Page last updated: 2024-08-26

4-hydroxycyclophosphamide and Neoplasms, Germ Cell and Embryonal

4-hydroxycyclophosphamide has been researched along with Neoplasms, Germ Cell and Embryonal in 2 studies

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Beijnen, JH; de Jonge, ME; Huitema, AD; Rodenhuis, S; van Dam, SM	1
Beijnen, JH; Doodeman, VD; Ekhart, C; Huitema, AD; Rodenhuis, S; Smits, PH	1

Trials

1 trial(s) available for 4-hydroxycyclophosphamide and Neoplasms, Germ Cell and Embryonal

Article	Year
Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin. Therapeutic drug monitoring, 2005, Volume: 27, Issue:6 Topics: Adolescent; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Carboplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Models, Biological; Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Phosphoramide Mustards; Prodrugs; Thiotepa; Time Factors; Triethylenephosphoramide	2005

Article

Year

Population pharmacokinetics of cyclophosphamide and its metabolites 4-hydroxycyclophosphamide, 2-dechloroethylcyclophosphamide, and phosphoramide mustard in a high-dose combination with Thiotepa and Carboplatin.

Therapeutic drug monitoring, 2005, Volume: 27, Issue:6

Topics: Adolescent; Adult; Algorithms; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Breast Neoplasms; Carboplatin; Cyclophosphamide; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Half-Life; Humans; Infusions, Intravenous; Male; Middle Aged; Models, Biological; Neoplasms; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Phosphoramide Mustards; Prodrugs; Thiotepa; Time Factors; Triethylenephosphoramide

2005

Other Studies

1 other study(ies) available for 4-hydroxycyclophosphamide and Neoplasms, Germ Cell and Embryonal

Article	Year
Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide. Pharmacogenetics and genomics, 2008, Volume: 18, Issue:6 Topics: Adolescent; Adult; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aryl Hydrocarbon Hydroxylases; Base Sequence; Breast Neoplasms; Cohort Studies; Cyclophosphamide; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Primers; Female; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Male; Middle Aged; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Oxidoreductases, N-Demethylating; Pharmacogenetics; Polymorphism, Genetic; Retinal Dehydrogenase	2008

Article

Year

Influence of polymorphisms of drug metabolizing enzymes (CYP2B6, CYP2C9, CYP2C19, CYP3A4, CYP3A5, GSTA1, GSTP1, ALDH1A1 and ALDH3A1) on the pharmacokinetics of cyclophosphamide and 4-hydroxycyclophosphamide.

Pharmacogenetics and genomics, 2008, Volume: 18, Issue:6

Topics: Adolescent; Adult; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aryl Hydrocarbon Hydroxylases; Base Sequence; Breast Neoplasms; Cohort Studies; Cyclophosphamide; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; DNA Primers; Female; Glutathione S-Transferase pi; Glutathione Transferase; Humans; Male; Middle Aged; Neoplasms, Germ Cell and Embryonal; Ovarian Neoplasms; Oxidoreductases, N-Demethylating; Pharmacogenetics; Polymorphism, Genetic; Retinal Dehydrogenase

2008