4-hydroxybenzyl alcohol has been researched along with Disease Models, Animal in 4 studies
4-hydroxybenzyl alcohol: the aglycone of gastrodin
p-hydroxybenzyl alcohol : A member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pharmacokinetic assessment of TMP, FA, gastrodin or gastrodigenin in blood or brain interstitial fluid (BIF) has been reported in healthy animals." | 1.56 | Pharmacokinetic comparative study of tetramethylpyrazine and ferulic acid and their compatibility with different concentration of gastrodin and gastrodigenin on blood-stasis migraine model by blood-brain microdialysis method. ( Cheng, H; Guo, S; Ke, G; Liu, M; Mao, Y; Mi, Y; Wang, M; Wei, P, 2020) |
| "HBA treatment prevented the memory deficits of the AD mice." | 1.51 | p-Hydroxybenzyl Alcohol Prevents Memory Deficits by Increasing Neurotrophic Factors and Decreasing Inflammatory Factors in a Mice Model of Alzheimer's Disease. ( Bao, X; Ding, Y; Lao, L; Ling, Y; Wang, Q; Xu, S, 2019) |
| "Ischemic injury was induced for 1 h by middle cerebral artery occlusion (MCAO) followed by 24-h reperfusion." | 1.37 | p-Hydroxybenzyl alcohol prevents brain injury and behavioral impairment by activating Nrf2, PDI, and neurotrophic factor genes in a rat model of brain ischemia. ( Choi, YW; Hong, JH; Jalin, AM; Jeong, N; Kam, KY; Kang, SG; Lee, CK; Lee, S; Yu, SJ, 2011) |
| "The therapeutic goal in treating cerebral ischemia is to reduce the extent of brain injury and thus minimize neurological impairment." | 1.37 | p-Hydroxybenzyl alcohol prevents brain injury and behavioral impairment by activating Nrf2, PDI, and neurotrophic factor genes in a rat model of brain ischemia. ( Choi, YW; Hong, JH; Jalin, AM; Jeong, N; Kam, KY; Kang, SG; Lee, CK; Lee, S; Yu, SJ, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mi, Y | 1 |
| Guo, S | 1 |
| Cheng, H | 1 |
| Liu, M | 1 |
| Wei, P | 1 |
| Wang, M | 1 |
| Mao, Y | 1 |
| Ke, G | 1 |
| Ding, Y | 1 |
| Bao, X | 1 |
| Lao, L | 1 |
| Ling, Y | 1 |
| Wang, Q | 1 |
| Xu, S | 1 |
| Cho, BR | 1 |
| Ryu, DR | 1 |
| Lee, KS | 1 |
| Lee, DK | 1 |
| Bae, S | 1 |
| Kang, DG | 1 |
| Ke, Q | 1 |
| Singh, SS | 1 |
| Ha, KS | 1 |
| Kwon, YG | 1 |
| Lee, D | 1 |
| Kang, PM | 1 |
| Kim, YM | 1 |
| Kam, KY | 1 |
| Yu, SJ | 1 |
| Jeong, N | 1 |
| Hong, JH | 1 |
| Jalin, AM | 1 |
| Lee, S | 1 |
| Choi, YW | 1 |
| Lee, CK | 1 |
| Kang, SG | 1 |
4 other studies available for 4-hydroxybenzyl alcohol and Disease Models, Animal