4-nitroquinoline-1-oxide has been researched along with Abnormalities, Autosome in 64 studies
4-nitroquinoline N-oxide : A quinoline N-oxide carrying a nitro substituent at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lymphoblastoid cell lines established from three unrelated kindreds with familial melanoma (FM) were cytogenetically analyzed for spontaneous and 4-nitroquinoline-1-oxide (4NQO)-induced chromosome aberrations." | 3.67 | Spontaneous and 4-nitroquinoline 1-oxide-induced G2 chromosome aberrations in lymphoblasts from familial melanoma patients. ( Hayward, NK; Lu, GH; Stanley, WS, 1989) |
| " This study was designed to assess the shape of the dose-response curve at low concentrations of 4NQO in three human lymphoblastoid cell lines, MCL-5, AHH-1 and TK6 as well as the mouse lymphoma L5178Y cell line in vitro." | 1.43 | The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency. ( Brüsehafer, K; Doak, SH; Doherty, AT; Jenkins, GJ; Johnson, GE; Manshian, BB; Zaïr, ZM, 2016) |
| "Werner's syndrome (WS) and Bloom's syndrome (BS) are rare autosomal genetic diseases that predispose to cancer and are associated with genomic instability." | 1.31 | Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients. ( Furuichi, Y; Goto, M; Hayashi, M; Honma, M; Sakamoto, H; Satoh, T; Sofuni, T; Sugimoto, M; Tadokoro, S; Tanabe, H, 2002) |
| "Chromosomal aberrations were also synergistically increased in WRN(-/-)/BLM(-/-) cells when irradiated with UV light in late S to G(2) phases." | 1.31 | Werner and Bloom helicases are involved in DNA repair in a complementary fashion. ( Fujita, K; Furuichi, Y; Imamura, O; Itoh, C; Matsumoto, T; Takeda, S, 2002) |
| "Enhancement of chromosome aberrations induced by MMC was observed when CHO K1 cells were treated with Cd2+ during the G1 phase." | 1.29 | Inorganic cadmium increases the frequency of chemically induced chromosome aberrations in cultured mammalian cells. ( Miyahara, T; Sasaki, YF; Yamada, H, 1993) |
| "Different chromosomal aberrations were detectable directly in the pulsed field gel when growing yeast cells were incubated with a genotoxin for 6 h at 26 degrees C followed by treatment with the genotoxin for another twelve days at 4 degrees C." | 1.29 | Monitoring of induced chromosomal aberrations in S. cerevisiae in agarose gels by pulsed field gel electrophoresis. ( Fahrig, R; Steinkamp-Zucht, A, 1995) |
| "The frequencies of chromosomal aberrations induced by MMC and ENNG were correspondingly decreased at these pH values." | 1.28 | Effect of pH on the activity and stability of clastogens in the in vitro chromosomal aberration test with Chinese hamster ovary K1 cells. ( Fukuda, I; Morita, T; Nagaki, T; Okumura, K, 1991) |
| "Cell survival, chromosomal aberrations and SCEs were used as biological end-points." | 1.28 | Cytogenetical characterisation of Chinese hamster 43-3B transferants with the amplified or non-amplified human DNA repair gene ERCC-1. ( Darroudi, F; Natarajan, AT; Westerveld, A, 1989) |
| "We have quantified chromosome aberrations (CA) and sister chromatid exchanges (SCE) in the marrow cells of mice that had been injected with quinoline, 8-hydroxyquinoline, or 4-nitroquinoline-1-oxide up to levels approaching lethal." | 1.28 | Genotoxic potency of three quinoline compounds evaluated in vivo in mouse marrow cells. ( McFee, AF, 1989) |
| " This new testing system appears to be a sensitive method of measuring the direct effects of toxic chemicals which yields results in a short term." | 1.27 | Toxic effects of chemicals on mouse post-blastocyst development--a trial to establish a testing system for embryotoxicity. ( Katayama, S; Matsumoto, N, 1985) |
| "The frequency of x-ray-induced chromosome aberrations in G0 human lymphocytes was greatly increased when cells were incubated with cytosine arabinoside (ara-C) after irradiation." | 1.26 | DNA repair and chromosome aberrations: the effect of cytosine arabinoside on the frequency of chromosome aberrations induced by radiation and chemicals. ( Preston, RJ, 1980) |
| "The dose-response for the induction of acentric chromosome fragments was determined in neuroblasts of the grasshopper embryo (Chortophaga viridifasciata De Geer, Orthoptera: Acrididae) exposed in vitro to four direct-acting chemical known to be mutagenic, clastogenic, and carcinogenic: 4-nitroquinoline-1-oxide (4NQO), N-methyl-N-nitro-N-nitrosoguanidine (MNNG), Adriamycin (ADM), and bleomycin (BLM)." | 1.26 | Neuroblast of the grasshopper embryo as a new mutagen test system. II. Chromosome breakage induced by in vitro exposure of embryos to the direct-acting mutagens 4NQO, MNNG, adriamycin, and bleomycin. ( Gaulden, ME; Liang, JC, 1982) |
| "The frequency of metaphase plates with chromosome aberrations and the frequency of breaks and exchanges per chromosome complement were estimated following exposure to the carcinogens 4-nitroquinoline-1-oxide (4NQO),N-acetoxy-2-acetyl-aminofluorene (N-acetoxy-2-AAF), and N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), and to the mutagen daunomycin." | 1.26 | Differential sensitivity of Xeroderma pigmentosum cells of different repair capacities towards the chromosome breaking action of carcinogens and mutagens. ( San, RH; Stich, HF; Stich, W, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (64.06) | 18.7374 |
| 1990's | 15 (23.44) | 18.2507 |
| 2000's | 4 (6.25) | 29.6817 |
| 2010's | 4 (6.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Guo, X | 1 |
| Pan, B | 1 |
| Seo, JE | 1 |
| Chen, Y | 1 |
| Yan, J | 1 |
| Mei, N | 1 |
| Chen, T | 1 |
| Abraham, SK | 1 |
| Khandelwal, N | 1 |
| Hintzsche, H | 1 |
| Stopper, H | 1 |
| Brüsehafer, K | 1 |
| Manshian, BB | 1 |
| Doherty, AT | 1 |
| Zaïr, ZM | 1 |
| Johnson, GE | 1 |
| Doak, SH | 1 |
| Jenkins, GJ | 1 |
| Stankowski, LF | 1 |
| Roberts, DJ | 1 |
| Chen, H | 1 |
| Lawlor, T | 1 |
| McKeon, M | 1 |
| Murli, H | 1 |
| Thakur, A | 1 |
| Xu, Y | 1 |
| Honma, M | 2 |
| Tadokoro, S | 1 |
| Sakamoto, H | 1 |
| Tanabe, H | 1 |
| Sugimoto, M | 1 |
| Furuichi, Y | 2 |
| Satoh, T | 1 |
| Sofuni, T | 1 |
| Goto, M | 1 |
| Hayashi, M | 1 |
| Nomura, T | 1 |
| Nakajima, H | 1 |
| Ryo, H | 1 |
| Li, LY | 1 |
| Fukudome, Y | 1 |
| Adachi, S | 1 |
| Gotoh, H | 1 |
| Tanaka, H | 1 |
| Vlcková, V | 1 |
| Dúhová, V | 1 |
| Svidová, S | 1 |
| Farkassová, A | 1 |
| Kamasová, S | 1 |
| Vlcek, D | 1 |
| Kogan, G | 1 |
| Rauko, P | 1 |
| Miadoková, E | 1 |
| Preston, RJ | 3 |
| Shvetsova, TP | 3 |
| Zasukhina, GD | 4 |
| Bektemirov, TA | 1 |
| Andronova, AV | 2 |
| Barkova, EP | 1 |
| Liang, JC | 1 |
| Gaulden, ME | 1 |
| Makedonov, GP | 3 |
| Kriuchkov, VP | 1 |
| Kramer-Ageev, EA | 1 |
| Whitehead, FW | 1 |
| San, RH | 2 |
| Stich, HF | 5 |
| Takahashi, EI | 1 |
| Tobari, I | 3 |
| Shiomi, T | 2 |
| Sato, K | 3 |
| Sharief, Y | 1 |
| Reich, CF | 1 |
| Bonar, RA | 1 |
| Khachapuridze, GG | 1 |
| Mikhel'son, VM | 1 |
| Zhestianikov, VD | 1 |
| Shiraishi, Y | 3 |
| Sandberg, AA | 3 |
| Ikenaga, M | 1 |
| Takebe, H | 1 |
| Gooch, PC | 1 |
| Miyaki, M | 2 |
| Akamatsu, N | 2 |
| Ono, T | 1 |
| Tonomura, A | 1 |
| Utsunomiya, J | 2 |
| Parshad, R | 1 |
| Gantt, R | 1 |
| Sanford, KK | 1 |
| Jones, GM | 1 |
| Tarone, RE | 1 |
| Witjes, M | 1 |
| Scholma, J | 1 |
| van Drunen, E | 1 |
| Roodenburg, JL | 1 |
| Mesander, G | 1 |
| Hagemeijer, A | 1 |
| Tomson, AM | 1 |
| Yamada, H | 2 |
| Miyahara, T | 2 |
| Sasaki, YF | 3 |
| Kozuka, H | 1 |
| Matsuhashi, T | 1 |
| Patel, V | 1 |
| Poulopoulos, AK | 1 |
| Levan, G | 1 |
| Game, SM | 1 |
| Eveson, JW | 1 |
| Prime, SS | 1 |
| Bai, L | 1 |
| Mihara, K | 1 |
| Kondo, Y | 1 |
| Namba, M | 2 |
| Steinkamp-Zucht, A | 1 |
| Fahrig, R | 1 |
| Schuler, M | 1 |
| Rupa, DS | 1 |
| Eastmond, DA | 1 |
| Imamura, O | 1 |
| Fujita, K | 1 |
| Itoh, C | 1 |
| Takeda, S | 1 |
| Matsumoto, T | 1 |
| Popescu, NC | 2 |
| Amsbaugh, SC | 1 |
| Dipaolo, JA | 2 |
| MacRae, WD | 1 |
| MacKinnon, EA | 1 |
| Turnbull, D | 1 |
| Stich, W | 1 |
| Weinstein, D | 1 |
| Katz, ML | 1 |
| Kazmer, S | 1 |
| Nishitani, K | 1 |
| Kimoto, T | 1 |
| Tsutsui, T | 1 |
| Umeda, M | 1 |
| Maizumi, H | 1 |
| Saito, M | 1 |
| Warren, PM | 1 |
| Ahlström, U | 1 |
| Mark, J | 1 |
| Nagao, M | 1 |
| Sugimura, T | 1 |
| Matter, BE | 1 |
| Deng, CZ | 1 |
| AbuBakar, S | 1 |
| Fons, MP | 1 |
| Boldogh, I | 1 |
| Hokanson, J | 1 |
| Au, WW | 1 |
| Albrecht, T | 1 |
| Wasserman, SS | 2 |
| Cohen, MM | 1 |
| Schwartz, S | 2 |
| Wolff, DJ | 1 |
| Needleman, BW | 1 |
| Lefrançois, D | 1 |
| Kokalj, N | 1 |
| Viegas-Péquignot, E | 1 |
| Montagnier, L | 1 |
| Dutrillaux, B | 1 |
| Morita, T | 1 |
| Nagaki, T | 1 |
| Fukuda, I | 1 |
| Okumura, K | 1 |
| McFee, AF | 2 |
| Tice, RR | 1 |
| Chekova, VV | 1 |
| Yakubovskaya, EL | 1 |
| Gebhart, E | 2 |
| Bauer, R | 1 |
| Raub, U | 1 |
| Schinzel, M | 1 |
| Ruprecht, KW | 1 |
| Jonas, JB | 1 |
| Darroudi, F | 2 |
| Natarajan, AT | 2 |
| Lohman, PH | 1 |
| Westerveld, A | 1 |
| Shimoi, K | 1 |
| Nakamura, Y | 1 |
| Noro, T | 1 |
| Tomita, I | 1 |
| Imanishi, H | 1 |
| Matsumoto, K | 1 |
| Shirasu, Y | 1 |
| Lu, GH | 1 |
| Hayward, NK | 1 |
| Stanley, WS | 1 |
| Katayama, S | 1 |
| Matsumoto, N | 1 |
| Sato, C | 1 |
| Tanaka, T | 1 |
| Kuniyasu, T | 1 |
| Shima, H | 1 |
| Sugie, S | 1 |
| Mori, H | 1 |
| Takahashi, M | 1 |
| Hirono, I | 1 |
| Dunn, BP | 1 |
| Takahashi, E | 2 |
| Tsuji, H | 1 |
| Tsuji, S | 1 |
| Kishi, K | 1 |
| Kysela, D | 1 |
| Matthee, H | 1 |
| Nikol, M | 1 |
| Veliev, NM | 1 |
4 reviews available for 4-nitroquinoline-1-oxide and Abnormalities, Autosome
| Article | Year |
|---|---|
Transgenerational transmission of radiation- and chemically induced tumors and congenital anomalies in mice: studies of their possible relationship to induced chromosomal and molecular changes.
Topics: 4-Nitroquinoline-1-oxide; Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Animals; Ca | 2004 |
Actions of 4-nitroquinoline 1-oxide on eucaryotic cells: molecular and cellular studies.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Cell Cycle; Cell Survival; Cells; Cells, Cultured; C | 1981 |
Molecular biology of the carcinogen, 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Adenine; Animals; Bacteria; Bacteriophages; Base Sequence; Carcinogens; Ce | 1976 |
Mechanisms of induction of specific chromosomal alterations.
Topics: 4-Nitroquinoline-1-oxide; Animals; Chromosome Aberrations; DNA Damage; DNA Repair; DNA Replication; | 1990 |
60 other studies available for 4-nitroquinoline-1-oxide and Abnormalities, Autosome
| Article | Year |
|---|---|
Whole genome sequencing analysis of small and large colony mutants from the mouse lymphoma assay.
Topics: 4-Nitroquinoline-1-oxide; Animals; Chromosome Aberrations; DNA Copy Number Variations; Leukemia L517 | 2018 |
Antigenotoxic effects of resveratrol: assessment of in vitro and in vivo response.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antimutagenic Agents; Bone Marrow Cells; Chromosome Aberrations; | 2016 |
The clastogenicity of 4NQO is cell-type dependent and linked to cytotoxicity, length of exposure and p53 proficiency.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Cell Line, Tumor; Chromosome Aberrations; Comet Assa | 2016 |
Integration of Pig-a, micronucleus, chromosome aberration, and Comet assay endpoints in a 28-day rodent toxicity study with 4-nitroquinoline-1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Brain; Calibration; CD59 Antigens; Chromosome Aberrations; Comet | 2011 |
Chromosomal instability in B-lymphoblasotoid cell lines from Werner and Bloom syndrome patients.
Topics: 4-Nitroquinoline-1-oxide; B-Lymphocytes; Bloom Syndrome; Camptothecin; Carcinogens; Case-Control Stu | 2002 |
Antigenotoxic potential of glucomannan on four model test systems.
Topics: 4-Nitroquinoline-1-oxide; Aminacrine; Animals; Antimutagenic Agents; Candida; Cell Division; Chlamyd | 2004 |
DNA repair and chromosome aberrations: the effect of cytosine arabinoside on the frequency of chromosome aberrations induced by radiation and chemicals.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Aberrations; Chromosomes; Cytarabine; DNA Repair; Humans; In Vi | 1980 |
[Interferon as a protector in human cells treated with 4-nitroquinoline-1-oxide].
Topics: 4-Nitroquinoline-1-oxide; Cell Division; Cells, Cultured; Chromosome Aberrations; Diploidy; Dose-Res | 1981 |
Neuroblast of the grasshopper embryo as a new mutagen test system. II. Chromosome breakage induced by in vitro exposure of embryos to the direct-acting mutagens 4NQO, MNNG, adriamycin, and bleomycin.
Topics: 4-Nitroquinoline-1-oxide; Animals; Bleomycin; Chromosome Aberrations; Chromosomes; Doxorubicin; Gras | 1982 |
[Antimutagenic action of interferon in human cells exposed to fast neutrons and 4-nitroquinoline-1-oxide].
Topics: 4-Nitroquinoline-1-oxide; Cells, Cultured; Chromosome Aberrations; Fast Neutrons; Humans; Interferon | 1982 |
An intestinal cell-mediated chromosome aberration test for the detection of genotoxic agents.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Benzopyrenes; B | 1983 |
Chromosomal hypersensitivity in mutant M10 and Q31 mouse cells exposed to ultraviolet radiation (UV) and 4-nitroquinoline-1-oxide (4NQO).
Topics: 4-Nitroquinoline-1-oxide; Animals; Cells, Cultured; Chromosome Aberrations; Leukemia L5178; Mice; Ni | 1983 |
Clastogenic effect of 4-nitroquinoline-1-oxide on swine urothelial cells in culture.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Chromosome Aberrations; Dose-Response Relationship, | 1980 |
[Number of chromosome aberrations induced by chemical carcinogens in the cells of patients with 2 forms of xeroderma pigmentosum].
Topics: 4-Nitroquinoline-1-oxide; Benz(a)Anthracenes; Carcinogens; Cell Cycle; Chromosome Aberrations; Human | 1980 |
Effects of caffeine-induced defective DNA replication on SCE and chromosome aberrations produced by alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; B-Lymphocytes; Caffeine; Cells, Cultured; Chromosome Ab | 1980 |
The induction of chromosome-type aberrations in G1 by methyl methanesulfonate and 4-nitroquinoline-N,-oxide, and the non-requirement of an S-phase for their production.
Topics: 4-Nitroquinoline-1-oxide; Cells, Cultured; Chromosome Aberrations; Chromosomes; Cytarabine; Drug The | 1981 |
Morphologic transformation and chromosomal changes induced by chemical carcinogens in skin fibroblasts from patients with familial adenomatosis coli.
Topics: 4-Nitroquinoline-1-oxide; Adenoma; Cell Count; Cell Division; Cell Transformation, Neoplastic; Cells | 1982 |
Repair of chromosome damage induced by X-irradiation during G2 phase in a line of normal human fibroblasts and its malignant derivative.
Topics: 4-Nitroquinoline-1-oxide; Caffeine; Catalase; Cell Line; Cell Transformation, Neoplastic; Chromosome | 1982 |
Characterization of a rat oral squamous cell carcinoma cell line UHG-RaC '93 induced by 4-nitroquinoline-1-oxide in vivo.
Topics: 4-Nitroquinoline-1-oxide; Animals; Carcinogens; Carcinoma, Squamous Cell; Cells, Cultured; Chromosom | 1995 |
Inorganic cadmium increases the frequency of chemically induced chromosome aberrations in cultured mammalian cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cadmium; Cells, Cultured; CHO Cells; Chromosome Aberrations; Cric | 1993 |
Potentiating effects of organomercuries on clastogen-induced chromosome aberrations in cultured Chinese hamster cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Chi-Square Distribution; CHO Cells; Chromosome Aberrations; Crice | 1993 |
Loss of expression of basement membrane proteins reflects anomalies of chromosomes 3 and 12 in the rat 4-nitroquinoline-N-oxide model of oral carcinogenesis.
Topics: 3T3 Cells; 4-Nitroquinoline-1-oxide; Animals; Basement Membrane; Carcinoma; Carcinoma, Squamous Cell | 1995 |
Immortalization of normal human fibroblasts by treatment with 4-nitroquinoline 1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Cells, Cultured; Cellular Senescence; Chromosome Aberrations; DNA Fingerpr | 1993 |
Monitoring of induced chromosomal aberrations in S. cerevisiae in agarose gels by pulsed field gel electrophoresis.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Aberrations; DNA, Fungal; Electrophoresis, Gel, Pulsed-Field; M | 1995 |
A critical evaluation of centromeric labeling to distinguish micronuclei induced by chromosomal loss and breakage in vitro.
Topics: 4-Nitroquinoline-1-oxide; Aneuploidy; Autoantibodies; B-Lymphocytes; Cell Line; Centromere; Chromoso | 1997 |
Werner and Bloom helicases are involved in DNA repair in a complementary fashion.
Topics: 4-Nitroquinoline-1-oxide; Adenosine Triphosphatases; Amino Acid Sequence; Animals; B-Lymphocytes; Bl | 2002 |
Effects of various chemical agents on sister chromatid exchanges, chromosome aberrations, and DNA repair in normal and abnormal human lymphoid cell lines.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Cell Survival; Chromosome Aberrations; Crossing Over, | 1979 |
The relevance of a caffeine post-treatment to SCE incidence induced in Chinese hamster cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; Cell Line; Chromosome Aberrations; Chromosomes; Cisplat | 1979 |
Effects of arginine deprivation upon chromosome aberrations, sces and survival of cho cells treated with mutagenic agents.
Topics: 4-Nitroquinoline-1-oxide; Animals; Arginine; Cell Line; Cell Survival; Chromosome Aberrations; Chrom | 1979 |
Effects of chemicals on the frequency of sister chromatid exchanges and chromosome aberrations in normal and Bloom's syndrome lymphocytes.
Topics: 4-Nitroquinoline-1-oxide; Adult; Caffeine; Chromosome Aberrations; Crossing Over, Genetic; Humans; L | 1979 |
Sister chromatid exchange and chromosome aberration analysis with the use of several carcinogens and noncarcinogens.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Acridines; Benzop | 1977 |
Differential sensitivity of Xeroderma pigmentosum cells of different repair capacities towards the chromosome breaking action of carcinogens and mutagens.
Topics: 4-Nitroquinoline-1-oxide; Acetoxyacetylaminofluorene; Carcinogens; Cells, Cultured; Chromosome Aberr | 1977 |
Chromosomal effects of carcinogens and non-carcinogens on WI-38 after short term exposures with and without metabolic activation.
Topics: 4-Nitroquinoline-1-oxide; Benzopyrenes; Caffeine; Cell Line; Chromosome Aberrations; Chromosomes; Di | 1977 |
Carcinogenesis in tissue culture. 28. Comparison of various effects of a chemical carcinogen, 4-nitroquinoline I-oxide, on normal human cells and on normal mouse cells in culture.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; | 1977 |
Comparison of mutagenicity and inducibility of DNA single-strand breaks and chromosome aberrations in cultured mouse cells by potent mutagens.
Topics: 4-Nitroquinoline-1-oxide; Animals; Azaguanine; Cell Line; Centrifugation, Density Gradient; Chromoso | 1977 |
Reduced DNA repair capacity and increased cytotoxicity following split doses of the mutagen 4-nitroquinoline-1-oxide in cultured human cells.
Topics: 4-Nitroquinoline-1-oxide; Cell Survival; Cells, Cultured; Chromosome Aberrations; Clone Cells; DNA R | 1975 |
Cytogenetic analysis of oral and cutaneous squamous cell carcinomas in the rat.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinoma, Squamous Cell; Cell | 1975 |
Problems of testing drugs for potential mutagenicity.
Topics: 4-Nitroquinoline-1-oxide; Animals; Biotransformation; Carcinogens; Chromosome Aberrations; Dimethyln | 1976 |
Cytomegalovirus-enhanced induction of chromosome aberrations in human peripheral blood lymphocytes treated with potent genotoxic agents.
Topics: 4-Hydroxyaminoquinoline-1-oxide; 4-Nitroquinoline-1-oxide; Antigens, Viral; Bleomycin; Cells, Cultur | 1992 |
Factors underlying variation in spontaneous and clastogen-induced sister chromatid exchanges and chromosome breakage frequencies.
Topics: 4-Nitroquinoline-1-oxide; Adult; Alkylating Agents; Bleomycin; Chromosome Aberrations; Female; Human | 1990 |
Spontaneous and clastogen induced chromosomal breakage in scleroderma.
Topics: 4-Nitroquinoline-1-oxide; Adult; Aged; Bleomycin; Cells, Cultured; Chromosome Aberrations; Chromosom | 1991 |
High recurrence of rearrangements involving chromosome 14 in an ataxia telangiectasia lymphoblastoid cell line and in its mutagen-treated derivatives.
Topics: 4-Nitroquinoline-1-oxide; Adult; Antigens, Viral; Ataxia Telangiectasia; Cell Line, Transformed; Cel | 1991 |
Effect of pH on the activity and stability of clastogens in the in vitro chromosomal aberration test with Chinese hamster ovary K1 cells.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Benzo(a)pyrene; Cells, Cultured | 1991 |
Influence of treatment to sacrifice time and the presence of BrdUrd on chemically-induced aberration rates in mouse marrow cells.
Topics: 4-Nitroquinoline-1-oxide; 9,10-Dimethyl-1,2-benzanthracene; Animals; Bone Marrow Cells; Bromodeoxyur | 1990 |
Modification of DNA repair by human interferons.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Aberrations; DNA Repair; Fast Neutrons; Gamma Rays; Humans; In | 1990 |
Spontaneous and induced chromosomal instability in Werner syndrome.
Topics: 4-Nitroquinoline-1-oxide; Adult; Bleomycin; Cells, Cultured; Chromosome Aberrations; Epoxy Compounds | 1988 |
Cytogenetical characterization of UV-sensitive repair-deficient CHO cell line 43-3B. II. Induction of cell killing, chromosomal aberrations and sister-chromatid exchanges by 4NQO, mono- and bi-functional alkylating agents.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Animals; Cell Line; Cell Survival; Chromosome Aberratio | 1989 |
Cytogenetical characterisation of Chinese hamster 43-3B transferants with the amplified or non-amplified human DNA repair gene ERCC-1.
Topics: 4-Nitroquinoline-1-oxide; Alkylating Agents; Animals; Cell Line; Cell Survival; Chromosome Aberratio | 1989 |
Enhancing effects of cinoxate and methyl sinapate on the frequencies of sister-chromatid exchanges and chromosome aberrations in cultured mammalian cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Chromosome Aberrations; Cinnamates; Cricetinae; DNA Re | 1989 |
Genotoxic potency of three quinoline compounds evaluated in vivo in mouse marrow cells.
Topics: 4-Nitroquinoline-1-oxide; Animals; Bone Marrow; Cell Line; Chemical Phenomena; Chemistry; Chromosome | 1989 |
Spontaneous and 4-nitroquinoline 1-oxide-induced G2 chromosome aberrations in lymphoblasts from familial melanoma patients.
Topics: 4-Nitroquinoline-1-oxide; Chromosome Aberrations; Humans; Interphase; Lymphocytes; Melanoma; Neoplas | 1989 |
Toxic effects of chemicals on mouse post-blastocyst development--a trial to establish a testing system for embryotoxicity.
Topics: 4-Nitroquinoline-1-oxide; Animals; Antibiotics, Antineoplastic; Blastocyst; Bleomycin; Chromosome Ab | 1985 |
Chemical and viral transformation of cultured skin fibroblasts from patients with familial polyposis coli.
Topics: 4-Nitroquinoline-1-oxide; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Chromosom | 1988 |
Carcinogenicity of betel quid. III. Enhancement of 4-nitroquinoline-1-oxide- and N-2-fluorenylacetamide-induced carcinogenesis in rats by subsequent administration of betel nut.
Topics: 2-Acetylaminofluorene; 4-Nitroquinoline-1-oxide; Animals; Areca; Chromosome Aberrations; Cocarcinoge | 1986 |
Relationship between cellular levels of beta-carotene and sensitivity to genotoxic agents.
Topics: 4-Nitroquinoline-1-oxide; Animals; beta Carotene; Carcinogens; Carotenoids; Cell Survival; Chromosom | 1986 |
Chromosomal aberrations in an ionizing radiation-sensitive mouse lymphoma mutant cells exposed to gamma-rays and 4-nitroquinoline-1-oxide.
Topics: 4-Nitroquinoline-1-oxide; Animals; Cell Line; Chromosome Aberrations; Gamma Rays; Lymphoma; Mutation | 1986 |
Chromosomal instability in mutagen-sensitive mutants isolated from mouse lymphoma L5178Y cells. II. Abnormal induction of sister-chromatid exchanges and chromosomal aberrations by mutagens in an ionizing radiation-sensitive mutant (M10) and an alkylating
Topics: 4-Nitroquinoline-1-oxide; Animals; Caffeine; Cell Line; Cell Survival; Chromosome Aberrations; Chrom | 1987 |
Suppressive effect of novobiocin on the frequency of chromosome-type aberrations induced by ara C in the G1 phase of human lymphocytes.
Topics: 4-Nitroquinoline-1-oxide; Adult; Age Factors; Child; Chromosome Aberrations; Cytarabine; Humans; Inf | 1988 |
Cytogenetic analyses utilizing various clastogens in two sibs with Fanconi anemia, their relatives, and control individuals.
Topics: 4-Nitroquinoline-1-oxide; Adult; Anemia, Aplastic; Bromodeoxyuridine; Cells, Cultured; Child; Child, | 1985 |
[Mechanism of the antimutagenic action of interferon: the capacity to protect the human cellular repair system].
Topics: 4-Nitroquinoline-1-oxide; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Dose-Response | 1985 |