Page last updated: 2024-10-21

4-iodo-2,5-dimethoxyphenylisopropylamine and Injuries, Spinal Cord

4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Injuries, Spinal Cord in 5 studies

4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.

Research Excerpts

ExcerptRelevanceReference
" To probe the role of 5-HT2R in this increased amplitude, dose-response studies were done with the selective antagonists mianserin or LY53857 and the 5-HT2R agonist (+/-)-1-(2,5-Dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI)."1.34Up-regulation of 5-HT2 receptors is involved in the increased H-reflex amplitude after contusive spinal cord injury. ( Johnson, CS; Lee, JK; Wrathall, JR, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Basura, GJ2
Nantwi, KD1
Goshgarian, HG2
Harvey, PJ1
Li, X1
Li, Y1
Bennett, DJ1
Lee, JK1
Johnson, CS1
Wrathall, JR1
Kim, D1
Adipudi, V1
Shibayama, M1
Giszter, S1
Tessler, A1
Murray, M1
Simansky, KJ1
Zhou, SY1

Other Studies

5 other studies available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Injuries, Spinal Cord

ArticleYear
Theophylline-induced respiratory recovery following cervical spinal cord hemisection is augmented by serotonin 2 receptor stimulation.
    Brain research, 2002, Nov-22, Volume: 956, Issue:1

    Topics: Action Potentials; Amphetamines; Animals; Cervical Vertebrae; Diaphragm; Drug Synergism; Female; Imm

2002
5-HT2 receptor activation facilitates a persistent sodium current and repetitive firing in spinal motoneurons of rats with and without chronic spinal cord injury.
    Journal of neurophysiology, 2006, Volume: 96, Issue:3

    Topics: Amphetamines; Animals; Cerebrospinal Fluid; Female; In Vitro Techniques; Motor Neurons; Patch-Clamp

2006
Up-regulation of 5-HT2 receptors is involved in the increased H-reflex amplitude after contusive spinal cord injury.
    Experimental neurology, 2007, Volume: 203, Issue:2

    Topics: Amphetamines; Animals; Contusions; Ergolines; Female; H-Reflex; Immunohistochemistry; Injections, Sp

2007
Direct agonists for serotonin receptors enhance locomotor function in rats that received neural transplants after neonatal spinal transection.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1999, Jul-15, Volume: 19, Issue:14

    Topics: Amphetamines; Animals; Animals, Newborn; Fenfluramine; Fetal Tissue Transplantation; Motor Activity;

1999
Serotonin(2) receptors mediate respiratory recovery after cervical spinal cord hemisection in adult rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 2001, Volume: 91, Issue:6

    Topics: Amphetamines; Animals; Asphyxia; Cervical Vertebrae; Female; Ketanserin; Phrenic Nerve; Pyrazines; R

2001