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4-iodo-2,5-dimethoxyphenylisopropylamine and Diabetic Neuropathies

4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Diabetic Neuropathies in 1 studies

4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.

Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)

Research Excerpts

ExcerptRelevanceReference
"The streptozotocin-induced diabetic rat model was used to compare the efficacy of duloxetine, 5-HT, the 5-HT(2A) receptor agonist [1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI)] and two antagonists (ketanserin and pruvanserin) on tactile allodynia."3.77A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy. ( Jolivalt, CG; Mixcoatl-Zecuatl, T, 2011)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mixcoatl-Zecuatl, T1
Jolivalt, CG1

Other Studies

1 other study available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Diabetic Neuropathies

ArticleYear
A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy.
    British journal of pharmacology, 2011, Volume: 164, Issue:1

    Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochlor

2011