4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Habit Chorea in 4 studies
4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Donepezil is an acetylcholinesterase inhibitor approved for use in mild to moderate Alzheimer's disease." | 5.32 | Effects of donepezil on DOI-induced head twitch response in mice: implications for Tourette syndrome. ( Hayslett, RL; Tizabi, Y, 2003) |
| "We previously reported a novel psychobiotic strain of Lactobacillus plantarum PS128 (PS128) which could ameliorate anxiety-like& depression-like behaviors and modulate cerebral dopamine (DA) and serotonin (5-HT) in mice." | 1.51 | Lactobacillus plantarum PS128 ameliorates 2,5-Dimethoxy-4-iodoamphetamine-induced tic-like behaviors via its influences on the microbiota-gut-brain-axis. ( Cheng, YF; Hsu, CC; Jeng, OJ; Lee, WT; Li, SW; Liao, JF; Tsai, YC; Wang, S; Wu, CC, 2019) |
| "Thus, mouse strains selected for a particular trait may be leveraged to generate hypothesis-driven studies aimed at clarifying the potential role played by the environment in modulating the exhibition of the symptoms of interest." | 1.40 | A behavioural test battery to investigate tic-like symptoms, stereotypies, attentional capabilities, and spontaneous locomotion in different mouse strains. ( Ceci, C; Laviola, G; Macrì, S; Proietti Onori, M, 2014) |
| "Donepezil is an acetylcholinesterase inhibitor approved for use in mild to moderate Alzheimer's disease." | 1.32 | Effects of donepezil on DOI-induced head twitch response in mice: implications for Tourette syndrome. ( Hayslett, RL; Tizabi, Y, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liao, JF | 1 |
| Cheng, YF | 1 |
| Li, SW | 1 |
| Lee, WT | 1 |
| Hsu, CC | 1 |
| Wu, CC | 1 |
| Jeng, OJ | 1 |
| Wang, S | 1 |
| Tsai, YC | 1 |
| Proietti Onori, M | 1 |
| Ceci, C | 1 |
| Laviola, G | 1 |
| Macrì, S | 1 |
| Canal, CE | 1 |
| Booth, RG | 1 |
| Morgan, D | 1 |
| Hayslett, RL | 1 |
| Tizabi, Y | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot Examination of Galantamine in the Management of Tic Disorders[NCT00226824] | Phase 4 | 1 participants (Actual) | Interventional | 2005-09-30 | Terminated (stopped due to Unable to recruit subjects into the trial.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Habit Chorea
| Article | Year |
|---|---|
Lactobacillus plantarum PS128 ameliorates 2,5-Dimethoxy-4-iodoamphetamine-induced tic-like behaviors via its influences on the microbiota-gut-brain-axis.
Topics: Amphetamines; Animals; Brain; Corpus Striatum; Dopamine; Gastrointestinal Microbiome; Haloperidol; L | 2019 |
A behavioural test battery to investigate tic-like symptoms, stereotypies, attentional capabilities, and spontaneous locomotion in different mouse strains.
Topics: Amphetamine; Amphetamines; Animals; Attention; Central Nervous System Stimulants; Circadian Rhythm; | 2014 |
Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model.
Topics: Amphetamines; Animals; Dose-Response Relationship, Drug; Drug Interactions; Dyskinesia, Drug-Induced | 2013 |
Effects of donepezil on DOI-induced head twitch response in mice: implications for Tourette syndrome.
Topics: Amphetamines; Animals; Donepezil; Drug Synergism; Head Movements; Indans; Male; Mecamylamine; Mice; | 2003 |