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4-nitroquinoline-1-oxide and Alzheimer Disease

4-nitroquinoline-1-oxide has been researched along with Alzheimer Disease in 2 studies

4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.

Alzheimer Disease: A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)

Research Excerpts

ExcerptRelevanceReference
"Validity of NQ2A-12 related to Alzheimer's disease was shown with an enhanced expression of Pin1 in a mouse brain tissue by injecting the NQ2A-12 extract."1.46A 4-Nitroquinoleneoxide-Induced Pleurotus eryngii Mutant Variety Increases Pin1 Expression in Rat Brain. ( Hwang, CH; Jeong, Y; Jung, M; Kim, MJ, 2017)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jeong, Y1
Jung, M1
Kim, MJ1
Hwang, CH1
Morimoto, K1
Miura, K1
Kaneko, T1
Iijima, K1
Sato, M1
Koizumi, A1

Other Studies

2 other studies available for 4-nitroquinoline-1-oxide and Alzheimer Disease

ArticleYear
A 4-Nitroquinoleneoxide-Induced Pleurotus eryngii Mutant Variety Increases Pin1 Expression in Rat Brain.
    Journal of medicinal food, 2017, Volume: 20, Issue:1

    Topics: 4-Nitroquinoline-1-oxide; Alzheimer Disease; Animals; Brain; Cytoplasmic Dyneins; Hep G2 Cells; Huma

2017
Human health situation and chromosome alterations: sister chromatid exchange frequency in lymphocytes from passive smokers and patients with hereditary diseases.
    Basic life sciences, 1984, Volume: 29 Pt B

    Topics: 4-Nitroquinoline-1-oxide; Adolescent; Adult; Alzheimer Disease; Anemia, Aplastic; Cell Cycle; Cells,

1984