, Feb-01, Volume: 6

    Topics: 4-Nitroquinoline-1-oxide; Administration, Oral; Animals; Carcinoma, Squamous Cell; Cell Line, Tumor;

2016
Anti- and pro-mutagenic effects of silymarin in the Ames bacterial reverse mutation assay.
    Phytotherapy research : PTR, 2009, Volume: 23, Issue:10

    Topics: 4-Nitroquinoline-1-oxide; Animals; Antimutagenic Agents; Antineoplastic Agents, Phytogenic; Antioxid

2009
Anti-cancer action of 6-carboxy-4-nitroquinoline 1-oxide.
    Gan, 1957, Volume: 48, Issue:3

    Topics: 4-Nitroquinoline-1-oxide; Antineoplastic Agents; Humans; Neoplasms; Oxides

1957
Effect of 4-nitroquinoline N-oxide on the metabolism of cancer cells in vitro.
    Gan, 1959, Volume: 50, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Carcinogens; Humans; In Vitro Techniques; Neoplasms; Nitrites; Oxides; Qui

1959
A carcinogenic experiment with 4-nitroquinoline 1-oxide in guinea pig.
    Gan, 1962, Volume: 53

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Guinea Pigs; Neoplasms; Neoplasms, Experimental; Oxi

1962
THE CARCINOGENICITY AND REACTIVITY TO TISSUE CONSTITUENTS OF 4-NITROQUINOLINE-N-OXIDE.
    Acta - Unio Internationalis Contra Cancrum, 1963, Volume: 19

    Topics: 4-Nitroquinoline-1-oxide; Animals; Benzopyrenes; Guinea Pigs; Liver; Metabolism; Mice; Neoplasms; Ne

1963
4-NITROQUINOLINE N-OXIDE: AN INHIBITOR OF BENZPYRENE CARCINOGENESIS OF MOUSE SKIN.
    Cancer research, 1964, Volume: 24

    Topics: 4-Nitroquinoline-1-oxide; Animals; Benzopyrenes; Carcinogenesis; Carcinogens; Mice; Neoplasms; Neopl

1964
INDUCTION OF PULMONARY AND UTERINE TUMORS IN RATS BY SUBCUTANEOUS INJECTIONS OF 4-NITROQUINOLINE 1-OXIDE.
    Gan, 1964, Volume: 55

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Female; Humans; Injections, Subcutaneous; Lung Neopl

1964
FURTHER STUDIES ON THE HISTOGENESIS OF PULMONARY TUMORS IN MICE INDUCED BY 4-NITROQUINOLINE 1-OXIDE.
    Gan, 1964, Volume: 55

    Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Adenoma; Carcinogens; Lung Neoplasms; Mice; Neoplasms; Neo

1964
COMPARATIVE CARCINOGENICITY OF 4-NITROQUINOLINE 1-OXIDE AND 4-HYDROXYAMINOQUINOLINE 1-OXIDE IN 3 STRAINS OF MICE.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1965, Volume: 118

    Topics: 4-Hydroxyaminoquinoline-1-oxide; 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Leukemia; Leukemia,

1965
INDUCTION OF PULMONARY TUMOR AND LEUKEMIA BY A SINGLE INJECTION OF 4-NITROQUINOLINE 1-OXIDE TO NEWBORN AND INFANT MICE.
    Gan, 1964, Volume: 55

    Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Leukemia; Leukemia, Experimental; Lung Neoplasms; Ne

1964
PULMONARY CARCINOMA INDUCED BY A SINGLE SUBCUTANEOUS INJECTION OF 4-NITROQUINOLINE 1-OXIDE INTO NEW-BORN MICE.
    Gan, 1965, Volume: 56

    Topics: 4-Nitroquinoline-1-oxide; Adenocarcinoma; Animals; Animals, Newborn; Carcinogens; Injections, Subcut

1965
Carcinogenesis in relation to the stem-cell-mutation hypothesis.
    Differentiation; research in biological diversity, 1983, Volume: 24, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Aging; Animals; Cell Differentiation; Fetus; Humans; Mutation; Neoplasms;

1983
Carcinogens on regeneration. Effects of N-methyl-N'-nitro-N-nitrosoguanidine and 4-nitroquinoline-1-oxide on limb regeneration in adult newts.
    Differentiation; research in biological diversity, 1981, Volume: 20, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Abnormalities, Drug-Induced; Animals; Bone and Bones; Forelimb; Methylnitr

1981
Chemoprotective functions of glutathione S-transferases in cell lines induced to express specific isozymes by stable transfection.
    Chemico-biological interactions, 1998, Apr-24, Volume: 111-112

    Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Alkylation; Animals; C

1998
Three measures of mutagen sensitivity in a cancer-free population.
    Cancer genetics and cytogenetics, 1999, Volume: 110, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide; Adult; Aged; Bleomycin

1999
Vitamin K and chemical carcinogenesis.
    Lancet (London, England), 1978, Feb-18, Volume: 1, Issue:8060

    Topics: 4-Nitroquinoline-1-oxide; Animals; Mitochondria, Liver; Neoplasms; Oxidative Phosphorylation; Rats;

1978
Carcinogenesis in tissue culture. 28. Comparison of various effects of a chemical carcinogen, 4-nitroquinoline I-oxide, on normal human cells and on normal mouse cells in culture.
    The Japanese journal of experimental medicine, 1977, Volume: 47, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured;

1977
Excision-repair of 4-nitroquinolin-1-oxide damage responsible for killing, mutation, and cancer.
    Basic life sciences, 1975, Volume: 5B

    Topics: 4-Nitroquinoline-1-oxide; Cell Line; Cell Survival; DNA Repair; DNA, Bacterial; Escherichia coli; Ki

1975
Novel responses of peripheral lymphocytes of cancer patients to chemical induction of sister chromatid exchanges.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: 4-Nitroquinoline-1-oxide; Aged; Carbolines; Colonic Neoplasms; Female; Humans; Lung Neoplasms; Lymph

1986