Page last updated: 2024-09-03

4-hydroxymephenytoin and Liver Dysfunction

4-hydroxymephenytoin has been researched along with Liver Dysfunction in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Branch, RA; Chaves-Gnecco, D; Frye, RF; Matzke, GR; Rabinovitz, M; Shaikh, OS; Zgheib, NK	1
Adedoyin, A; Arns, PA; Branch, RA; Richards, WO; Wilkinson, GR	1

Trials

2 trial(s) available for 4-hydroxymephenytoin and Liver Dysfunction

Article	Year
Liver disease selectively modulates cytochrome P450--mediated metabolism. Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3 Topics: Administration, Oral; Adult; Anticonvulsants; Antihypertensive Agents; Caffeine; Case-Control Studies; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Isoenzymes; Liver Diseases; Male; Mephenytoin; Middle Aged; Muscle Relaxants, Central; Phosphodiesterase Inhibitors; Severity of Illness Index; Theophylline	2006
Selective effect of liver disease on the activities of specific metabolizing enzymes: investigation of cytochromes P450 2C19 and 2D6. Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:1 Topics: Adult; Aged; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Humans; Liver Diseases; Male; Mephenytoin; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Stereoisomerism; Sympatholytics	1998

Article

Year

Liver disease selectively modulates cytochrome P450--mediated metabolism.

Clinical pharmacology and therapeutics, 2006, Volume: 80, Issue:3

Topics: Administration, Oral; Adult; Anticonvulsants; Antihypertensive Agents; Caffeine; Case-Control Studies; Chlorzoxazone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Debrisoquin; Humans; Isoenzymes; Liver Diseases; Male; Mephenytoin; Middle Aged; Muscle Relaxants, Central; Phosphodiesterase Inhibitors; Severity of Illness Index; Theophylline

2006

Selective effect of liver disease on the activities of specific metabolizing enzymes: investigation of cytochromes P450 2C19 and 2D6.

Clinical pharmacology and therapeutics, 1998, Volume: 64, Issue:1

Topics: Adult; Aged; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Cytochrome P-450 Enzyme System; Debrisoquin; Female; Humans; Liver Diseases; Male; Mephenytoin; Metabolic Clearance Rate; Middle Aged; Mixed Function Oxygenases; Stereoisomerism; Sympatholytics

1998