4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Alloxan Diabetes in 6 studies
4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The streptozotocin-induced diabetic rat model was used to compare the efficacy of duloxetine, 5-HT, the 5-HT(2A) receptor agonist [1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane hydrochloride (DOI)] and two antagonists (ketanserin and pruvanserin) on tactile allodynia." | 3.77 | A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy. ( Jolivalt, CG; Mixcoatl-Zecuatl, T, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Shuai, J | 1 |
| Gao, Y | 1 |
| Chen, L | 1 |
| Wang, Z | 1 |
| Li, JX | 1 |
| France, CP | 1 |
| Mixcoatl-Zecuatl, T | 1 |
| Jolivalt, CG | 1 |
| Miyata, S | 2 |
| Hirano, S | 2 |
| Kamei, J | 2 |
| Sikorski, BW | 1 |
| James, GM | 1 |
| Glance, SD | 1 |
| Hodgson, WC | 1 |
| King, RG | 1 |
6 other studies available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Alloxan Diabetes
| Article | Year |
|---|---|
Role of serotonin in regulation of pancreatic and mesenteric arterial function in diabetic mice.
Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Male; Mesenteric Arteries; Mice; Mice, Inbre | 2021 |
Food restriction and streptozotocin treatment decrease 5-HT1A and 5-HT2A receptor-mediated behavioral effects in rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal; Diabetes Mellitus, | 2008 |
A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropathy.
Topics: Amphetamines; Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Duloxetine Hydrochlor | 2011 |
Diabetes inhibits the DOI-induced head-twitch response in mice.
Topics: Amphetamines; Animals; Corticosterone; Diabetes Mellitus, Experimental; Head Movements; Ketanserin; | 2004 |
Involvement of diazepam-insensitive benzodiazepine receptors in the suppression of DOI-induced head-twitch responses in diabetic mice.
Topics: Amphetamines; Animals; Azides; Behavior, Animal; Benzodiazepines; Bicuculline; Diabetes Mellitus, Ex | 2006 |
Effect of endothelium on diabetes-induced changes in constrictor responses mediated by 5-hydroxytryptamine in rat aorta.
Topics: Amphetamines; Animals; Aorta; Arginine; Body Weight; Diabetes Mellitus, Experimental; Endothelium; I | 1993 |