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4-iodo-2,5-dimethoxyphenylisopropylamine and Aging

4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Aging in 9 studies

4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Ketanserin treatment lowered blood pressure consistently, and the ensuing hypotension was more pronounced in 14- and 24-month than in 4-month-old rats."5.29Aging enhances serotonergic cardiovascular blockade by ketanserin in conscious rats. ( Buñag, RD; Davidow, LW; Schmitz, TM, 1994)
"Ketanserin treatment lowered blood pressure consistently, and the ensuing hypotension was more pronounced in 14- and 24-month than in 4-month-old rats."1.29Aging enhances serotonergic cardiovascular blockade by ketanserin in conscious rats. ( Buñag, RD; Davidow, LW; Schmitz, TM, 1994)
" We performed acute dose-response and time course behavioral studies in 1-day-old rats with the putative selective agonists 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT) (5-HT1A), 5-methoxy-3(1,2,3,6-tetrahydropyridin-4-yl)1H-indole (RU 24969) (5-HT1B), and (+-)1-(2,5-dimethoxy-4-iodo-phenyl aminopropane)-2 (DOI) (5-HT2/1C)."1.28Serotonin receptor ontogeny: effects of agonists in 1-day-old rats. ( Pranzatelli, MR, 1992)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (66.67)18.2507
2000's0 (0.00)29.6817
2010's3 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cogger, VC1
Mitchell, SJ1
Warren, A1
de Cabo, R1
Le Couteur, DG1
Holm, P1
Ettrup, A1
Klein, AB1
Santini, MA1
El-Sayed, M1
Elvang, AB1
Stensbøl, TB1
Mikkelsen, JD1
Knudsen, GM1
Aznar, S1
Niimi, K1
Takahashi, E1
Itakura, C1
Robson, L1
Gower, AJ1
Kendall, DA1
Marsden, CA1
Davidow, LW1
Schmitz, TM1
Buñag, RD1
Jäkälä, P1
Riekkinen, P1
Fowler, CJ1
Sjöberg, E1
Tiger, G1
Mokler, DJ1
Sullivan, SA1
Winterson, BJ1
Pranzatelli, MR1

Other Studies

9 other studies available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Aging

ArticleYear
Age-related loss of responsiveness to 2,5-dimethoxy-4-iodoamphetamine in liver sinusoidal endothelial cells.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2014, Volume: 69, Issue:5

    Topics: Aging; Amphetamines; Animals; Endothelial Cells; Liver; Male; Mice; Mice, Inbred C57BL; Microcircula

2014
Plaque deposition dependent decrease in 5-HT2A serotonin receptor in AbetaPPswe/PS1dE9 amyloid overexpressing mice.
    Journal of Alzheimer's disease : JAD, 2010, Volume: 20, Issue:4

    Topics: Aging; Amphetamines; Amyloid beta-Protein Precursor; Aniline Compounds; Animals; Autoradiography; Ci

2010
Hallucinogenic 5-hydroxytryptamine 2A receptor agonist effects in senescence-accelerated mice.
    Experimental animals, 2010, Volume: 59, Issue:4

    Topics: Aging; Aging, Premature; Amphetamines; Animals; Behavior, Animal; CREB-Binding Protein; Disease Mode

2010
Age-related behavioural, neurochemical and radioligand binding changes in the central 5-HT system of Sprague-Dawley rats.
    Psychopharmacology, 1993, Volume: 113, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Behavior, Animal; Binding, Com

1993
Aging enhances serotonergic cardiovascular blockade by ketanserin in conscious rats.
    Aging (Milan, Italy), 1994, Volume: 6, Issue:4

    Topics: Aging; Amphetamines; Animals; Biguanides; Blood Pressure; Heart Rate; Ketanserin; Male; Rats; Rats,

1994
Combined cholinergic and 5-HT2 receptor activation suppresses thalamocortical oscillations in aged rats.
    Pharmacology, biochemistry, and behavior, 1997, Volume: 56, Issue:4

    Topics: Aging; Amphetamines; Animals; Cerebral Cortex; Cholinesterase Inhibitors; Drug Synergism; Electroenc

1997
Serotonin stimulation of calcium mobilisation in human platelets: choice of units of measurement, effects of age and tobacco use, and correlation with serotonin2A receptor density.
    Clinica chimica acta; international journal of clinical chemistry, 1999, Volume: 287, Issue:1-2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Amphetamines; Blood Platelets; Calcium; Female; H

1999
Behaviors induced by 5-hydroxytryptophan in neonatal, preweaning, postweaning, and adult Sprague-Dawley rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals,

1992
Serotonin receptor ontogeny: effects of agonists in 1-day-old rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 43, Issue:4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals, Newborn; Female; Indo

1992