4-diphenylacetoxy-1,1-dimethylpiperidinium has been researched along with Xerostomia in 2 studies
4-diphenylacetoxy-1,1-dimethylpiperidinium: muscarinic receptor antagonist; RN given refers to parent cpd; do not confuse abbreviation 4-DAMP with a similar cpd which does not contain dimethyl groups
4-DAMP(1+) : A quaternary ammonium salt obtained by formal methylation of the tertiary amino function of 4-diphenylacetoxy-N-methylpiperidine.
Xerostomia: Decreased salivary flow.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Using rats, we examined the muscarinic receptor subtype mediating pilocarpine-induced parotid salivary secretion and the contributions of ion transporter systems (effluxes of K+ and Cl(-)) and aquaporin-5 (AQP5) translocation to this response in parotid glands in irradiated-induced xerostomia." | 3.75 | Salivation triggered by pilocarpine involves aquaporin-5 in normal rats but not in irradiated rats. ( Asari, T; Kusama, H; Maruyama, K, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Asari, T | 1 |
| Maruyama, K | 1 |
| Kusama, H | 1 |
| Passafaro, D | 1 |
| Reina, S | 1 |
| Sterin-Borda, L | 1 |
| Borda, E | 1 |
2 other studies available for 4-diphenylacetoxy-1,1-dimethylpiperidinium and Xerostomia
| Article | Year |
|---|---|
Salivation triggered by pilocarpine involves aquaporin-5 in normal rats but not in irradiated rats.
Topics: Animals; Aquaporin 5; Calcium; Male; Muscarinic Agonists; Muscarinic Antagonists; Parotid Gland; Pil | 2009 |
Cholinergic autoantibodies from primary Sjögren's syndrome modulate submandibular gland Na+/K+-ATPase activity via prostaglandin E2 and cyclic AMP.
Topics: Adult; Animals; Autoantibodies; Cells, Cultured; Cyclic AMP; Dinoprostone; Female; Humans; Immunoglo | 2010 |