4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Anesthesia Related Hyperthermia in 6 studies
4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with dantrolene completely abolished serotonin-induced MH." | 1.30 | Attenuation of serotonin-induced contractures in skeletal muscle from malignant hyperthermia-susceptible patients with dantrolene. ( Fiege, M; Köchling, A; Lambrecht, W; Scholz, J; Schulte am Esch, J; von Richthofen, V; Wappler, F, 1997) |
| "In pigs genetically susceptible to malignant hyperthermia (MH), it has been shown that serotonin (5-HT2) receptor agonists can induce MH and "psychotic" behaviour." | 1.29 | [Effects of serotonin 2 receptor agonists on skeletal muscle preparations in patients with a disposition toward malignant hyperthermia]. ( Köchling, A; Löscher, W; Roewer, N; Rumberger, E; Scholz, J; Schulte am Esch, J; Steinfath, M; Wappler, F, 1995) |
| "8 mg/kg, was fatal in 4 of 5 MH-susceptible pigs, whereas pigs injected with this dosage after pretreatment with ketanserin (0." | 1.28 | Pharmacodynamic effects of serotonin (5-HT) receptor ligands in pigs: stimulation of 5-HT2 receptors induces malignant hyperthermia. ( Bickhardt, K; Fredow, G; Ganter, M; Löscher, W; Witte, U, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (83.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gerbershagen, MU | 1 |
| Wappler, F | 5 |
| Fiege, M | 2 |
| Kolodzie, K | 1 |
| Weisshorn, R | 1 |
| Szafarczyk, W | 1 |
| Kudlik, C | 1 |
| Schulte Am Esch, J | 4 |
| Roewer, N | 2 |
| Köchling, A | 3 |
| Scholz, J | 4 |
| Steinfath, M | 3 |
| Rumberger, E | 1 |
| Löscher, W | 3 |
| Oppermann, S | 1 |
| von Richthofen, V | 2 |
| Lambrecht, W | 1 |
| Witte, U | 1 |
| Fredow, G | 1 |
| Ganter, M | 1 |
| Bickhardt, K | 1 |
1 trial available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Anesthesia Related Hyperthermia
| Article | Year |
|---|---|
Ritanserin attenuates the in vitro effects of the 5-HT2 receptor agonist DOI on skeletal muscles from malignant hyperthermia-susceptible patients.
Topics: Adolescent; Adult; Amphetamines; Female; Humans; In Vitro Techniques; Male; Malignant Hyperthermia; | 1997 |
5 other studies available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Anesthesia Related Hyperthermia
| Article | Year |
|---|---|
Effects of a 5HT(2) receptor agonist on anaesthetized pigs susceptible to malignant hyperthermia.
Topics: Amphetamines; Animals; Carbon Dioxide; Disease Susceptibility; Malignant Hyperthermia; Partial Press | 2003 |
[Effects of serotonin 2 receptor agonists on skeletal muscle preparations in patients with a disposition toward malignant hyperthermia].
Topics: Adolescent; Adult; Aged; Amphetamines; Child; Female; Humans; In Vitro Techniques; Male; Malignant H | 1995 |
Effects of the serotonin2 receptor agonist DOI on skeletal muscle specimens from malignant hyperthermia-susceptible patients.
Topics: Adolescent; Adult; Aged; Amphetamines; Animals; Cattle; Child; Child, Preschool; Halothane; Humans; | 1996 |
Attenuation of serotonin-induced contractures in skeletal muscle from malignant hyperthermia-susceptible patients with dantrolene.
Topics: Adolescent; Adult; Amphetamines; Child; Child, Preschool; Dantrolene; Humans; Malignant Hyperthermia | 1997 |
Pharmacodynamic effects of serotonin (5-HT) receptor ligands in pigs: stimulation of 5-HT2 receptors induces malignant hyperthermia.
Topics: Amphetamines; Anesthesia; Animals; Behavior, Animal; Brain Chemistry; Carbon Dioxide; Creatine Kinas | 1990 |