4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Glioma in 4 studies
4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Excerpt | Relevance | Reference |
|---|---|---|
| " The dose-response curve for 5-HT was shifted 9-fold to the left compared to controls, and the Vmax value was also significantly enhanced." | 1.29 | Dexamethasone potentiates serotonin-2 receptor-mediated intracellular Ca2+ mobilization in C6 glioma cells. ( Kagaya, A; Mikuni, M; Muraoka, S; Saitoh, K; Takahashi, K, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muraoka, S | 1 |
| Mikuni, M | 1 |
| Kagaya, A | 1 |
| Saitoh, K | 1 |
| Takahashi, K | 1 |
| Garcia, MC | 2 |
| Kim, HY | 2 |
| Kim, KY | 1 |
| Hough, C | 1 |
| Miller, KJ | 1 |
| Gonzalez, HA | 1 |
4 other studies available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Glioma
| Article | Year |
|---|---|
Dexamethasone potentiates serotonin-2 receptor-mediated intracellular Ca2+ mobilization in C6 glioma cells.
Topics: Amphetamines; Animals; Calcium; Dexamethasone; Glioma; Ketanserin; Rats; Receptors, Serotonin; Serot | 1993 |
Mobilization of arachidonate and docosahexaenoate by stimulation of the 5-HT2A receptor in rat C6 glioma cells.
Topics: Amphetamines; Animals; Arachidonic Acid; Docosahexaenoic Acids; Glioma; Rats; Serotonin Receptor Ago | 1997 |
Effects of chronic ethanol on the mobilization of arachidonate and docosahexaenoate stimulated by the type 2A serotonin receptor agonist (+/-)-2,5-dimethoxy-4-iodoamphetamine hydrochloride in C6 glioma cells.
Topics: Amphetamines; Animals; Arachidonic Acid; Astrocytes; Brain Neoplasms; Cell Survival; Docosahexaenoic | 1997 |
Serotonin 5-HT2A receptor activation inhibits cytokine-stimulated inducible nitric oxide synthase in C6 glioma cells.
Topics: Amphetamines; Animals; Cytokines; Enzyme Induction; Gene Expression Regulation, Neoplastic; Glioma; | 1998 |