Page last updated: 2024-08-23

4-ipomeanol and Lung Neoplasms

4-ipomeanol has been researched along with Lung Neoplasms in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's6 (54.55)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Boyd, MR; Reznik-Schüller, HM1
Devor, DE; Rehm, S1
Boyd, MR; Christian, MC; Donehower, RC; Ettinger, DS; Fishman, EK; Lubejko, BG; Noe, DA; Rowinsky, EK; Sartorius, SE1
Amin, S; Chang, L; Desai, D1
Gram, TE1
Christian, MC; Dearing, MP; Johnson, BE; Kasturi, VK; Kelley, MJ; Morton, TL; O'Neil, K; Piscitelli, SC; Russell, EK; Sladek, GG; Turner, GA1
Adelberg, S; Boyd, MR; Coudert, BP; Czerwinski, M; Eggleston, JC; Hubbard, WC; Litterst, CL; Liu, MC; McLemore, TL; McMahon, NA1
Boyd, MR; Chabner, BA; Christian, MC; Grieshaber, CK; Leyland-Jones, B; McLemore, TL; Smith, AC; Wittes, RE1
Boyd, MR; Falzon, M; McMahon, JB; Schuller, HM1
Barrett, D; Boyd, MR; el-Hawari, M; Grieshaber, CK; Kastello, MD; Smith, AC; Stedham, MA1
Breeze, R1

Reviews

4 review(s) available for 4-ipomeanol and Lung Neoplasms

ArticleYear
Metabolic basis for the pulmonary Clara cell as a target for pulmonary carcinogenesis.
    Toxicologic pathology, 1984, Volume: 12, Issue:1

    Topics: Animals; Biotransformation; Bronchi; Cricetinae; Cytochrome P-450 Enzyme System; Furans; Liver; Lung Neoplasms; Mice; Microsomes; Nitrosamines; Rabbits; Rats; Terpenes

1984
Chemically reactive intermediates and pulmonary xenobiotic toxicity.
    Pharmacological reviews, 1997, Volume: 49, Issue:4

    Topics: Animals; Anti-Infective Agents, Urinary; Antibiotics, Antineoplastic; Antineoplastic Agents; Antioxidants; Benzo(a)pyrene; Biotransformation; Bleomycin; Butylated Hydroxytoluene; Carcinogens; Cytochrome P-450 Enzyme System; Dichloroethylenes; DNA Adducts; Herbicides; Hyperoxia; Lung; Lung Neoplasms; Naphthalenes; Nitrofurantoin; Nitrosamines; Paraquat; Skatole; Terpenes; Xenobiotics

1997
4-Ipomeanol: a novel investigational new drug for lung cancer.
    Journal of the National Cancer Institute, 1989, Aug-02, Volume: 81, Issue:15

    Topics: Animals; Antineoplastic Agents; Drug Evaluation; Drug Evaluation, Preclinical; Humans; Lung Neoplasms; Terpenes

1989
Respiratory disease in adult cattle.
    The Veterinary clinics of North America. Food animal practice, 1985, Volume: 1, Issue:2

    Topics: Alveolitis, Extrinsic Allergic; Anaphylaxis; Animals; Brassica; Cattle; Cattle Diseases; Chronic Disease; Diagnosis, Differential; Granuloma; Lung Neoplasms; Manure; Monoterpenes; Nitrogen Dioxide; Plant Poisoning; Pneumonia; Pneumonia, Atypical Interstitial, of Cattle; Pulmonary Fibrosis; Respiratory Distress Syndrome; Respiratory Tract Diseases; Smog; Terpenes; Zinc Oxide

1985

Trials

2 trial(s) available for 4-ipomeanol and Lung Neoplasms

ArticleYear
Phase I and pharmacological study of the pulmonary cytotoxin 4-ipomeanol on a single dose schedule in lung cancer patients: hepatotoxicity is dose limiting in humans.
    Cancer research, 1993, Apr-15, Volume: 53, Issue:8

    Topics: Adult; Aged; Cytotoxins; Drug Administration Schedule; Female; Humans; Kidney; Liver; Lung; Lung Neoplasms; Male; Middle Aged; Terpenes

1993
Phase I study of a five-day dose schedule of 4-Ipomeanol in patients with non-small cell lung cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1998, Volume: 4, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Administration Schedule; Female; Humans; Lung Diseases; Lung Neoplasms; Male; Middle Aged; Partial Thromboplastin Time; Terpenes

1998

Other Studies

5 other study(ies) available for 4-ipomeanol and Lung Neoplasms

ArticleYear
Acute effects of 4-ipomeanol on experimental lung tumors with bronchiolar or alveolar cell features in Syrian hamsters or C3H/HeNCr mice.
    Journal of cancer research and clinical oncology, 1993, Volume: 120, Issue:1-2

    Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Antineoplastic Agents; Carcinoma, Adenosquamous; Cricetinae; Female; Lung Neoplasms; Male; Mesocricetus; Mice; Mice, Inbred C3H; Terpenes

1993
Synthesis and bioassay of 4-ipomeanol analogs as potential chemopreventive agents against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced tumorigenicity in A/J mice.
    Cancer letters, 1996, Nov-29, Volume: 108, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinogens; Lung Neoplasms; Mice; Mice, Inbred A; Neoplasms, Experimental; Nitrosamines; Terpenes

1996
Metabolic activation of 4-ipomeanol in human lung, primary pulmonary carcinomas, and established human pulmonary carcinoma cell lines.
    Journal of the National Cancer Institute, 1990, Sep-05, Volume: 82, Issue:17

    Topics: Biotransformation; Carcinoma; Cytochrome P-450 Enzyme System; Humans; Lung; Lung Neoplasms; Terpenes; Toxins, Biological; Tumor Cells, Cultured

1990
Metabolic activation and cytotoxicity of 4-ipomeanol in human non-small cell lung cancer lines.
    Cancer research, 1986, Volume: 46, Issue:7

    Topics: Biotransformation; Bronchi; Carcinoma, Small Cell; Cell Line; Cell Survival; Humans; Lung Neoplasms; Mixed Function Oxygenases; Protein Binding; Proteins; Pulmonary Alveoli; Terpenes

1986
Preclinical toxicology studies of 4-ipomeanol: a novel candidate for clinical evaluation in lung cancer.
    Cancer treatment reports, 1987, Volume: 71, Issue:12

    Topics: Animals; Antineoplastic Agents; Dogs; Drug Evaluation, Preclinical; Drug Tolerance; Female; Lethal Dose 50; Lung; Lung Neoplasms; Male; Mice; Rats; Terpenes

1987