4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Parkinson Disease in 3 studies
4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (33.33) | 29.6817 |
2010's | 2 (66.67) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Andrzejewski, K | 1 |
KaczyĆska, K | 1 |
Zaremba, M | 1 |
Wang, S | 1 |
Zhang, QJ | 1 |
Liu, J | 1 |
Ali, U | 1 |
Wu, ZH | 1 |
Chen, L | 1 |
Gui, ZH | 1 |
Wang, Y | 1 |
Hui, YP | 1 |
McFarland, K | 1 |
Price, DL | 1 |
Bonhaus, DW | 1 |
3 other studies available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Parkinson Disease
Article | Year |
---|---|
Serotonergic system in hypoxic ventilatory response in unilateral rat model of Parkinson's disease.
Topics: Amphetamines; Animals; Brain Stem; Corpus Striatum; Hypoxia; Ketanserin; Male; Organ Specificity; Ox | 2017 |
In vivo effects of activation and blockade of 5-HT(2A/2C) receptors in the firing activity of pyramidal neurons of medial prefrontal cortex in a rodent model of Parkinson's disease.
Topics: Action Potentials; Amphetamines; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; | 2009 |
Pimavanserin, a 5-HT2A inverse agonist, reverses psychosis-like behaviors in a rodent model of Parkinson's disease.
Topics: Amphetamine; Amphetamines; Animals; Antipsychotic Agents; Behavior, Animal; Central Nervous System S | 2011 |