4-hydroxybenzyl alcohol has been researched along with Brain Ischemia in 4 studies
4-hydroxybenzyl alcohol: the aglycone of gastrodin
p-hydroxybenzyl alcohol : A member of the class of benzyl alcohols that is benzyl alcohol substituted by a hydroxy group at position 4. It has been isolated from Arcangelisia gusanlung.
Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A rat model of middle cerebral artery occlusion and reperfusion (MCAO/R) was used in the present study." | 1.91 | P‑hydroxybenzyl alcohol ameliorates neuronal cerebral ischemia‑reperfusion injury by activating mitochondrial autophagy through SIRT1. ( Chen, P; Duan, X; Luo, Y; Yang, L; Yu, X, 2023) |
| "Ischemic injury was induced for 1 h by middle cerebral artery occlusion (MCAO) followed by 24-h reperfusion." | 1.37 | p-Hydroxybenzyl alcohol prevents brain injury and behavioral impairment by activating Nrf2, PDI, and neurotrophic factor genes in a rat model of brain ischemia. ( Choi, YW; Hong, JH; Jalin, AM; Jeong, N; Kam, KY; Kang, SG; Lee, CK; Lee, S; Yu, SJ, 2011) |
| "The therapeutic goal in treating cerebral ischemia is to reduce the extent of brain injury and thus minimize neurological impairment." | 1.37 | p-Hydroxybenzyl alcohol prevents brain injury and behavioral impairment by activating Nrf2, PDI, and neurotrophic factor genes in a rat model of brain ischemia. ( Choi, YW; Hong, JH; Jalin, AM; Jeong, N; Kam, KY; Kang, SG; Lee, CK; Lee, S; Yu, SJ, 2011) |
| "Vanillin and 4-HBA treatment blocked oxidative damage in PC12 cells." | 1.34 | Vanillin, 4-hydroxybenzyl aldehyde and 4-hydroxybenzyl alcohol prevent hippocampal CA1 cell death following global ischemia. ( Hwang, IK; Kim, HJ; Won, MH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, X | 1 |
| Luo, Y | 1 |
| Yang, L | 1 |
| Chen, P | 1 |
| Duan, X | 1 |
| Kam, KY | 1 |
| Yu, SJ | 2 |
| Jeong, N | 1 |
| Hong, JH | 2 |
| Jalin, AM | 1 |
| Lee, S | 1 |
| Choi, YW | 1 |
| Lee, CK | 2 |
| Kang, SG | 2 |
| Kim, JR | 1 |
| Han, JE | 1 |
| Lee, JH | 1 |
| Kim, HS | 1 |
| Kim, HJ | 1 |
| Hwang, IK | 1 |
| Won, MH | 1 |
4 other studies available for 4-hydroxybenzyl alcohol and Brain Ischemia
| Article | Year |
|---|---|
P‑hydroxybenzyl alcohol ameliorates neuronal cerebral ischemia‑reperfusion injury by activating mitochondrial autophagy through SIRT1.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Brain Ischemia | 2023 |
p-Hydroxybenzyl alcohol prevents brain injury and behavioral impairment by activating Nrf2, PDI, and neurotrophic factor genes in a rat model of brain ischemia.
Topics: Animals; Bacitracin; Behavior, Animal; Benzyl Alcohols; Brain Injuries; Brain Ischemia; Cell Death; | 2011 |
Gastrodia elata blume and an active component, p-hydroxybenzyl alcohol reduce focal ischemic brain injury through antioxidant related gene expressions.
Topics: Animals; Antioxidants; Benzyl Alcohols; Brain Ischemia; Gastrodia; Gene Expression Regulation; Male; | 2005 |
Vanillin, 4-hydroxybenzyl aldehyde and 4-hydroxybenzyl alcohol prevent hippocampal CA1 cell death following global ischemia.
Topics: Animals; Benzaldehydes; Benzyl Alcohols; Brain Ischemia; Cell Death; Female; Gastrodia; Gerbillinae; | 2007 |