4-hydroxyderricin and Skin-Neoplasms

4-hydroxyderricin has been researched along with Skin-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 4-hydroxyderricin and Skin-Neoplasms

Article	Year
The Ashitaba ( Cancer prevention research (Philadelphia, Pa.), 2018, Volume: 11, Issue:10 Malignant melanoma is an aggressive tumor of the skin and still lacks effective preventive and therapeutic treatments. In melanoma, both the BRAF/MEK/ERK and PI3-K/AKT signaling pathways are constitutively activated through multiple mechanisms, which result in cell-cycle progression and prevention of apoptosis. Therefore, the development of novel strategies for targeting BRAF and PI3K are of utmost importance. In this study, we found that Ashitaba ( Topics: Angelica; Animals; Carcinogenesis; Cell Line, Tumor; Chalcone; Drug Screening Assays, Antitumor; Humans; Melanoma, Experimental; Mice; Mice, Knockout; Mutation; Phosphatidylinositol 3-Kinases; Plant Extracts; Proto-Oncogene Proteins B-raf; PTEN Phosphohydrolase; Signal Transduction; Skin Neoplasms; Treatment Outcome	2018

Article

Year

Cancer prevention research (Philadelphia, Pa.), 2018, Volume: 11, Issue:10

Malignant melanoma is an aggressive tumor of the skin and still lacks effective preventive and therapeutic treatments. In melanoma, both the BRAF/MEK/ERK and PI3-K/AKT signaling pathways are constitutively activated through multiple mechanisms, which result in cell-cycle progression and prevention of apoptosis. Therefore, the development of novel strategies for targeting BRAF and PI3K are of utmost importance. In this study, we found that Ashitaba (

Topics: Angelica; Animals; Carcinogenesis; Cell Line, Tumor; Chalcone; Drug Screening Assays, Antitumor; Humans; Melanoma, Experimental; Mice; Mice, Knockout; Mutation; Phosphatidylinositol 3-Kinases; Plant Extracts; Proto-Oncogene Proteins B-raf; PTEN Phosphohydrolase; Signal Transduction; Skin Neoplasms; Treatment Outcome

2018