4-hydroxybutyric acid has been researched along with Substance Withdrawal Syndrome in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (3.70) | 18.2507 |
| 2000's | 13 (48.15) | 29.6817 |
| 2010's | 7 (25.93) | 24.3611 |
| 2020's | 6 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Brunetti, P; Umani Ronchi, F | 1 |
| Ebdrup, BH; Kjærgaard, MF; Nørbæk, JJ; Videbech, P | 1 |
| Bae, JW; Choi, B; Ji, M; Kim, M; Kim, S; Lee, S; Lee, YS; Oh, S; Paik, MJ | 1 |
| Kestens, C; Moitroux, A | 1 |
| Dijkstra, B; van Mechelen, JC; Vergouwen, A | 1 |
| Beurmanjer, H; Buwalda, VJA; De Jong, CAJ; De Wilde, B; Dijkstra, BAG; Luykx, JJ; Schellekens, AFA; van Rompaey, K | 1 |
| Amsterdam, JV; Brink, WVD; Brunt, TM; Crunelle, CL; Pereira, FR | 1 |
| Broers, B; de Jong, CA; Kamal, R; van Noorden, M | 1 |
| de Jong, CA; Dijkstra, BA; Kamal, RM; van Iwaarden, S | 1 |
| Boettger, S; Claussen, MC; Hassanpour, K; Jenewein, J | 1 |
| Greene, S; Kailainathan, R; Koutsogiannis, Z; Wong, A | 1 |
| Elsing, C; Grenda, U; Herrmann, T; Stremmel, W | 1 |
| Bernardi, M; Caputo, F; Maremmani, I; Vignoli, T; Zoli, G | 1 |
| Amato, L; Davoli, M; Minozzi, S | 1 |
| Dell'Osso, L; Maremmani, AG; Maremmani, I; Pacini, M; Pani, PP; Rovai, L | 1 |
| Biggio, F; Biggio, G; Busonero, F; Follesa, P; Manca, A; Mancuso, L; Mascia, MP; Mostallino, MC; Sanna, E; Talani, G | 1 |
| Atzeri, S; Carai, MA; Colombo, G; Gessa, GL; Lobina, C; Maccioni, P; Maher, TJ; Orrù, A; Quang, LS | 1 |
| Gibson, KM; Snead, OC | 1 |
| Gortner, L; Gottschling, S; Kleinschmidt, S; Meyer, S; Strittmatter, M | 1 |
| Addolorato, G; Gasbarrini, G | 1 |
| Carai, MA; Colombo, G; Gessa, GL; Lobina, C; Maccioni, P; Maher, TJ; Orru, A; Quang, LS | 1 |
| Bernardi, M; Caputo, F; Francini, S; Stoppo, M; Vignoli, T | 1 |
| Bennett, WR; Roy-Byrne, PP; Wilson, LG | 1 |
| Addolorato, G; Attilia, ML; Balducci, G; Capristo, E; Ceccanti, M; Gasbarrini, G; Taggi, F | 1 |
| Gallimberti, L; Gessa, GL; Soncini, CA; Spella, MR | 1 |
| Contini, SE; Frederick-Osborne, SL; Galloway, GP; Seymour, R; Smith, DE | 1 |
| Agabio, R; Carai, MA; Colombo, G; Gessa, GL; Lobina, C; Pani, M; Reali, R | 1 |
8 review(s) available for 4-hydroxybutyric acid and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Cognitive Impairment Following Clinical or Recreational Use of Gammahydroxybutyric Acid (GHB): A Systematic Review.
Topics: Alcoholism; Animals; Cognitive Dysfunction; Coma; Humans; Hydroxybutyrates; Illicit Drugs; Neurotoxicity Syndromes; Sodium Oxybate; Substance Withdrawal Syndrome | 2022 |
Gamma hydroxybutyric acid (GHB) for the treatment of alcohol dependence: a review.
Topics: Alcoholism; Humans; Hydroxybutyrates; Motivation; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome | 2009 |
Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome.
Topics: Alcohol Withdrawal Seizures; Alcoholism; Anticonvulsants; Baclofen; Benzodiazepines; Ethanol; Humans; Hydroxybutyrates; Nitrous Oxide; Substance Withdrawal Syndrome | 2011 |
Gamma-hydroxybutyric acid.
Topics: 4-Butyrolactone; Animals; Butylene Glycols; Humans; Hydroxybutyrates; Receptors, Cell Surface; Receptors, Dopamine; Receptors, GABA; Substance Withdrawal Syndrome; Substance-Related Disorders | 2005 |
[Gamma-hydroxy butyric acid: neurotransmitter, sedative and party drug].
Topics: Adult; Animals; Brain; Child; Critical Care; Drug Overdose; gamma-Aminobutyric Acid; Humans; Hydroxybutyrates; Hypnotics and Sedatives; Illicit Drugs; Neurotransmitter Agents; Substance Withdrawal Syndrome | 2005 |
Gamma-hydroxybutyric acid in the treatment of alcohol and heroin dependence.
Topics: Alcoholism; Clinical Trials as Topic; Heroin Dependence; Humans; Hydroxybutyrates; Substance Withdrawal Syndrome; Substance-Related Disorders | 2000 |
Abuse and therapeutic potential of gamma-hydroxybutyric acid.
Topics: Alcoholism; Animals; Brain; Humans; Hydroxybutyrates; Substance Withdrawal Syndrome; Substance-Related Disorders | 2000 |
Mechanism of the antialcohol effect of gamma-hydroxybutyric acid.
Topics: Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Humans; Hydroxybutyrates; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 2000 |
2 trial(s) available for 4-hydroxybutyric acid and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Gamma-hydroxybutyric acid versus clomethiazole for the treatment of alcohol withdrawal syndrome in a medical intensive care unit: an open, single-center randomized study.
Topics: Adult; Alcoholism; Chlormethiazole; Comorbidity; Female; GABA Modulators; Humans; Hydroxybutyrates; Intensive Care Units; Length of Stay; Male; Middle Aged; Severity of Illness Index; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome | 2009 |
Gamma-hydroxybutyric acid (GHB) in the treatment of alcohol withdrawal syndrome: a randomized comparative study versus benzodiazepine.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Central Nervous System Depressants; Depression; Ethanol; Female; Humans; Hydroxybutyrates; Male; Middle Aged; Substance Withdrawal Syndrome; Surveys and Questionnaires | 1999 |
17 other study(ies) available for 4-hydroxybutyric acid and Substance Withdrawal Syndrome
| Article | Year |
|---|---|
Recreational use of GHB and prescribed drugs: the challenge in forensic and clinical toxicology.
Topics: Humans; Hydroxybutyrates; Illicit Drugs; Sodium Oxybate; Substance Withdrawal Syndrome | 2021 |
Gamma-hydroxybutyric acid-induced organic delirium complicated by polydrug use successfully treated with electroconvulsive therapy: a case report.
Topics: Adult; Delirium; Electroconvulsive Therapy; Humans; Hydroxybutyrates; Male; Substance Withdrawal Syndrome; Young Adult | 2021 |
Alcohol perturbed locomotor behavior, metabolism, and pharmacokinetics of gamma-hydroxybutyric acid in rats.
Topics: Alcoholism; Animals; Ethanol; gamma-Aminobutyric Acid; Rats; Sodium Oxybate; Substance Withdrawal Syndrome | 2023 |
[Withdrawal syndrome following chronic use of gamma-hydroxybutyric acid (GHB)].
Topics: Benzodiazepines; Humans; Hydroxybutyrates; Sodium Oxybate; Substance Withdrawal Syndrome | 2023 |
Severe illicit gamma-hydroxybutyric acid withdrawal in a pregnant woman: what to do?
Topics: Adult; Female; Humans; Hydroxybutyrates; Illicit Drugs; Pregnancy; Pregnancy Complications; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders | 2019 |
Tapering with Pharmaceutical GHB or Benzodiazepines for Detoxification in GHB-Dependent Patients: A Matched-Subject Observational Study of Treatment-as-Usual in Belgium and The Netherlands.
Topics: Adult; Belgium; Benzodiazepines; Craving; Drug Tapering; Female; Humans; Hydroxybutyrates; Male; Netherlands; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult | 2020 |
Treatment of GHB withdrawal syndrome: Catch 22 or challenge for addiction medicine?
Topics: Humans; Hydroxybutyrates; Practice Guidelines as Topic; Substance Withdrawal Syndrome | 2013 |
Decision rules for GHB (γ-hydroxybutyric acid) detoxification: a vignette study.
Topics: Adult; Behavior, Addictive; Cohort Studies; Decision Making; Female; Humans; Hydroxybutyrates; Male; Prospective Studies; Psychiatry; Substance Abuse Treatment Centers; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult | 2014 |
Catatonic stupor secondary to gamma-hydroxy-butyric acid (GHB)-dependence and -withdrawal syndrome.
Topics: Catatonia; Humans; Hydroxybutyrates; Male; Middle Aged; Stupor; Substance Withdrawal Syndrome; Substance-Related Disorders | 2014 |
Recognition of gamma-hydroxybutyric acid withdrawal: Rapid progression and prolonged symptomatology.
Topics: Adult; Anti-Bacterial Agents; Australia; Baclofen; Benzodiazepines; Diazepam; Humans; Hydroxybutyrates; Male; Penicillanic Acid; Phenobarbital; Piperacillin; Pneumonia; Psychomotor Agitation; Substance Withdrawal Syndrome; Sweating; Tazobactam; Tremor | 2017 |
Long-term γ-hydroxybutyric acid (GHB) and disulfiram combination therapy in GHB treatment-resistant chronic alcoholics.
Topics: Adult; Alcohol Deterrents; Alcoholics; Alcoholism; Disulfiram; Drug Therapy, Combination; Ethanol; Female; Humans; Hydroxybutyrates; Italy; Male; Retrospective Studies; Substance Withdrawal Syndrome; Treatment Outcome | 2011 |
Gamma-hydroxybutyric acid and diazepam antagonize a rapid increase in GABA(A) receptors alpha(4) subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells.
Topics: Animals; Cells, Cultured; Cerebellum; Diazepam; Drug Interactions; Electrophysiology; Ethanol; Humans; Hydroxybutyrates; Neurons; Protein Subunits; Rats; Receptors, GABA-A; RNA, Messenger; Substance Withdrawal Syndrome; Transfection; Xenopus laevis | 2003 |
Withdrawal syndrome from gamma-hydroxybutyric acid (GHB) and 1,4-butanediol (1,4-BD) in Sardinian alcohol-preferring rats.
Topics: Animals; Butylene Glycols; Disease Models, Animal; GABA-B Receptor Antagonists; Hydroxybutyrates; Male; Morpholines; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 2005 |
Gamma-hydroxybutyric acid.
Topics: Alcoholism; Humans; Hydroxybutyrates; Substance Withdrawal Syndrome | 2005 |
Evaluation for the withdrawal syndrome from gamma-hydroxybutyric acid (GHB), gamma-butyrolactone (GBL), and 1,4-butanediol (1,4-BD) in different rat lines.
Topics: 4-Butyrolactone; Animals; Behavior, Animal; Butylene Glycols; Female; Hydroxybutyrates; Rats; Rats, Inbred Strains; Rats, Sprague-Dawley; Rats, Wistar; Seizures; Substance Withdrawal Syndrome | 2006 |
GABAergic medications for treating alcohol dependence.
Topics: Alcoholism; Baclofen; Drug Therapy, Combination; GABA Agonists; gamma-Aminobutyric Acid; Humans; Hydroxybutyrates; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Receptors, GABA-B; Substance Withdrawal Syndrome; Temperance | 2007 |
Gamma-hydroxybutyric acid (GHB) withdrawal: a case report.
Topics: Adjuvants, Anesthesia; Adult; Antipsychotic Agents; Benzodiazepines; Humans; Hydroxybutyrates; Male; Olanzapine; Substance Withdrawal Syndrome; Treatment Failure | 2007 |