Compounds > 4-hydroxy-equilenin
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4-hydroxy-equilenin and Breast Neoplasms

4-hydroxy-equilenin has been researched along with Breast Neoplasms in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (85.71)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bolton, JL; Edirisinghe, P; Geacintov, NE; Qin, Z; Sohn, J; Thatcher, GR; Wang, Z1
Blond, SY; Bolton, JL; Chang, M; Elguindi, EC; Li, Y; Liu, X; Pisha, E; Yao, D; Yao, J1
Bolton, JL; Chang, M; Li, Y; Mesecar, AD; Nikolic, D; van Breemen, RB; Yager, JD; Yao, J; Yu, L1
Bolton, JL; Li, Y; van Breemen, RB; Yang, X1
Blond, SY; Bolton, JL; Chen, Y; Constantinou, AI; Elguindi, EC; Hua, Y; Liu, X; Pisha, E; Shen, L; van Breemen, RB; Zhang, F1
Bolton, JL; Hua, Y; Liu, X; Pisha, E; van Breemen, RB; Yang, Y; Yao, J1

Other Studies

7 other study(ies) available for 4-hydroxy-equilenin and Breast Neoplasms

ArticleYear
Development of a liquid chromatography electrospray ionization tandem mass spectrometry method for analysis of stable 4-hydroxyequilenin-DNA adducts in human breast cancer cells.
    Chemical research in toxicology, 2009, Volume: 22, Issue:6

    Topics: Animals; Breast Neoplasms; Chromatography, High Pressure Liquid; DNA Adducts; DNA Damage; Equilenin; Female; Humans; Hydrogen-Ion Concentration; Oxidation-Reduction; Spectrometry, Mass, Electrospray Ionization; Stereoisomerism; Swine; Tandem Mass Spectrometry; Temperature; Tumor Cells, Cultured

2009
In this issue. Estrogen double whammy.
    Chemical research in toxicology, 2010, Aug-16, Volume: 23, Issue:8

    Topics: Animals; Breast Neoplasms; DNA Damage; Equilenin; Estrogen Replacement Therapy; Horses; Humans; Mice; Oligonucleotides; Reactive Oxygen Species

2010
Inhibition of cellular enzymes by equine catechol estrogens in human breast cancer cells: specificity for glutathione S-transferase P1-1.
    Chemical research in toxicology, 2002, Volume: 15, Issue:7

    Topics: Animals; Breast Neoplasms; Enzyme Inhibitors; Equilenin; Estrogens, Catechol; Glutathione S-Transferase pi; Glutathione Transferase; Horses; Humans; Isoenzymes; Kinetics; Substrate Specificity; Tumor Cells, Cultured

2002
Equine catechol estrogen 4-hydroxyequilenin is a more potent inhibitor of the variant form of catechol-O-methyltransferase.
    Chemical research in toxicology, 2004, Volume: 17, Issue:4

    Topics: Breast Neoplasms; Catechol O-Methyltransferase; Catechol O-Methyltransferase Inhibitors; Equilenin; Estradiol Congeners; Female; Humans; Methylation; Risk Factors; Temperature

2004
Characterization of two new variants of human catechol O-methyltransferase in vitro.
    Cancer letters, 2005, Dec-08, Volume: 230, Issue:1

    Topics: Alanine; Breast Neoplasms; Catechol O-Methyltransferase; DNA Methylation; Equilenin; Escherichia coli; Estrogen Replacement Therapy; Female; Humans; Mutagenesis, Site-Directed; Plasmids; Polymorphism, Genetic; Serine; Temperature

2005
A metabolite of equine estrogens, 4-hydroxyequilenin, induces DNA damage and apoptosis in breast cancer cell lines.
    Chemical research in toxicology, 2000, Volume: 13, Issue:5

    Topics: Apoptosis; Breast Neoplasms; Cell Survival; Comet Assay; DNA Damage; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelial Cells; Equilenin; Estradiol Congeners; Estrogens, Catechol; Female; Humans; Hydroxyestrones; Tumor Cells, Cultured

2000
Oxidative DNA damage induced by equine estrogen metabolites: role of estrogen receptor alpha.
    Chemical research in toxicology, 2002, Volume: 15, Issue:4

    Topics: Binding, Competitive; Breast Neoplasms; Cell Survival; Comet Assay; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Equilenin; Estradiol Congeners; Estrogen Receptor alpha; Female; Humans; Reactive Oxygen Species; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Tamoxifen; Tumor Cells, Cultured

2002