Compounds > 4-ethoxy-3-phenylsulfonylfuroxan

4-ethoxy-3-phenylsulfonylfuroxan and Arteriosclerosis

4-ethoxy-3-phenylsulfonylfuroxan has been researched along with Arteriosclerosis* in 1 studies

Other Studies

1 other study(ies) available for 4-ethoxy-3-phenylsulfonylfuroxan and Arteriosclerosis

ArticleYear
Development of a new class of potential antiatherosclerosis agents: NO-donor antioxidants.
    Bioorganic & medicinal chemistry letters, 2004, Dec-20, Volume: 14, Issue:24

    A new class of NO-donor phenol derivatives is described. The products were obtained by joining appropriate phenols with either nitrooxy or 3-phenylsulfonylfuroxan-4-yloxy moieties. All the compounds proved to inhibit the ferrous salt/ascorbate induced lipidic peroxidation of membrane lipids of rat hepatocytes. They were also capable of dilating rat aorta strips precontracted with phenylephrine.

    Topics: Animals; Antioxidants; Aorta; Arteriosclerosis; Ascorbic Acid; Ferrous Compounds; Hepatocytes; Hypolipidemic Agents; Lipid Peroxidation; Male; Membrane Lipids; Nitric Oxide Donors; Phenols; Phenylephrine; Rats; Rats, Wistar; Structure-Activity Relationship; Thiobarbituric Acid Reactive Substances

2004