Compounds > 4-iodo-2,5-dimethoxyphenylisopropylamine
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4-iodo-2,5-dimethoxyphenylisopropylamine and Pregnancy

4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Pregnancy in 17 studies

4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Haloperidol and clozapine treatment disrupted pup approach, pup retrieval, pup licking and nest building."1.35The receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: a double dissociation between dopamine D(2) and 5-HT(2A/2C) receptors. ( Li, M; Zhao, C, 2009)
" We performed acute dose-response and time course behavioral studies in 1-day-old rats with the putative selective agonists 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) (5-HT1A), 5-methoxy-3(1,2,3,6-tetrahydropyridin-4-yl)1H-indole (RU 24969) (5-HT1B), and (+-)1-(2,5-dimethoxy-4-iodo-phenyl aminopropane)-2 (DOI) (5-HT2/1C)."1.28Serotonin receptor ontogeny: effects of agonists in 1-day-old rats. ( Pranzatelli, MR, 1992)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (58.82)18.2507
2000's4 (23.53)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ishiguro, T1
Sakata-Haga, H1
Fukui, Y1
Bras, H1
Gaytán, SP1
Portalier, P1
Zanella, S1
Pásaro, R1
Coulon, P1
Hilaire, G1
Zhao, C1
Li, M1
Oufkir, T2
Arseneault, M1
Sanderson, JT1
Vaillancourt, C2
el Mansari, M1
Radja, F2
Ferron, A1
Reader, TA2
Molina-Holgado, E1
Descarries, L1
Cabrera, TM1
Battaglia, G2
Johansson-Wallsten, CE1
Berg, M1
Meyerson, BJ1
Laprade, N1
Soghomonian, JJ1
Maswood, N1
Uphouse, L1
Bollweg, G1
Sparber, SB1
Jahn, GA1
Kalia, V1
Hole, D1
Wilson, CA1
Deis, RP1
Fiorica-Howells, E1
Maroteaux, L1
Gershon, MD1
Cabrera-Vera, TM1
Van De Kar, LD1
Mitchell, JB1
Betito, K1
Rowe, W1
Boksa, P1
Meaney, MJ1
Mokler, DJ1
Sullivan, SA1
Winterson, BJ1
Pranzatelli, MR1

Other Studies

17 other studies available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Pregnancy

ArticleYear
A 5-HT2A/2C receptor agonist, 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane, mitigates developmental neurotoxicity of ethanol to serotonergic neurons.
    Congenital anomalies, 2016, Volume: 56, Issue:4

    Topics: Amphetamines; Animals; Biogenic Monoamines; Body Weight; Brain; Cell Count; Cell Differentiation; Et

2016
Prenatal activation of 5-HT2A receptor induces expression of 5-HT1B receptor in phrenic motoneurons and alters the organization of their premotor network in newborn mice.
    The European journal of neuroscience, 2008, Volume: 28, Issue:6

    Topics: Amphetamines; Animals; Animals, Newborn; Embryo, Mammalian; Female; Ketanserin; Mice; Mice, Inbred C

2008
The receptor mechanisms underlying the disruptive effects of haloperidol and clozapine on rat maternal behavior: a double dissociation between dopamine D(2) and 5-HT(2A/2C) receptors.
    Pharmacology, biochemistry, and behavior, 2009, Volume: 93, Issue:4

    Topics: Amphetamines; Animals; Antipsychotic Agents; Clozapine; Dopamine Agonists; Dopamine Antagonists; Dos

2009
The 5-HT 2A serotonin receptor enhances cell viability, affects cell cycle progression and activates MEK-ERK1/2 and JAK2-STAT3 signalling pathways in human choriocarcinoma cell lines.
    Placenta, 2010, Volume: 31, Issue:5

    Topics: Adult; Amphetamines; Cell Cycle; Cell Line, Tumor; Cell Survival; Choriocarcinoma; Chorionic Villi;

2010
Phosphorylation of JAK2 by serotonin 5-HT (2A) receptor activates both STAT3 and ERK1/2 pathways and increases growth of JEG-3 human placental choriocarcinoma cell.
    Placenta, 2011, Volume: 32, Issue:12

    Topics: Amphetamines; Butadienes; Carbazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Choriocar

2011
Hypersensitivity to serotonin and its agonists in serotonin-hyperinnervated neostriatum after neonatal dopamine denervation.
    European journal of pharmacology, 1994, Aug-11, Volume: 261, Issue:1-2

    Topics: Amphetamines; Animals; Animals, Newborn; Autoradiography; Behavior, Animal; Denervation; Dopamine; E

1994
Delayed decreases in brain 5-hydroxytryptamine2A/2C receptor density and function in male rat progeny following prenatal fluoxetine.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:2

    Topics: Adrenocorticotropic Hormone; Amphetamines; Animals; Cerebral Cortex; Female; Fluoxetine; Hypothalamu

1994
The effects of long-term treatment with the 5-HT1A receptor agonist 8-OH-DPAT and the 5-HT2/1C receptor agonist DOI in the neonatal rat.
    European journal of pharmacology, 1993, Oct-19, Volume: 243, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Animals, Newborn; Dose-Response Relat

1993
Dopamine receptor agonists regulate levels of the serotonin 5-HT2A receptor and its mRNA in a subpopulation of rat striatal neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1996, Jun-01, Volume: 16, Issue:11

    Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; Adrenergic Agents; Amphetamines; Animals

1996
Modulation of the behavioral effects of 8-OH-DPAT by estrogen and DOI.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 58, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Body Temperature; E

1997
Relationships between midembryonic 5-HT2 agonist and/or antagonist exposure and detour learning by chickens.
    Pharmacology, biochemistry, and behavior, 1998, Volume: 60, Issue:1

    Topics: Amphetamines; Animals; Behavior, Animal; Body Weight; Chick Embryo; Chickens; Female; Humans; Learni

1998
Receptors and neurotransmitters involved in the dual modulation of prolactin release by the serotoninergic system in pregnant and lactating rats.
    Journal of reproduction and fertility, 1999, Volume: 116, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergi

1999
Serotonin and the 5-HT(2B) receptor in the development of enteric neurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2000, Jan-01, Volume: 20, Issue:1

    Topics: Age Factors; Amphetamines; Animals; Antibodies; Antigens, Differentiation; Cell Differentiation; Cel

2000
Prenatal cocaine exposure potentiates 5-HT(2a) receptor function in male and female rat offspring.
    Synapse (New York, N.Y.), 2000, Mar-01, Volume: 35, Issue:3

    Topics: Adrenocorticotropic Hormone; Amphetamines; Animals; Cerebral Cortex; Cocaine; Corticosterone; Female

2000
Serotonergic regulation of type II corticosteroid receptor binding in hippocampal cell cultures: evidence for the importance of serotonin-induced changes in cAMP levels.
    Neuroscience, 1992, Volume: 48, Issue:3

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amphetamines; Animals; Cells, Cultured; Cyclic AMP; Female;

1992
Behaviors induced by 5-hydroxytryptophan in neonatal, preweaning, postweaning, and adult Sprague-Dawley rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals,

1992
Serotonin receptor ontogeny: effects of agonists in 1-day-old rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals, Newborn; Female; Indo

1992