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4-iodo-2,5-dimethoxyphenylisopropylamine and Action Tremor

4-iodo-2,5-dimethoxyphenylisopropylamine has been researched along with Action Tremor in 8 studies

4-iodo-2,5-dimethoxyphenylisopropylamine: RN given refers to unlabeled parent cpd without isomeric designation; a serotonin agonist
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine : An organoiodine compound that is amphetamine bearing two methoxy substituents at positions 2 and 5 as well as an iodo substituent at position 4.

Research Excerpts

ExcerptRelevanceReference
"We previously demonstrated that nicotine elicited kinetic tremor by elevating the neural activity of the inferior olive via α7 nicotinic acetylcholine (nACh) receptors."7.85Serotonergic modulation of nicotine-induced kinetic tremor in mice. ( Iha, HA; Kunisawa, N; Matsubara, N; Nomura, Y; Ohno, Y; Onishi, M; Shimizu, S, 2017)
"We previously demonstrated that nicotine elicited kinetic tremor by elevating the neural activity of the inferior olive via α7 nicotinic acetylcholine (nACh) receptors."3.85Serotonergic modulation of nicotine-induced kinetic tremor in mice. ( Iha, HA; Kunisawa, N; Matsubara, N; Nomura, Y; Ohno, Y; Onishi, M; Shimizu, S, 2017)
" The effect of chronic ACTH treatment on 5-HT(2) receptor and 5-HT(2A)-receptor mRNA levels was not altered by the chronic administration of imipramine."1.35Increased DOI-induced wet-dog shakes in adrenocorticotropic hormone-treated rats are not affected by chronic imipramine treatment: possible involvement of enhanced 5-HT(2A)-receptor expression in the frontal cortex. ( Akiyama, K; Fujitani, Y; Gomita, Y; Kanzaki, H; Kawasaki, H; Kimoto, S; Kitagawa, K; Kitamura, Y; Ouchida, M; Sendo, T; Shibata, K; Shimizu, K, 2008)
" (+/-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), a 5-HT2 receptor agonist, induced wet-dog shakes, but not hyperthermia and this response was increased 24 h after the chronic administration of CORT."1.30Effects of corticosterone on 5-HT1A and 5-HT2 receptor binding and on the receptor-mediated behavioral responses of rats. ( Kitamura, Y; Nagatani, T; Takao, K; Yamawaki, S, 1997)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (37.50)18.2507
2000's4 (50.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kunisawa, N1
Iha, HA1
Nomura, Y1
Onishi, M1
Matsubara, N1
Shimizu, S1
Ohno, Y1
Marek, GJ2
Kitamura, Y3
Kitagawa, K2
Fujitani, Y2
Shibata, K2
Araki, H1
Sendou, T1
Gomita, Y2
Zhang, C1
Akiyama, K1
Kimoto, S1
Kanzaki, H1
Ouchida, M1
Shimizu, K1
Kawasaki, H1
Sendo, T1
Baudrie, V1
De Vry, J1
Broqua, P1
Schmidt, B1
Chaouloff, F1
Glaser, T1
Takao, K1
Nagatani, T1
Yamawaki, S1
Mokler, DJ1
Sullivan, SA1
Winterson, BJ1

Other Studies

8 other studies available for 4-iodo-2,5-dimethoxyphenylisopropylamine and Action Tremor

ArticleYear
Serotonergic modulation of nicotine-induced kinetic tremor in mice.
    Journal of pharmacological sciences, 2017, Volume: 134, Issue:2

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Fenclonine; Humans; Male; Mice; Nicot

2017
Behavioral evidence for mu-opioid and 5-HT2A receptor interactions.
    European journal of pharmacology, 2003, Aug-01, Volume: 474, Issue:1

    Topics: Amphetamines; Animals; Behavior, Animal; Binding, Competitive; Buprenorphine; Cinnamates; Male; Morp

2003
The 5-HT1A receptor full agonist, 8-OH-DPAT inhibits ACTH-induced 5-HT2A receptor hyperfunction in rats: involvement of 5-HT1A receptors in the DOI-induced wet-dog shakes in ACTH-treated rats.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:1

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenocorticotropic Hormone; Amphetamines; Animals; Body Tem

2007
AMPA receptor involvement in 5-hydroxytryptamine2A receptor-mediated pre-frontal cortical excitatory synaptic currents and DOI-induced head shakes.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Jan-01, Volume: 32, Issue:1

    Topics: Amphetamines; Analysis of Variance; Animals; Behavior, Animal; Disease Models, Animal; Drug Interact

2008
Increased DOI-induced wet-dog shakes in adrenocorticotropic hormone-treated rats are not affected by chronic imipramine treatment: possible involvement of enhanced 5-HT(2A)-receptor expression in the frontal cortex.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:1

    Topics: Adrenocorticotropic Hormone; Amphetamines; Animals; Antidepressive Agents, Tricyclic; Binding Sites;

2008
Subchronic treatment with anxiolytic doses of the 5-HT1A receptor agonist ipsapirone does not affect 5-HT2 receptor sensitivity in the rat.
    European journal of pharmacology, 1993, Feb-16, Volume: 231, Issue:3

    Topics: Administration, Oral; Amphetamines; Animals; Anti-Anxiety Agents; Blood Glucose; Body Weight; Cortic

1993
Effects of corticosterone on 5-HT1A and 5-HT2 receptor binding and on the receptor-mediated behavioral responses of rats.
    European journal of pharmacology, 1997, Aug-27, Volume: 333, Issue:2-3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Anti-Inflammatory Agents; Behavior, A

1997
Behaviors induced by 5-hydroxytryptophan in neonatal, preweaning, postweaning, and adult Sprague-Dawley rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals,

1992