4-hydroxybutyric acid has been researched along with Alcoholism in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (7.14) | 18.2507 |
| 2000's | 20 (71.43) | 29.6817 |
| 2010's | 4 (14.29) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Bae, JW; Choi, B; Ji, M; Kim, M; Kim, S; Lee, S; Lee, YS; Oh, S; Paik, MJ | 1 |
| Amsterdam, JV; Brink, WVD; Brunt, TM; Crunelle, CL; Pereira, FR | 1 |
| Griffiths, RR; Johnson, MW | 1 |
| Addolorato, G; Bernardi, M; Caputo, F; Comaschi, C; Del Re, A; Francini, S; Leggio, L; Lorenzini, F; Stoppo, M; Vignoli, T; Zoli, G | 1 |
| Castelli, MP | 1 |
| Benarroch, EE | 1 |
| Elsing, C; Grenda, U; Herrmann, T; Stremmel, W | 1 |
| Bernardi, M; Caputo, F; Maremmani, I; Vignoli, T; Zoli, G | 1 |
| Briani, C; Cagnin, A; Dam, M; Manfioli, V; Pompanin, S; Saladini, M; Zambon, A | 1 |
| Amato, L; Davoli, M; Minozzi, S | 1 |
| Dell'Osso, L; Maremmani, AG; Maremmani, I; Pacini, M; Pani, PP; Rovai, L | 1 |
| Addolorato, G; Bernardi, M; Caputo, F; del RE, A; Domenicali, M; Gasbarrini, G; Greco, G; Lorenzini, F; Stefanini, GF | 1 |
| Addolorato, G; Gasbarrini, G | 1 |
| Eichhorn, M; Hardmeier, M; Stoppe, G | 1 |
| Bernardi, M; Caputo, F | 1 |
| Bernardi, M; Caputo, F; Francini, S; Stoppo, M; Vignoli, T | 1 |
| Carai, MA; Colombo, G; Fantini, N; Gessa, GL; Maccioni, P; Pes, D | 1 |
| Addolorato, G; Berrino, L; Capuano, A; Maione, S; Rinaldi, B; Rossi, F; Stella, L | 1 |
| Addolorato, G; Capristo, E; Caputo, F; Gasbarrini, G; Gessa, GL; Stefanini, GF | 1 |
| Addolorato, G; Capristo, E; Caputo, F; Gasbarrini, G; Stefanini, GF | 1 |
| Beghè, F; Carpanini, MT | 1 |
| Gallimberti, L; Gessa, GL; Soncini, CA; Spella, MR | 1 |
| Contini, SE; Frederick-Osborne, SL; Galloway, GP; Seymour, R; Smith, DE | 1 |
| Agabio, R; Carai, MA; Colombo, G; Gessa, GL; Lobina, C; Pani, M; Reali, R | 1 |
| Gambassi, F; Mannaioni, PF; Masini, E; Moncini, M | 1 |
| Addolorato, G; Capristo, E; Caputo, F; Cibin, M; Gasbarrini, G; Gessa, GL; Stefanini, GF | 1 |
| Coiro, V; Vescovi, PP | 1 |
9 review(s) available for 4-hydroxybutyric acid and Alcoholism
| Article | Year |
|---|---|
Cognitive Impairment Following Clinical or Recreational Use of Gammahydroxybutyric Acid (GHB): A Systematic Review.
Topics: Alcoholism; Animals; Cognitive Dysfunction; Coma; Humans; Hydroxybutyrates; Illicit Drugs; Neurotoxicity Syndromes; Sodium Oxybate; Substance Withdrawal Syndrome | 2022 |
Multi-faceted aspects of gamma-hydroxybutyric acid: a neurotransmitter, therapeutic agent and drug of abuse.
Topics: Alcoholism; Anesthesia; Animals; Binding Sites; Blood-Brain Barrier; Brain; Electrophysiology; Haplorhini; Humans; Hydroxybutyrates; Hypnosis; Ligands; Models, Chemical; Neurotransmitter Agents; Signal Transduction | 2008 |
Gamma hydroxybutyric acid (GHB) for the treatment of alcohol dependence: a review.
Topics: Alcoholism; Humans; Hydroxybutyrates; Motivation; Randomized Controlled Trials as Topic; Substance Withdrawal Syndrome | 2009 |
Efficacy and safety of pharmacological interventions for the treatment of the Alcohol Withdrawal Syndrome.
Topics: Alcohol Withdrawal Seizures; Alcoholism; Anticonvulsants; Baclofen; Benzodiazepines; Ethanol; Humans; Hydroxybutyrates; Nitrous Oxide; Substance Withdrawal Syndrome | 2011 |
Gamma-hydroxybutyric acid efficacy, potential abuse, and dependence in the treatment of alcohol addiction.
Topics: Alcoholism; Humans; Hydroxybutyrates; Substance-Related Disorders; Treatment Outcome | 2000 |
Safety and tolerability of gamma-hydroxybutyric acid in the treatment of alcohol-dependent patients.
Topics: Alcoholism; Humans; Hydroxybutyrates; Substance-Related Disorders | 2000 |
Gamma-hydroxybutyric acid in the treatment of alcohol and heroin dependence.
Topics: Alcoholism; Clinical Trials as Topic; Heroin Dependence; Humans; Hydroxybutyrates; Substance Withdrawal Syndrome; Substance-Related Disorders | 2000 |
Abuse and therapeutic potential of gamma-hydroxybutyric acid.
Topics: Alcoholism; Animals; Brain; Humans; Hydroxybutyrates; Substance Withdrawal Syndrome; Substance-Related Disorders | 2000 |
Mechanism of the antialcohol effect of gamma-hydroxybutyric acid.
Topics: Alcohol Drinking; Alcoholism; Animals; Dopamine; Ethanol; Humans; Hydroxybutyrates; Rats; Substance Withdrawal Syndrome; Substance-Related Disorders | 2000 |
4 trial(s) available for 4-hydroxybutyric acid and Alcoholism
| Article | Year |
|---|---|
Gamma-hydroxybutyric acid versus clomethiazole for the treatment of alcohol withdrawal syndrome in a medical intensive care unit: an open, single-center randomized study.
Topics: Adult; Alcoholism; Chlormethiazole; Comorbidity; Female; GABA Modulators; Humans; Hydroxybutyrates; Intensive Care Units; Length of Stay; Male; Middle Aged; Severity of Illness Index; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome | 2009 |
Gamma-hydroxybutyric acid versus naltrexone in maintaining alcohol abstinence: an open randomized comparative study.
Topics: Alcohol Drinking; Alcoholism; Female; Humans; Hydroxybutyrates; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Temperance; Time Factors; Treatment Outcome | 2003 |
An open randomized study of the treatment of escitalopram alone and combined with gamma-hydroxybutyric acid and naltrexone in alcoholic patients.
Topics: Adult; Alcoholism; Citalopram; Drug Therapy, Combination; Female; Humans; Hydroxybutyrates; Male; Middle Aged; Naltrexone; Narcotic Antagonists; Selective Serotonin Reuptake Inhibitors | 2008 |
Gamma-hydroxybutyric acid and alcohol-related syndromes.
Topics: Adolescent; Adult; Aged; Alcohol Withdrawal Delirium; Alcohol-Related Disorders; Alcoholism; Double-Blind Method; Female; Humans; Hydroxybutyrates; Male; Middle Aged; Placebos; Recurrence | 2000 |
15 other study(ies) available for 4-hydroxybutyric acid and Alcoholism
| Article | Year |
|---|---|
Alcohol perturbed locomotor behavior, metabolism, and pharmacokinetics of gamma-hydroxybutyric acid in rats.
Topics: Alcoholism; Animals; Ethanol; gamma-Aminobutyric Acid; Rats; Sodium Oxybate; Substance Withdrawal Syndrome | 2023 |
Comparative abuse liability of GHB and ethanol in humans.
Topics: Alcoholism; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hydroxybutyrates; Male; Placebos; Psychomotor Performance | 2013 |
Incidence of craving for and abuse of gamma-hydroxybutyric acid (GHB) in different populations of treated alcoholics: an open comparative study.
Topics: Adult; Alcoholics; Alcoholism; Female; Humans; Hydroxybutyrates; Male; Middle Aged; Substance-Related Disorders | 2009 |
Gamma-hydroxybutyric acid and its relevance in neurology.
Topics: Alcoholism; Brain; Humans; Hydroxybutyrates; Narcolepsy; Nervous System Diseases; Neurology; Neuroprotective Agents; Substance-Related Disorders; Succinate-Semialdehyde Dehydrogenase | 2009 |
γ-Hydroxybutyric acid-induced psychosis and seizures.
Topics: Alcoholism; Bipolar Disorder; Electroencephalography; Female; Humans; Hydroxybutyrates; Middle Aged; Psychoses, Substance-Induced; Seizures | 2011 |
Long-term γ-hydroxybutyric acid (GHB) and disulfiram combination therapy in GHB treatment-resistant chronic alcoholics.
Topics: Adult; Alcohol Deterrents; Alcoholics; Alcoholism; Disulfiram; Drug Therapy, Combination; Ethanol; Female; Humans; Hydroxybutyrates; Italy; Male; Retrospective Studies; Substance Withdrawal Syndrome; Treatment Outcome | 2011 |
Gamma-hydroxybutyric acid.
Topics: Alcoholism; Humans; Hydroxybutyrates; Substance Withdrawal Syndrome | 2005 |
[Agitation and gamma-hydroxybutyrate].
Topics: Akathisia, Drug-Induced; Alcoholism; Commitment of Mentally Ill; Comorbidity; Diagnosis, Differential; Humans; Hydroxybutyrates; Life Change Events; Male; Middle Aged; Recurrence; Substance Abuse Detection; Substance-Related Disorders; Video Recording | 2006 |
Treatment of alcohol dependence with gamma hydroxybutyric acid.
Topics: Alcoholism; Humans; Hydroxybutyrates; Substance-Related Disorders | 2007 |
GABAergic medications for treating alcohol dependence.
Topics: Alcoholism; Baclofen; Drug Therapy, Combination; GABA Agonists; gamma-Aminobutyric Acid; Humans; Hydroxybutyrates; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Receptors, GABA-B; Substance Withdrawal Syndrome; Temperance | 2007 |
gamma-Hydroxybutyric acid (GHB) suppresses alcohol's motivational properties in alcohol-preferring rats.
Topics: Alcohol Drinking; Alcoholism; Animals; Conditioning, Operant; Dose-Response Relationship, Drug; Extinction, Psychological; Hydroxybutyrates; Male; Motivation; Rats; Receptors, GABA-B; Self Administration | 2008 |
Long-term administration of GHB does not affect muscular mass in alcoholics.
Topics: Adult; Alcoholism; Body Composition; Case-Control Studies; Human Growth Hormone; Humans; Hydroxybutyrates; Male; Muscles; Time Factors; Treatment Outcome | 1999 |
Gamma-hydroxybutyric acid in the treatment of alcoholism: dosage fractioning utility in non-responder alcoholic patients.
Topics: Adult; Alcoholism; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hydroxybutyrates; Male; Middle Aged; Temperance; Treatment Outcome | 1998 |
Gamma-hydroxybutyric acid: a neurotransmitter, a medicine, a drug of abuse. Proceedings of the 8th Congress of the Italian Society on Biological Psychiatry. Naples, Italy, September 29-October 3, 1998.
Topics: Alcoholism; Animals; Humans; Hydroxybutyrates; Neurotransmitter Agents; Substance-Related Disorders | 2000 |
Different control of GH secretion by gamma-amino- and gamma-hydroxy-butyric acid in 4-year abstinent alcoholics.
Topics: Adult; Alcoholism; Baclofen; Biomarkers; GABA Agents; GABA Agonists; gamma-Aminobutyric Acid; Growth Hormone; Humans; Hydroxybutyrates; Male; Statistics, Nonparametric; Temperance; Valproic Acid | 2001 |